Forchem Chapter 6
Forchem Chapter 6
Forchem Chapter 6
What is a drug?
It is any substance (with the exception of food and water) which, when taken into the body, alters the body’s function either
physically and/or psychologically.
Dosage/Dose
it is the amount of drug taken at one time
Type of Dosage
a. Minimal – it refers to the amount needed to treat or heal, that is, the smallest amount of drug that will produce a therapeutic
effect.
b. Maximal – it pertains to the largest amount of drug that will produce a desired therapeutic effect, without any accompanying
symptoms of toxicity.
c. Toxic - it is the amount of drug that produces untoward effects or symptoms of poisoning.
d. Abusive – the amount needed to produce the side effects and action desired by an individual who improperly uses it.
e. Lethal– the amount of drug that will cause death.
Toxicology
- the science of poisons, their effects and antidotes.
a. Orally-This is the safest, most convenient and economical route whenever possible. The drug is taken by the mouth and must pass
through the stomach before being absorbed in the bloodstream. This is the most common ways of taking drugs.
b. Inhalation -A drug in gaseous form enters the lungs and is quickly absorbed by the capillary system. It is probably the second most
commonly employed drug administration.
c. Injection -Drug is administered to the body by the use of syringe or hypodermic needle in the following ways:
•Subcutaneous – the drug is injected just below the surface of the skin. This is sometimes called as “skin popping”.
•Intramuscular – administration involves the injection of a drug into a large muscle mass that has a good blood supply, such as the
gluteus maximus, quadriceps or triceps.
•Intravenous – this is the most efficient means of administration which involves depositing a drug directly to the blood stream. This is
also the most rapid drug administration.
d. Snorting / Insufflation- Inhalation of drugs through the nose. It is done by inhaling a powder or a liquid drug into the nasal coats of the
mucous membrane.
e. Buccal- Drug is placed in the buccal cavity just under the lips. The active ingredients of the drug are absorbed in the blood stream
through the soft tissues lining the mouth.
f. Suppositories- Drug is administered through the vagina or rectum in a suppository form and the drug is absorbed into the blood stream.
g. Topical- This refers to the application of drugs directly to a body site such as the mucous membrane.
Dangerous drugs
These are drugs that are attended by risk and therefore unsafe, perilous, and hazardous to people using it.
These are strictly prohibited that possession of them is punishable.
Pharmacology
simply means as the study of how a drug affects the body.
Opium
It is extracted from the coagulated juice poppy plant
Meconic Acid is the active ingredient and analgesic property of Opium.
Derivatives of Opium
Morphine – principal derivative of opium
Heroin – second derivative and the most addicting opium derivative
Codeine - A derivative of morphine commonly available in cough preparations
STIMULANTS (UPPERS)
These are drugs that produce excitation, alertness, and wakefulness, intense feeling of “highness” and in some cases, a temporary
rise in blood pressure and respiration.
It works by increasing the activity of the brain chemicals dopamine and norepinephrine. Dopamine is involved in the
reinforcement of rewarding behaviors. Norepinephrine affects blood vessels, blood pressure and heart rate, blood sugar, and
breathing.
Cocaine, Amphetamines, Methamphetamine Hydrochloride, Flakka, Caffeine
DEPRESSANTS (DOWNERS)
These are drugs which suppress vital body functions especially those of the brain or central nervous system with the resulting
impairment of judgment, hearing, speech, and muscular coordination.
They dull the minds, slow down body reactions to such an extent that accidental deaths/or suicides, usually happen.
Barbiturates, Methaqualone, Mandrax, Tranquilizers
Alcohol - It is considered as the ‘king’ of all drugs and most extensively legalized drugs throughout the world
Inhalants - The inhalation of solvent fumes from glue, gasoline, and paint thinner and lighter fluid will produce a form of intoxication.
HALLUCINOGENS (PSYCHEDELIC)
A variety or mind- altering drugs which distort reality, thinking and perception of time, sound, space and sensation. It usually
affects the user by Hallucination, Illusion and Delusion.
Hallucinogens interfere with the action of the brain chemical serotonin, which regulates mood, sensory, and perception.
Cannabis Sativa / Marijuana, Lysergic Acid Diethylamide (LSD), Mescaline, Psilocybin, Ecstasy, Phencyclidine (PCP)
Synesthesia experiencing one of your senses through another. e.i. hear colors or see sounds.