Toluene SDS
Toluene SDS
Toluene SDS
Toluene
Version 1.3 Revision Date: 03/06/2015
GHS Classification
Flammable liquids : Category 2
Hazard pictograms :
Carcinogenicity:
Emergency Overview
Appearance liquid
Hazardous components
CAS-No. Chemical Name Concentration (%)
108-88-3 Toluene 90 - 100
Specific hazards during : Do not allow run-off from fire fighting to enter drains
firefighting or water courses.
Methods and materials : Contain spillage, and then collect with non-
for containment and combustible absorbent material, (e.g. sand, earth,
cleaning up diatomaceous earth, vermiculite) and place in con-
tainer for disposal according to local / national regula-
tions (see section 13).
expo-
sure
ceases)
Personal protective equipment
Respiratory protection : No personal respiratory protective equipment normally
required.
In the case of vapour formation use a respirator with
an approved filter.
Hand protection
Remarks : The suitability for a specific workplace should be dis-
cussed with the producers of the protective gloves.
Appearance : liquid
pH : not applicable
butyl acetate=1
Flammability (solid, gas) : No data available
Solubility(ies)
Water solubility : soluble
Acute toxicity
Product:
Acute oral toxicity : Acute toxicity estimate : > 5,000 mg/kg
Method: Calculation method
Components:
108-88-3:
Acute oral toxicity : LD50 (rat, male): > 5,580 mg/kg
Acute inhalation toxicity : LC50 (rat, male and female): 28.1 mg/l
Exposure time: 4 h
Test atmosphere: vapour
Method: OECD Test Guideline 403
Skin corrosion/irritation
Product:
Result: Irritating to skin.
Components:
108-88-3:
Species: rabbit
Exposure time: 4 h
Result: Irritating to skin.
Product:
Result: Irritating to eyes.
Components:
108-88-3:
Species: rabbit
Components:
108-88-3:
Test Type: Maximisation Test (GPMT)
Species: guinea pig
Result: Did not cause sensitisation on laboratory animals.
GLP: yes
Components:
108-88-3:
Genotoxicity in vitro : Test Type: Mammalian cell gene mutation assay
Test species: Mouse lymphoma cells
Metabolic activation: with and without metabolic acti-
vation
Method: OECD Test Guideline 476
Result: negative
Germ cell mutagenicity- : Tests on bacterial or mammalian cell cultures did not
Assessment show mutagenic effects.
Carcinogenicity
Components:
108-88-3:
Species: rat, (male and female)
Application Route: inhalation (vapour)
Exposure time: 103 wks
Dose: 0, 600, 1200 ppm
Frequency of Treatment: 6.5 h/d, 5 d/wk
NOAEL: No observed adverse effect level: 1,200 ppm
Reproductive toxicity
Components:
108-88-3:
Effects on fertility : Test Type: Two-generation study
Species: rat, male and female
Application Route: Inhalation
Dose: 0, 100, 500, 2000 ppm
Frequency of Treatment: 7 days/week
General Toxicity - Parent: NOAEC: 500 ppm
General Toxicity F1: NOAEC: 500 ppm
Fertility: NOAEC: 2,000 ppm
Symptoms: Reduced maternal body weight gain. Re-
duced offspring weight gain.
Method: OECD Test Guideline 416
Result: Animal testing did not show any effects on
fertility.
GLP: yes
Components:
108-88-3:
Exposure routes: Target Organs: Assessment: Remarks:
Inhalation Auditory system, May cause damage
Eyes to organs through
prolonged or re-
peated exposure.,
The substance or
mixture is classified
as specific target
organ toxicant, re-
peated exposure,
category 2.
Components:
108-88-3:
Species: rat, male and female
NOAEL: 300
Application Route: inhalation (vapour)
Exposure time: 6, 12, or 18 mths
Number of exposures: 6 h/d, 5 d/wk
Dose: 0, 30, 100, 300 ppm
Method: OECD Test Guideline 453
Aspiration toxicity
Product:
May be fatal if swallowed and enters airways.
Components:
108-88-3:
Aspiration Toxicity - Category 1
Further information
Product:
Remarks: Symptoms of overexposure may be headache, dizziness, tiredness, nau-
sea and vomiting., Concentrations substantially above the TLV value may cause nar-
cotic effects., Solvents may degrease the skin.
Ecotoxicity
Components:
108-88-3:
Toxicity to fish : LC50 (Oncorhynchus mykiss (rainbow trout)): 5.5
mg/l
Exposure time: 96 h
Test Type: flow-through test
Ecotoxicology Assessment
Acute aquatic toxicity : Toxic to aquatic life.
Chronic aquatic toxicity : Toxic to aquatic life with long lasting effects.
Components:
108-88-3:
Biodegradability : Inoculum: Sewage
Biodegradation: 100 %
Remarks: Readily biodegradable
Bioaccumulative potential
Components:
108-88-3:
Partition coefficient: n- : log Pow: 2.73
octanol/water
Mobility in soil
No data available
Other adverse effects
No data available
Product:
Regulation 40 CFR Protection of Environment; Part 82 Protection
of Stratospheric Ozone - CAA Section 602 Class I Sub-
stances
Remarks This product neither contains, nor was manufactured
with a Class I or Class II ODS as defined by the U.S.
Clean Air Act Section 602 (40 CFR 82, Subpt. A, App.A
+ B).
Disposal methods
Waste from residues : Dispose of in accordance with all applicable local,
state and federal regulations.
For assistance with your waste management needs -
including disposal, recycling and waste stream reduc-
tion, contact NEXEO's Environmental Services Group
at 800-637-7922.
drum.
The following chemical(s) are listed as HAP under the U.S. Clean Air Act, Section 12
(40 CFR 61):
108-88-3 Toluene 100 %
100-41-4 Ethylbenzene 0.0999 %
71-43-2 Benzene 0.0999 %
98-82-8 Cumene 0.0004 %
This product does not contain any chemicals listed under the U.S. Clean Air Act
Section 112(r) for Accidental Release Prevention (40 CFR 68.130, Subpart F).
The following chemical(s) are listed under the U.S. Clean Air Act Section 111 SOCMI
Intermediate or Final VOC's (40 CFR 60.489):
108-88-3 Toluene 100 %
100-41-4 Ethylbenzene 0.0999 %
71-43-2 Benzene 0.0999 %
98-82-8 Cumene 0.0004 %
Clean Water Act
The following Hazardous Substances are listed under the U.S. CleanWater Act, Sec-
tion 311, Table 116.4A:
108-88-3 Toluene 100 %
100-41-4 Ethylbenzene 0.0999 %
71-43-2 Benzene 0.0999 %
The following Hazardous Chemicals are listed under the U.S. CleanWater Act, Section
311, Table 117.3:
108-88-3 Toluene 100 %
100-41-4 Ethylbenzene 0.0999 %
71-43-2 Benzene 0.0999 %
This product contains the following toxic pollutants listed under the U.S. Clean Water
Act Section 307
108-88-3 Toluene 100 %
US State Regulations
reproductive harm.
108-88-3 Toluene
71-43-2 Benzene
Further information
HEALTH 2*
3
Instability
Health
2 0 FLAMMABILITY 3
PHYSICAL HAZARD 0
The information accumulated is based on the data of which we are aware and is
believed to be correct as of the date hereof. Since this information may be ap-
plied under conditions beyond our control and with which we may be unfamiliar
and since data made become available subsequently to the date hereof, we do
not assume any responsibility for the results of its use. Recipients are advised to
confirm in advance of need that the information is current, applicable, and suita-
ble to their circumstances. This MSDS has been prepared by NEXEO™ Solutions
EHS Product Safety Department (1-855-429-2661) MSDS@nexeosolutions.com.
Material number:
16076583, 20054, 16052078, 16044492, 16042922, 16020146, 758386, 744411,
744290, 710730, 710841, 659495, 638920, 605418, 599094, 591594, 583688,
577548, 74292, 554035, 554297, 554199, 554034, 550273, 547202, 508613,
508487, 102358, 87255, 86312, 53763, 87252, 102690, 70140, 85974, 53211,
54494, 53551, 86521, 53216, 69928, 102899, 69593, 103631, 54061, 70083,
86461, 102680, 53543, 69918, 85966, 53699, 127683, 508226, 508225, 503157,
502489, 500113, 500040, 20058, 20055, 20052, 20051, 20050, 20049, 508283
Key or legend to abbreviations and acronyms used in the safety data sheet
ACGIH American Conference of Gov- LD50 Lethal Dose 50%
ernment Industrial Hygienists
AICS Australia, Inventory of Chem- LOAEL Lowest Observed Adverse Effect
ical Substances Level
DSL Canada, Domestic Sub- NFPA National Fire Protection Agency
stances List
NDSL Canada, Non-Domestic Sub- NIOSH National Institute for Occupational
stances List Safety & Health
CNS Central Nervous System NTP National Toxicology Program
CAS Chemical Abstract Service NZloC New Zealand Inventory of Chemicals
EC50 Effective Concentration NOAEL No Observable Adverse Effect Level
EC50 Effective Concentration 50% NOEC No Observed Effect Concentration
EGEST EOSCA Generic Exposure OSHA Occupational Safety & Health Admin-
Scenario Tool istration
EOSCA European Oilfield Specialty PEL Permissible Exposure Limit
Chemicals Association
EINECS European Inventory of Exist- PICCS Philipines Inventory of Commercial
ing Chemical Substances Chemical Substances
MAK Germany Maximum Concen- PRNT Presumed Not Toxic
tration Values
GHS Globally Harmonized System RCRA Resource Conservation Recovery Act
>= Greater Than or Equal To STEL Short-term Exposure Limit
IC50 Inhibition Concentration 50% SARA Superfund Amendments and Reau-
thorization Act.
IARC International Agency for Re- TLV Threshold Limit Value
search on Cancer
IECSC Inventory of Existing Chemi- TWA Time Weighted Average
cal Substances in China
ENCS Japan, Inventory of Existing TSCA Toxic Substance Control Act
and New Chemical Sub-
stances
KECI Korea, Existing Chemical In- UVCB Unknown or Variable Compositon,
ventory Complex Reaction Products, and
Biological Materials
<= Less Than or Equal To WHMIS Workplace Hazardous Materials In-
formation System
LC50 Lethal Concentration 50%