MACANLALAY, Ralph Elvin

BSN 3F-D

DRUG NAME MECHANISM OF ACTION ADVERSE EFFECTS NURSING RESPOSIBILITY

Generic Name: Inhibits bacterial protein CV: Thrombophlebitis Dx:
Clindamycin synthesis by binding to the GI: Nausea; pseudomembranous > Monitor Renal, Hepatic, and
50S subunit of the ribosome colitis; abdominal pain; hematopoietic function during
Dose: INDICATIONS & diarrhea; vomiting prolonged therapy
300mg CONTRAINDICATIONS Hematologic: > Observe for signs for
Indication: Thrombocytopenia; transient superinfection
Route: Infection caused by sensitive leukemia; eosinophilia
IV staphylococci, streptococci, Hepatic: Jaundice Tx:
pneumococci, or other Skin: Maculopapular rash; > Dilute in 300mg in 50mL
Frequency: sensitive aerobic and urticarial solution and give over 10-60
q6 anaerobic organisms Other: Anaphylaxis minutes at no more than
30mg/minute
Drug Class: Contraindication: > Check site for phlebitis
Antibiotic; Lyncomycin > May result in overgrowth in and irritation
Derivative non-susceptible organisms;
monitor for superinfection Edx:
> Use Cautiously in neonates, > Tell patient to report
and px with renal or hepatic discomfort at IV Injection
insufficiency site
> Instruct patient to report
any of the adverse reactions.
MACANLALAY, Ralph Elvin
BSN 3F-D

DRUG NAME MECHANISM OF ACTION ADVERSE EFFECTS NURSING RESPOSIBILITY

Generic Name: Synthetic derivative of lysine CNS: dizziness. Dx:
Tranexamic Acid that exerts antifibrinolytic EENT: visual > Be alert for bleeding gums, nosebleeds,
effects by blocking lysine abnormalities. or other unusual bleeding or bruising
Dose: binding sites on plasminogen CV: hypotension, that might indicate inadequate drug
1g molecules, inhibiting the thromboembolism, effects. Report signs of bleeding to the
interaction of plasminogen thrombosis. physician immediately.
Route: with formed plasmin and GI: diarrhea, > Monitor increased blood coagulation,
SIVP fibrin. Helps blood clot and nausea, including venous thrombosis
controls bleeding. vomiting. > Assess blood pressure and compare to
Frequency: INDICATIONS & normal values
q8 CONTRAINDICATIONS Tx:
Indication: > Avoid concomitant use of Tranexamic
Drug Class: Heavy Bleeding and short term Acid Injection with medical products that
Coagulation Modifier prevention in patients with are prothrombotic because concomitant use
hemophilia can further increase the risk of
thromboembolic adverse reactions
Contraindication: Edx:
> increased risk of blood > Instruct patient to report other
clotting. troublesome side effects such as severe
> a heart attack. or prolonged vision abnormalities or GI
> acute blood clot in a blood problems
vessel supplying the lungs.
heart valve disease.
MACANLALAY, Ralph Elvin
BSN 3F-D

DRUG NAME MECHANISM OF ACTION ADVERSE EFFECTS NURSING RESPOSIBILITY

Generic Name: Inhibits cell-wall CNS: Altered mental status, Dx:
Ertapenem synthesis through anxiety, asthenia, dizziness, > If patient has diarrhea
penicillin-binding fatigue, fever, headache, during therapy, collect stool
Dose: proteins insomnia specimen for culture to rule
1g INDICATIONS & CV: chest pain, edema, HTN, out CDAD
CONTRAINDICATIONS hypotension, phlebitis, swelling, > Monitor, Renal hepatic, and
Route: Indication: tachycardia, thrombophlebitis hematopoietic function during
IV > Complicated Skin or GI: Diarrhea, Abdominal pain, therapy
skin structure infection constipation, dyspepsia, nausea, Tx:
Frequency: vomiting > Reconstitute 1g vial ith 10
q24 Contraindication: GU: renal dysfunction mL of sterile water NSS, or
> IM use is Hematologic: Leukopenia, bacteriostatic for injection
Drug Class: contraindicated neutropenia, thrombocytopenia, > Infuse over 30 minutes
Antibiotic; Carbapenem > Use cautiously in px anemia, eosinophilia, coagulation > Complete infusion within 6
with CNS disorders, and abnormalities, thrombocytosis hours of reconstitution or
impaired renal function Hepatic: Jaundice refridgerate for up to 24
Metabolic: hyperkalemia, hours
hypokalemia, hyperglycemia > Incompatible with diluents
Skin: Eythema, extravasation of containing dextrose
infusion site, pain and redness, Edx:
pruritus rash > Tell Px to alert nurse for
diarrhea, or if discomfort
occurs at injection site.
 MACANLALAY, Ralph Elvin
BSN 3F-D

DRUG NAME MECHANISM OF ACTION ADVERSE EFFECTS NURSING RESPOSIBILITY

Generic Name: Produce analgesia by inhibiting CNS: Agitation, anxiety, Dx:
Paracetamol prostaglandin and other substances that fatigue, headache, insomnia, > Monitor for s/sx of liver
sensitize pain receptors. pyrexia failure
Dose: INDICATIONS & CONTRAINDICATIONS CV: HTN, hypotension, Tx:
600mg Indication: peripheral edema, periorbital > Examine vial, don’t use if
> Mild to Moderate Pain edema, tachycardia particulate matter or
Route: GI: nausea, vomiting, abdominal discoloration is observed
IV Contraindication: pain, diarrhea, constipation > May administer without
> Use cautiously in patient with hepatic GU: oliguria further dilution
Frequency: and renal impairments Hematologic: hemolytic anemia > Incompatible with diazepam,
q6 x RTC Hepatic: Jaundice chlorpromazine hydrochloride
Metabolic: hypoalbuminemia, Edx:
Drug Class: hypoglycemia, hypokalemia, > Warn patient to not be
Analgesic; Para- hypervolemia, hypomagnesemia, dependent for pain relief,
aminophenol hypophosphatemia may cause liver impairments
derivative MS: muscle spasms, extremity
pain
Respiratory: abnormal breath
sounds, dyspnea, hypoxia,
atelectasis, pleural effusion,
pulmonary edema
 MACANLALAY, Ralph Elvin
BSN 3F-D

DRUG NAME MECHANISM OF ACTION ADVERSE EFFECTS NURSING RESPOSIBILITY

Generic Name: Binds to opioid receptors CNS: dizziness, headache, somnolence, Dx:
Tramadol and inhibits reuptake or vertigo, seizure, anxiety, asthenia, > Reassess patient level of Pain
norepinephrine and CNS stimulation, confusion, at least 30mins after
Dose: serotonin. coordination disturbance, euphoria, administration
50mg INDICATIONS & malaise, nervousness, sleep disorder, > Monitor CV and Respiratory
CONTRAINDICATIONS fever, paresthesia, tremor, Status
Route: Indication: depression, agitation, apathy > Monitor Bowel and Bladder
IV > Moderate to Moderately CV: Vasodilation, HTN, Peripheral Function
severe chronic pain Edema > Monitor for Seizures
Frequency: EENT: Visual Disturbances, > Monitor for Drug Dependency
q8 then PRN for moderate Contraindication: nasopharyngitis, pharyngitis, Tx:
to severe pain > C/I in px with GI rhinitis, sinusitis > Give drug before onset of
obstruction GI: Constipation, nausea, vomiting, intense pain
Drug Class: > C/I with concomitant use anorexia, diarrhea, dry mouth, > Taper and check for signs of
Analgesics; Synthetic or within 14 days therapy dyspepsia, flatulence withdrawal
centrally active of MAOI GU: UTI, Frequent urination > May Increase Creatinine, GGT,
analgesic; > C/I in px with Metabolic: Weight loss and Liver Enzyme Levels
respiratory depression or MS: Hypertonia, arthralgia, neck > May Decrease Hb Levels
Controlled Substance hypercania pain, myalgia Edx:
Schedule: > May put px at risk for Respiratory: Bronchitis, respiratory > Caution ambulatory patient to
IV over sedation if history depression be careful when rising and
of sleep apnea Skin: Diaphoresis, Pruritus rash walking
Other: Chills, withdrawal syndrome
MACANLALAY, Ralph Elvin
BSN 3F-D

DRUG NAME MECHANISM OF ACTION ADVERSE EFFECTS NURSING RESPOSIBILITY

Generic Name: Stimulates motility of upper CNS: Anxiety, drowsiness, Dx:
Metoclopramide GI tract, increase lower fatigue, lassitude, > Monitor Bowel Sounds
esophageal sphincter tone, restlessness, seizures, > Monitor for adverse effects
Dose: and blocks dopamine receptors akathisia, confusion, Tx:
10mg at the chemoreceptor trigger depression, dizziness, > Compatible with D5W, NSS,
zone extrapyramidal symptoms, D5NSS, and LRS for injection
Route: INDICATIONS & fever, hallucinations, > Incompatible with
IV CONTRAINDICATIONS headache, insomnia, tardive Cephalothin, chloramphenicol,
Indication: dyskinesia sodium bicarbonate
Frequency: > Prevent or reduce Nausea CV: Bradychardia, Edx:
q8 x PRN for N/V and Vomiting supraventricular tachycardia, > Tell patient to avoid
hypotension, transient HTN activities that require
Drug Class: Contraindication: GI: bowel disorders, alertness for 2 hours after
GI Stimulant; Dopamine > C/I in patient whom diarrhea, nausea dose
Antagonist stimulation of GI motility GU: incontinence > urge patient to report
might be dangerous Hematologic: agranulocytosis, persistent or serious adverse
(hemorrhage, obstruction, or neutropenia reactions promptly
perforation) Skin: Rash, Uticaria > Advise patient not to drink
Other: Loss of Libido, alcohol during therapy
prolactin secretion,
gynecomastia, amenorrhea