Entrance Exam Hema WITH ANSWERS
Entrance Exam Hema WITH ANSWERS
Entrance Exam Hema WITH ANSWERS
NAME________________________________________
MULTIPLE CHOICE QUESTIONS. CHOOSE THE BEST ANSWER.
___1. Oral chemotherapeutic drug that induces differentiation of leukemic
cells bearing t(15;17)
A. Cytarabine
C. Tretinoin
B. Methotrexate
D. Daunorubicin
___2. Morphologic FAB classification associated with disseminated
intravascular couagulation
A. M4
C. M2
B. M3
D. M5
___3. All four globin loci are deleted in what form of thalassemia
A. Homozygous thalassemia trait
B. Hemoglobin H disease
C. Heterozygous thalassemia trait
D. Hydrops fetalis
___4. Stage of Iron deficiency in which the demands for iron exceeds the
bodys ability to absorb iron from the diet
A. iron deficient erythropoiesis
C. iron deficiency
anemia
B. negative iron balance
D. Normal
___5. Serum ferritin level diagnostic of absent body iron stores
A. <100ug/L
C. <15ug/L
B. <30ug/L
D. <40ug/L
___6. Diagnostic test for Autoimmune Hemolytic Anemia
A.
B.
C.
D.
Antiglobulin test
Hemoglobin electrophoresis
Immunophenotyping
Osmotic fragility test
C.
D. Cortisol
Hemoglobin level
Presence of skeletal lytic lesions
Creatinine level
2 microglobulin level
3
CASES. CHOOSE THE BEST ANSWER.
A.J. 24 year old male is a diagnosed case of mild haemophilia A who
presented in the emergency room in pain and was noted to have
hemarthroses on the Left Knee.
_____1. Initial management of AJ
A.
B.
C.
D.
R.T. 27 year old female presented with multiple hematoma on the lower
extremities and fatigue in the emergency room. CBC done showed: Hgb
72g/l Hct 24 WBC 57,800 neutrophils =12 Lymphocyte=32 monocyte=1
blasts=55 platelet count=20,000/cumm
____2. Initial Impression
A. Chronic Leukemia
B. Acute Leukemia
C. Myelodysplastic syndrome
D. Idiopathic Myelofibrosis
Bone marrow aspiration was done as well as cytogentic studies which
revealed t(6;9), inv(3), and inv (16)
____3. Prognosis of patient RT
A. Good prognosis after treatment with cytarabine
B. Favorable response to Daunorubicin
C. Unfavorable due to the presence inv 16
D. Poor prognosis due to complex karyotye
E.H. 75 year old was diagnosed with Chronic Myelogenous Leukemia after
detection of BCR-ABL by FISH
____4. Treatment of Choice for E.H.
A. Imatinib besylate
B. Allogeneic marrow transplantation
C. Sunitinib
D. Busulfan
____5. Cytogenetic hallmark in patients with CML
A. t(8;21)
B. t(9;22)
C. t(15;17)
D. inv 3
4
After 6 months of treatment his CBC showed Hgb 87 Hct 29 WBC 15,000
neu 26 lym 10 mono 5 baso 22 eos 10 blast 2 myelocyte 11 promyelocyte
24 platelet count 95,000/cumm
____6. Patient is in what phase of CML?
A. normal phase
B. blastic phase
C. chronic phase
D. accelerated phase
Digital ischemia
Erythromelalgia
Gout
Thrombosis
AV, 49 year old female presents with Left Upper Quadrant discomfort.
Physical examination showed the spleen to be enlarged measuring 20cm
below the left subcostal margin. CBC: Hgb 110 G/L Hct 0.36 WBC: 32x109/L
promyelocytes 15% metamyelocytes 20% myelocytes 10% bands 8%
segmenters 37% lymphocyte 10% platelets 650000. Peripheral smear
showed presence of tear-drop shaped cells and nucleated red blood cells.
6
D. Progressive Disease
TRUE or FALSE.
1.
2.
4.
5.
6.
7.
7
__T__C. Prolonged Activated Partial Thromboplastin Time
8.
9.