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Condyloma Lata

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ACTAS Dermo-Sifiliográficas 114 (2023) 447

IMAGING IN DERMATOLOGY

Condylomata Lata and Papular Rash of Secondary


Syphilis
Condiloma lata y erupción papular de sífilis secundaria
A. Herzum ∗ , M. Burlando, C. Micalizzi, A. Parodi

DISSAL, Section of Dermatology, University of Genoa, Ospedale Policlinico San Martino IRCCS, Genova, Italy

A 41-year-old-man presented with a 2-month history of


painful perianal lesions and various maculo-papular lesions
that occurred simultaneously on his lower limbs.
He reported generalized fatigue and previous unpro-
tected homosexual intercourse.
Physical examination evidenced moist-to-macerated,
flat-topped, tumor-like nodules around the anus, sur-
rounded by erythemato-squamous annular patches and
scattered papules (Fig. 1A).
On the legs and soles, coppery-shaded erythemato-
squamous, nummular plaques and papules were noted, some
of which with a collarette of scale (Fig. 1B).
The clinical presentation of these lesion was highly sug-
gestive for condylomata lata (CL) and for secondary syphilis Figure 1
papular squamous rash.
Positive TPHA and VDRL confirmed the clinical suspect of
Dermatologists play a key role in identifying and treating
secondary syphilis. The patient was treated with long-acting
syphilis. It is therefore of great importance to increase the
Benzathine G-penicillin (2.4 MU intramuscularly).
clinicians’ ability to diagnose syphilis precociously, to pre-
Secondary syphilis is polymorphic, causing initial maculo-
vent complications, destructive consequences and disease
papular rush, followed by persistent erythemato-papulo-
transmission.2
squamous lesions, as on our patient’s legs, soles and
perineum.1 Also, 6---23% present CL: vegetating, flat-topped,
infectious lesions, painful when macerated by friction,
which also perpetuates dissemination.

∗ Corresponding author.
E-mail address: astridherzum@yahoo.it (A. Herzum).

https://doi.org/10.1016/j.ad.2022.01.046
0001-7310/© 2022 AEDV. Published by Elsevier España, S.L.U. This is an open access article under the CC BY-NC-ND license (http://
creativecommons.org/licenses/by-nc-nd/4.0/).

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