Nothing Special   »   [go: up one dir, main page]
Scribd Logo
Upload

Welcome to Scribd!

  • 3 views

    Khan Academy - Foundation 1 - Biomolecules 4

    Uploaded by

    Jyothi

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    Khan Academy - Foundation 1 - Biomolecules 4

    Uploaded by

    Jyothi
    3 views1 page

    Original Title

    Khan Academy - Foundation 1_ Biomolecules 4

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    3 views1 page

    Khan Academy - Foundation 1 - Biomolecules 4

    Uploaded by

    Jyothi

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 1

    peptide bonds : formation and cleavage

    H
    1. electrons from amino group bond w/ carbon from carbonyl group
    2
    . HeO released dipeptide formed,

    :
    "I
    OH - H O released
    HNVXN -
    -

    Ri
    & peptide bond : amide bond formed btwn 2 amino acids (rigia planar bona
    ,

    N terminal = N -
    C -
    C -
    N -
    c -
    C -
    N -
    C -
    C >
    - C + erminal

    R R ↳
    ~
    residue

    breaking of peptide bonds


    can be broken through hydrolysis
    or
    Il I

    HaNY
    !
    hydrolysis can happen w/ help of strong acids or proteolytic enzymes
    > heat-strong acids breaks apart polypeptide (non-specific)
    ~ acia hydrolysis -

    Proteolysis -
    ~ > protease breaks
    apart certain peptide bonds (specific)

    classification of amino acids

    ~
    charge of side chain
    ~ ability of side chain to H-bond
    ~ acidity or basicity of the side chain

    non-polar ,
    hydrophonic polar hydrophilic
    ,

    / & 12
    alkyl aromatic neutral acidic basic

    Alky1 : H Cha CHICHa) CHICHaCha CHICH(CHs) HCCHs)CHeCHa TIX OH


    ↑ ,
    !
    dianine
    I
    H
    glycine valine methionine leucine isoleucine proline
    "

    --
    aromatic :
    che- - 1+
    I
    ↑
    &
    ↑
    phenylalanine tryptophan

    You might also like