Cytospin Brochure Compl

Shandon
Cytospin 4
Cytocentrifuge
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Thin-layer
Cell Preparation
System
a leader in anatomical pathology
Shandon Cytospin 4
Cytocentrifuge
The Cytospin was the first device to

use carefully controlled centrifugation
to separate and deposit a thin layer
of cells on slides while maintaining
cellular integrity. It produces better
cell capture and good representation of
all cell types present in homogeneous
liquid samples.
Shandon Cytospin 4 Cytocentrifuge

The ultimate thin-layer cell preparation system
Features
Accepts all protocols from Cytospin 1,
2, and 3.
Redesigned Lid-release Mechanism
allows for one-handed opening and
closing of the outer lid for easy access.
As an added safety measure, the
Cytospin will only operate when the lid
is locked into position. The lid remains
locked at all times during rotation.
The polycarbonate window allows the
operator to see the Sealed Head during
cytocentrifugation.
Excellent safety design prevents
accidental fluid spillage from
damaging the mechanical or electronic
components and allows for easy
disinfecting. It meets stringent IEC
61010 standards for centrifuge safety.
The Cytospin has been synonymous with
cytocentrifugation for over 35 years.
More than 15,000 laboratories worldwide
use this simple, reliable instrument.
It provides economical thin-layer
preparations from any liquid matrix,
especially hypocellular fluids such as
spinal fluid.
Pull-out Program Card allows for up

to nine programs to be logged for fast
and convenient retrieval (erasable ink
pen included).
Safe and Reliable

The Cytospin is designed to protect the
operator before, during and after sample
preparation. Safety is our top priority. The
ability to load the Cytospin Sealed Head in
a microbiological cabinet is the ultimate
safety procedure.
Auto-locking, plastic outer lid
Autoclavable Sealed Head
Disposable sample chambers with caps
Safety alarms that protect users and
specimens
Wipe-clean control panel
Simple and Precise Controls

Protected Program Memory stores
Control feature has a standby power
up to 23 routines for instant recall and
saving mode. Displays are also turned
protects from power loss.
on and off by the standby key.
Program Key Pad has easy-touch
Safety Alarms include an audible
design that allows for easier keystrokes
alarm that signals the operator if the
and more intuitive programming.
Cytospin is out of balance, outside the
Speed window displays the
speed tolerance, or if the lid is not
programmed spinning speeds from
properly locked. As an extra measure of
200 2000 rpm.
safety for the user, the unit will not spin
Three Acceleration Control buttons

allow the operator excellent flexibility
if the lid is not locked.

Specimen safety alarm feature
and exceptional protection for fragile
has been added to remind users at
samples.
one-minute intervals to remove
Time window displays the programmed

and remaining run time from 1 99
minutes.
specimens, protect them from

air-drying and ensure consistent
results.
Simple Principle for Excellent Presentation

In-Load Position (Stopped)

In Operation (Spin)
Using centrifugal principles, the Cytospin deposits cells

onto a clearly-defined area of a glass slide and allows
for the absorption of the residual fluid into the sample
chambers filter card. Cytocentrifugation also constructively
flattens cells for excellent nuclear presentation. During
operation, the instruments spinning action tilts Cytofunnels
upright and centrifuges cells onto the deposition area of the
slide, giving all cell types equal opportunity for presentation.
In the Load or Stop position, this unique tilting feature
reduces cell loss by preventing residual fluid from coming
into contact with the prepared slide.
Shandon Cytospin 4
Cytocentrifuge
Disciplines That Use the Cytospin
Cytology
Hematology/Oncology
Still the gold standard for NonGynecological Cytology, especially

hypocellular fluids.
Easy to achieve a constant cell/unit

volume.
Many types of collection fluids and

funnel options to choose from.
Quality presentation at a fraction
of the cost of other thin-layer
technologies.
Prepares both air dried and fixed
specimens.
Microbiology
Micro-organisms are often present in
low numbers from limited sample
volumes. Cytocentrifugation effectively
spins the micro-organisms onto the slide,
maximizing the yield and presenting
those organisms in a clean, defined
area, allowing for straightforward
morphological identification.
Only a small sample volume is needed
so multiple samples may be run for a
variety of special staining and support
testing. It also concentrates samples
for Gram stains.
Excellent for all fluids, bone marrow,

and peripheral blood.
Even with a cell count of zero, the
Cytospin often locates the few cells in
the fluid that the counter missed.
Virology
There are many published technical
papers utilizing the Cytospin for the
rapid detection of respiratory viruses,
CMV Detection, ISH, FISH, etc.
Research/General Use
The most cost-effective, time-effective
way to make quality thin-layer cell
presentations.
Excellent for molecular studies,
specialized staining applications,
and EM.
Used in veterinary, dental and
chemosensitivity protocols.
Reagents and
Supplies
Collection Fluids
Shandon Cytoslides
CytoRich Red Collection Fluid*

Concentrated Formula
Specially marked Slides for the Cytospin

Specimen area is outlined for rapid location during screening.
All slides are 75 x 25 mm, made from high-quality optical glass.
Ready-to-use alcohol-based fluid.

Lyses RBCs and solubilizes protein.
Helps optimize diagnostic cell yield by
removing blood before presentation.
Helps soften mucus for greater
cell retrieval.
Compatible with immunohistochemistry.
Pre-filled containers available.
Coated Slides
Eliminates the need for albumin coating procedures. Saves labor
and resource time.
Eliminates background staining on albuminized, IHC or ISH
processed slides.
Single Cytoslides
Specially made for use with Cytospin
Single Sample Chambers.
A white, 12 mm diameter circle on
the slide defines the area where cells
will be displayed to allow for efficient
and rapid location.
Uncoated slides available with circle
on front or back.
Shandon Cytospin Collection Fluid

Ready-to-use alcohol/CARBOWAX
(PEG) combination for direct
specimen collection and fixation.
Permits storage of specimens
or unstained slides for weeks.
Pre-filled containers available.
Shandon Mucolexx
Double Cytoslides
Specially produced for use with Double
Cytofunnel Chambers.
Each specimen is displayed onto the
slide within a circle marked 1 or 2
which corresponds with the Double
Cytofunnel chamber.
Multi-purpose specimen transport

medium.
Liquefies (with agitation) mucoid
specimens.
Short-term preservation of specimens.
Shandon Cell-Fixx
Spray fixative for convenient preparation of slides.
Includes CARBOWAX which coats the smear to
maintain cellular detail.
Prevents air drying artifact and cell loss.
Description
CytoRich Red Collection Fluid
Pkg/Qty
4L bottle
Mask Cytoslides
Specially produced for
immunofluorescence.
Black-coating masks out UV light
so that only the specimen within
the circle can be viewed through a
microscope.
Order Number
B9990800
500 ml bottle (2 per pack)
B9990801
Case of 180 20ml vials (filled to 10ml)
B9990802
Case of 125 120ml cup (filled to 60ml)
B9990803
Cytospin Collection Fluid
10L bottle x 2
9990310
Mucolexx Transport Fluid
4L bottle (with pump)

500ml bottles x 2
125/Case 120ml cups (filled to 60ml)
4L bottle
500ml bottles x 3
50/Case 120ml cups (filled to 60ml)
50ml pump spray bottle x 6
6768001
6768315
9990323
9990371
9990370
9990375
6768326
Cell-Fixx Spray Fixative
Description
Cytoslide, Single Circle
coated circle on back
Pkg/Qty
100/box
Order Number
5991056

non-coated circle on back
100/box
5991051

non-coated circle on front
100/box
5991059
Cytoslide, Double Circle, coated

Cytoslide, Double Circle, non-coated
Cytoslide, Single Circle, Black mask
Cytoslide, Double Circle, Blue mask
100/box
100/box
100/box
100/box
5991055
5991054
5991057
B5991050
* CytoRich Red is manufactured under the license of TriPath Imaging

CARBOWAX is a registered trademark of Union Carbide Chemicals
Shandon EZ
Cytofunnels
NEW
Shandon EZ Cytofunnel Sample Chambers

Shandon EZ Cytofunnel
Intended for single use on the Shandon Cytospin Cytocentrifuge.

Optimizes cell yield.
Safe reduces the risk of exposure to pathogenic samples.
Disposable eliminates time-consuming decontamination and cleaning.
Decreases the possibility of cross-contamination.
Eliminates the need for metal Shandon Cytoclips.
Closure caps provided with kit.
Simple and easy to use.
Produces more cost-effective thin-layer preparations when
compared to other thin-layer methods.
No more clips!
Easy-to-use operation
illustrations included
in package
Shandon EZ Megafunnel
Designed for convenient preparation of larger volume samples.
Shandon Cytofunnels designed for spinning large samples up
to 6 ml.
Minimizes the need to pre-centrifuge.
Cell deposition area of 22 x 14.75 mm (325 mm2) for increased
cell yield.
Shandon Megafunnel Cytoslides included.
Can prepare both air-dried and fixed preparations, providing
additional valuable diagnostic information
Description
Pkg/Qty
Shandon EZ Megafunnel
25/box
Order Number
A78710001
Shandon EZ
Cytofunnels
NEW
Shandon EZ Single Cytofunnel
with White Filter Cards
Disposable Sample Chambers with White Filter Cards

Use for sample volumes up to 0.5 ml.
Cell deposition area of 6 mm in diameter (28mm2)
Pre-attached white filter card for high absorbency.
Description
Pkg/Qty

with White Filter Cards and Caps
50/box
Order Number
A78710003

with Brown Filter Cards
Disposable Sample Chambers with Brown Filter Cards.

Use for sample volumes of 0.4 ml or less.
Cell deposition area of 6 mm in diameter (28mm2)
Pre-attached brown filter card for slower absorbency.
Excellent for scanty specimens such as CSF.
Description
Pkg/Qty

with Brown Filter Cards and Caps
50/box
Order Number
A78710004
Shandon EZ Double Cytofunnels
Disposable Sample Chambers

Allows 2 sample deposition areas on a single slide.
Double the number of sample presentations per run.
Funnel markings correspond to slide markings for simple
identification.
Pre-attached filter card.
Ideal for use with immunochemistry techniques.
Description
Pkg/Qty
Shandon EZ Double Cytofunnels

with White Filter Cards and Caps
50/box
Order Number
A78710005
Shandon Cytospin Sealed Head

One Sealed Head is included with the Cytospin, but many
laboratories shorten preparation time by having a second
Sealed Head ready for when the first finishes processing.
Autoclavable, 12-chamber Head seals completely.
Description
Pkg/Qty
Cytospin Sealed Head
Each
Order Number
59910018
Shandon
Cytology Stains
Shandon Cytospin 4 Cytocentrifuge

Description
Shandon Cytospin 4
Order Number
with Starter Kit
without Starter Kit
A78300001
A78300002
Physical Specifications
Dimensions (H x W x D)
With Closed Lid:
9.5" x 16" x 24.5" (24 x 40.5 x 62 cm)
With Opened Lid:
25" x 16" x 24.5" (62.5 x 40.5 x 62 cm)
Weight
26.5 lbs. (12 kg)
Power Requirements
150VA (maximum)
Included with Product*
Sealed Head/Rotor
Marking Pen
Operator Manual (specify language)
Service Record Book
Standard Workflow Diagram
Each
Each
Each
Order Number
59910018
AP14891
A78310250
A78310252
A783-1001
* Contents, Packaging, and Quantities of items listed under Included with Product are subject to change
without prior notice.
Additional Accessories
Service Manual
Sealed Head Seals
Starter Kit
Assortment of Disposable Cytofunnels
Glass Microscope Slides
Each
3 / Pk.
Shandon EA-50
Agency Approvals
Polychromatic cytoplasmic stain.
IEC 61010, CSA, UL, and CE Mark (IVDD compliant).
Order Number
A78310251
59910019
Clearly differentiates cellular components with pink, green,

and blue-green hues.
Shandon EA-65
Polychromatic cytoplasmic stain.
Lower concentration of Light Green improves
expression of eosin-stained components.
Ideal for thicker non-GYN preparations.
Shandon OG-6
Demonstrates keratin in cytoplasm.
Description
Shandon EA-50
Shandon EA-50
Shandon EA-65
Shandon EA-65
Shandon OG-6
Shandon OG-6
Pkg/Qty
4Lx1
1Lx2
4Lx1
1Lx2
4Lx1
1Lx2
Shandon Kwik-Diff Stains

Order Number
6766002
6766001
6766004
6766003
6766006
6766005
Shandon Cytology Spatula
A quick alternative to traditional Wrights and Giemsa Staining

procedures.
Kit components include: Reagent 1, Fixative; Reagent 2, Eosin;
and Reagent 3, Methylene Blue.
Available in kit for or as individual components.
Economical.
Designed with classic Ayre end and
tapered tip.
Made from smooth, select wood for
excellent cell retention and release.
Description
Shandon Cytology Spatula
Fast 3-step differential stain for bone marrows, smears, FNAs

and microorganisms such as Helicobacter plyori.
Pkg/Qty
1000 (40 bags x 25)
Order Numberr
9990330
Description
Shandon Kwik-Diff Stain Kit
Shandon Kwik-Diff Stain Kit
Shandon Kwik-Diff Reagent 1
Fixative
Eosin
Methylene Blue
Pkg/Qty
500 ml Reagent Size
125 ml Reagent Size
4L
Order Number
9990700
9990701
9990705
4L
9990706
4L
9990707
Leading the world in high-tech instruments, Thermo Electron Corporation helps life science, laboratory and industrial customers advance scientific knowledge, enable drug
discovery, improve manufacturing processes, and protect people and the environment with instruments, scientific equipment, and sample-in/knowledge-out solutions.
Based in Waltham, Massachusetts, Thermo Electron Corporation has revenues of more than $2 billion, and employs approximately 11,000 people in 30 countries worldwide.
Anatomical Pathology USA

Anatomical Pathology International
Anatomical Pathology Latin America/Canada
Tel: 1-800-547-7429 1-412-788-1133
Tel: 0800 0189396 +44 (0) 1928 562600
Tel: 1-412-788-2460
Fax: 1-412-788-1138
Fax: +44 (0) 1928 562627
Fax: 1-412-788-2480
Email: clinical.diagnostics@thermo.com
Internet: www.thermo.com/shandon
M312118 Rev 1 06/04 10M
ISO 9001 Registered Company

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What are the main features of the Cytospin 4 cytocentrifuge?

What are the main features of the Cytospin 4 cytocentrifuge?

How does the Cytospin work to prepare thin-layer cell samples?

How does the Cytospin work to prepare thin-layer cell samples?

Shandon

a leader in anatomical pathology

The Cytospin was the first device to

Shandon Cytospin 4 Cytocentrifuge

Pull-out Program Card allows for up

Safe and Reliable

Simple and Precise Controls

Control feature has a standby power

up to 23 routines for instant recall and

saving mode. Displays are also turned

protects from power loss.

on and off by the standby key.

Program Key Pad has easy-touch

Safety Alarms include an audible

design that allows for easier keystrokes

alarm that signals the operator if the

and more intuitive programming.

Cytospin is out of balance, outside the

Speed window displays the

speed tolerance, or if the lid is not

programmed spinning speeds from

properly locked. As an extra measure of

200 2000 rpm.

safety for the user, the unit will not spin

Three Acceleration Control buttons

if the lid is not locked.

and exceptional protection for fragile

has been added to remind users at

one-minute intervals to remove

Time window displays the programmed

specimens, protect them from

Simple Principle for Excellent Presentation

In-Load Position (Stopped)

Using centrifugal principles, the Cytospin deposits cells

Still the gold standard for NonGynecological Cytology, especially

Easy to achieve a constant cell/unit

Many types of collection fluids and

Excellent for all fluids, bone marrow,

CytoRich Red Collection Fluid*

Specially marked Slides for the Cytospin

Ready-to-use alcohol-based fluid.

Shandon Cytospin Collection Fluid

Multi-purpose specimen transport

500 ml bottle (2 per pack)

Case of 180 20ml vials (filled to 10ml)

Case of 125 120ml cup (filled to 60ml)

Cytospin Collection Fluid

Mucolexx Transport Fluid

4L bottle (with pump)

Cell-Fixx Spray Fixative

Cytoslide, Single Circle

Cytoslide, Single Circle

Cytoslide, Double Circle, coated

* CytoRich Red is manufactured under the license of TriPath Imaging

Shandon EZ Cytofunnel Sample Chambers

Intended for single use on the Shandon Cytospin Cytocentrifuge.