Title: Crafting a Comprehensive Literature Review on Diabetes Mellitus in Nigeria

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Various factors help in explaining why there exists such significance. The diseases are such as
diabetes, cancer, respiratory disease and heart disease. In Kingdom Saudi Arabia, hypertension,
diabetes along with coronary artery diseases has become an extreme challenge to the countries health
care system. Download Free PDF View PDF A Review on Diabetes Mellitus-An Annihilatory
Metabolic Disorder Reddi Nagesh Download Free PDF View PDF International journal of health
sciences Health and treatment of diabetes mellitus Dr. I Wayan Suryasa Some reflections will be
presented on diabetes mellitus, which is a very common chronic disease in daily life due to different
causes where diet and sedentary lifestyle directly influence. In type 1 diabetes, symptoms tend to
come on quickly and be more severe. What is known is that your immune system which normally
fights harmful bacteria or viruses attacks and destroys your insulin-producing cells in the pancreas.
Diabetes complication Diabetes and depression are spread worldly. Type 2 Diabetes Middle-aged
individuals and older people are highly vulnerable to this type of diabetes. Keep on browsing if you
are OK with that, or find out how to manage cookies. In addition to that, some eating habits are
native in Kingdom of Saudi Arabia. Excess sugar can injure the walls of the tiny blood vessels
(capillaries) that nourish your nerves, especially in your legs. Diet and lifestyle strategies are to
reduce weight, improve glycaemic control and reduce the risk of cardiovascular complications in
diabetes. Type 2 diabetes may increase the risk of dementia, such as Alzheimer’s disease. Hence, the
need to explore oral antidiabetic drugs of natural origin with minimal side effects is highly essential.
Depression and poor glycemic control: a meta-analyticreview of the literature. Download Free PDF
View PDF See Full PDF Download PDF Loading Preview Sorry, preview is currently unavailable.
Type two diabetes, on the other hand, is associated with poor lifestyle choices such physical
inactivity and unhealthy diet. Other forms of diabetes mellitus such as idiopathic type one diabetes
mellitus, fulminant type 1 diabetes, latent autoimmune diabetes in adults and maturity onset diabetes
of the young. Approximately eighty percent (80%) of the deaths occur in middle and low-income
countries. The reason being that, the insulin produced by the pancreas is not adequate enough or it is
ineffective thus making the body unable to utilize the food carbohydrates. The deaths are projected
to rise by 13 %( 59%) by 2030. Other individuals who have some residual hypoglycemic agent
secretion but require exogenous insulin for adequate glycemic control can survive without it. Insulin
deficiency in turn leads to chronic hyperglycemia with disturbances of carbohydrate, fat and protein
metabolism. The effect of uncontrolled diabetes is hyperglycemia or high blood glucose).
Conclusion: Herbal products have been thought to be inherently safe, because of their natural origin
and traditional use rather than based on systemic studies. East Mediterr Health J 2004, 10: p. 663-
670. 4. Anderson RJ, Freedland EF, Clouse RE, Lustman PJ. It is found that there is a wide, yet
uneven support for active components of major medicinal. Apart from provision of these services,
there is need to equip health care professionals with adequate knowledge to improve their
significance in care planning. Diabetes is best controlled either by diet alone and exercise (non-
pharmacological) or diet with herbal or oral hypoglycemic agents or insulin (pharmacological).This
review explores about diabetes mellitus and its management. Too much sugar in your blood can lead
to serious health problems.
These individuals therefore do not require insulin. Thus, there is need to address diabetes as a public
health issue. Diabetes mellitus is a metabolic disorder characterized by hyperglycaemia in which
glucose is underutilized due to defects in insulin secretion, insulin action, or both. Sometimes family
members of people with type 1 diabetes are tested for the presence of diabetes auto antibodies.
Various factors help in explaining why there exists such significance. Potentially reversible diabetes
conditions include prediabetes — when your blood sugar levels are higher than normal, but not high
enough to be classified as diabetes and gestational diabetes, which occurs during pregnancy but may
resolve after the baby is delivered. According to the literature review, diabetes mellitus is a persistent
condition with various risk factors and serious complications that affect the quality of life.
Depression and poor glycemic control: a meta-analyticreview of the literature. Diabetes aggressive
treatment and intensive treatment strategies aids in reducing its complication through earlier
management and detection. This study reviewed existing information on medicinal plants used for
the treatment of diabetes mellitus from various sources. The epidemiology of major depressive
disorder: results from the National Comorbidity Survey Replication (NCS-R). Many of the synthetic
medicine such as sulfonylureas, biguanides, alpha-glucosidase inhibitor and thiazolidinediones are
the diabetic agents currently available to control the hyperglycemic condition. Google search engine
was used for accessing published articles from databases like Google Scholar, Research Gate,
PubMed, NCBI, NDSS, PMID, PMCID, Cochrane Database and Clindamed international library.
The cause of insulin-dependent Diabetes mellitus is unknown, but some research shows a viral
infection may play a positive role where it causes the destruction of the insulin-secreting tissues that
often lead to inflammation of the pancreas. The major symptom of diabetes mellitus includes
excessive thirst, frequent urination, increased appetite, weakness, fatigue and weight loss. High
blood glucose levels are manifested during diabetes mellitus because of inadequate pancreatic insulin
secretion or poor insulin-directed mobilization of cellular glucose. Insulin deficiency in turn leads to
chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism. Today, this
has prompted the search for cheap, safe, and reliable drugs from medicinal plants. Conclusion:
Herbal products have been thought to be inherently safe, because of their natural origin and
traditional use rather than based on systemic studies. Physical activity helps you control your
weight, uses up glucose as energy and makes your cells more sensitive to insulin. Such drugs acts by
either increasing the secretion of insulin from pancreas or reducing plasma glucose concentrations by
increasing glucose uptake and decreasing gluconeogenesis. It is also necessary to subsidies the cost of
oral hypoglycaemic drugs and insulin injections used by diabetics especially in developing countries
so that diabetics can easily afford them. They achieve a healthy body and mind at the present time
that humanity is engaged in eradicating the viruses that have affected the world population, which
would. However, environmental factors such as viral infections that are unavoidable but common
contribute to this type of diabetes. Circumstances such as exposure to a viral illness likely play some
role in type 1 diabetes. If you gave birth to a baby weighing more than 9 pounds (4 kilograms),
you’re also at risk of type 2 diabetes. Two major types of DM exist; the first type is characterized by
insufficient production of insulin and in the other type the target cells do not respond to insulin.
Approximately eighty percent (80%) of the deaths occur in middle and low-income countries. The
prevalence of diabetes patients is rising at epidemic proportions throughout the world. In simple
terms, diabetes is generally due to the absence or lack of effective functioning of insulin.
The diseases are such as diabetes, cancer, respiratory disease and heart disease. Studies reveal the role
of crude extracts of plants with potential antidiabetic activity in alloxan and streptozotocin-induced
diabetic animals. Weight is not believed to be a factor in type 1 diabetes. Treatment of Type 1
diabetes Individuals with Type 1 diabetes require insulin injections. It can lead to many
complications if not treated properly. Download Free PDF View PDF Pharmacologyonline
DIABETES MELLITUS. Adobe InDesign Design pixel-perfect content like flyers, magazines and
more with Adobe InDesign. If you have low levels of high-density lipoprotein (HDL), or “good,”
cholesterol, your risk of type 2 diabetes is higher. Type 2 DM or non-insulin-dependent diabetes
mellitus (NIDDM), results from insulin resistance, a condition where cells fail to use insulin properly,
with or without an absolute insulin deficiency. Being overweight is strongly linked to the
development of type 2 diabetes, but not everyone with type 2 is overweight. These individuals
therefore do not require insulin. But not everyone who has these auto antibodies develops diabetes.
To achieve successful self-management, it is advisable to offer patients with information about their
conditions. Potentially reversible diabetes conditions include prediabetes — when your blood sugar
levels are higher than normal, but not high enough to be classified as diabetes and gestational
diabetes, which occurs during pregnancy but may resolve after the baby is delivered. Too much
sugar in your blood can lead to serious health problems. Teams Enable groups of users to work
together to streamline your digital publishing. Diabetes as public health problem Incidents and
prevalence of diabetes are quite alarming. Every year, a major portion of the annual health budget is
spent on diabetes and related illnesses. The prevalence of diabetes patients is rising at epidemic
proportions throughout the world. An illness method could also be gift however might not have
progressed far enough to cause hyperglycemia. Left untreated, cuts and blisters can develop serious
infections, which often heal poorly. You can download the paper by clicking the button above. It is
therefore of great clinical significance if research is conducted on specific population of diabetes
patients. Glucose is vital to your health because it’s an important source of energy for the cells that
make up your muscles and tissues. Type II diabetes in young has increased 30 fold over the last 20
years concomitant with an increase in obesity. You’re also more likely to develop diabetes typically
type 2 diabetes as you get older. Saudi Med Journal 2011, 32:953-1050. 22. Stuckler, D. Population
Causes and Consequences of Leading Chronic Diseases: A comparative Analysis of Prevailing
Explanations. Diabetes has a direct impact on the development of particular retinopathy,
nephropathy, neuropathy, heart vascular, and cerebrovascular illnesses. Insulin is the principal
hormone that regulates uptake of glucose into most cells from the blood and deficiency of insulin or
insensitivity of its receptor cells plays a central role in all forms of diabetes mellitus. As of 2014, an
estimated 387 million people had diabetes mellitus worldwide.