OU - 1704 OU - 1704: Faculty of Pharmacy
OU - 1704 OU - 1704: Faculty of Pharmacy
OU - 1704 OU - 1704: Faculty of Pharmacy
D-8258/PCI
FACULTY OF PHARMACY
B. Pharmacy VII-Semester (PCI) (Backlog) Examination, August 2022
Subject: Industrial Pharmacy
Time: 3 Hours Max. Marks: 75
Note: Answer all questions PART – A, any two questions from PART – B
and any seven question from PART – C.
PART – A (10 x 2 = 20 Marks)
1 Write a note on SUPAC.
2 What is validation?
3 Write a note on DQ, IQ, OQ and PQ.
4 What is QRM?
5 Define API and excipient.
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6 What are various phases of clinical trials?
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7 What is the aim of NDA?
8 Define Bioavailability and Bioequivalence.
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9 Write a note on CDSCO.
10 What is RDTL and its functions?
PART – B (2 x 10 = 20 Marks)
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11 (a) Write the General considerations for pilot plant and scale up.
(b) Write a note on platform technology.
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13 (a) Discuss Regulatory requirements and approval procedures for New Drugs.
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PART – C (7 x 5 = 35 Marks)
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14 Explain the procedure for pilot plat scale-up for semisolid dosage forms.
O
Note: Answer all questions PART – A, any two questions from PART – B
and any seven question from PART – C.
4
4. Name the Infra-Red radiation source.
70
5. Define the term chromatography and the general principle involved in it.
6. Mention the factors affecting Electrophoretic Mobility.
7. Write about the temperature program in Gas chromatography.
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8. Explain different types of pumps used in HPLC and their brief working principle.
9. Explain the principle involved in Ion Exchange Chromatography.
10. Write the theory involved in Gel Chromatography.
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PART – B (2 x 10 = 20 Marks)
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11. (a) Explain in detail about the construction and working principle of detectors
used in UV-Vis spectroscopy.
(b) Write about the Methodology involved in Paper Chromatography.
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chromatography.
13. (a) Explain the applications of HPLC with examples.
(b) Write about the Instrumentation of Affinity chromatography.
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PART – C (7 x 5 = 35 Marks)
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Code No. D-8260/PCI
FACULTY OF PHARMACY
B. Pharmacy VII - Semester (PCI) (Backlog) Examination, September 2022
Subject: Novel Drug Delivery Systems
Time: 3 Hours Max. Marks: 75
PART – A
Note: Answer all questions. (10 x 2 = 20 Marks)
4
4. Explain the Nasal and Pulmonary routes of drug delivery.
5. Write the advantages and disadvantages of gastroretentive drug delivery system.
70
6. Explain various coating materials used in microencapsulation.
7. Write a note on transmucosal permeability.
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8. What is floating time and floating lag time.
9. Write the applications of monoclonal antibodies.
10. Compare and contrast liposomes and niosomes.
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PART – B
O
Note: Answer any two questions. (2 x 10 = 20 Marks)
11. Explain in detail physiochemical and biological factors affecting controlled release
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formulations.
12. Explain in detail coacervation phase separation method with suitable examples.
70
13. Discuss about advantages and disadvantages and development of intra uterine
devices and applications.
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PART – C
Note: Answer any seven questions. (7 x 5 = 35 Marks)
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14. Discuss the classification and applications of polymers used in controlled drug
delivery system.
O
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Code No. D-8259/PCI
FACULTY OF PHARMACY
B. Pharmacy VII-Semester (PCI) (Backlog) Examination, September 2022
Subject: Pharmacy Practice
Time: 3 hours Max Marks: 75
PART - A
Note: Answer all the questions. (10 x 2 = 20 Marks)
4
5. Mention few examples of pharmacokinetic drug interactions
6. Mention few drugs which require TDM
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7. Define patient counselling.
8. Define lead time.
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9. Define investigational drug.
10. Give a general patient counselling information for NSAIDs
PART - B
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Note: Answer any two questions (2 x 10 = 20 Marks)
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11. Describe different types of drug interactions. Add a note on reporting and
management of ADR
12. Describe organisation, structure, type and design of wholesale and community
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pharmacy outlet
13. Explain different types of drug distribution system in a hospital. What do you
70
14. Define hospital formulary. What are the contents of hospital formulary? What is
the difference between hospital formulary and essential drugs list?
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15. Explain the role of pharmacist in improving medication adherence and highlight
few counselling barriers.
O
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Code No. D-8182/PCI
FACULTY OF PHARMACY
B. Pharmacy VII - Semester (PCI) (Main & Backlog) Examination,
February / March 2022
PART - A
Note: Answer all questions: (10 x 2 = 20 Marks)
4
4. Write the applications of Nephelometry and turbidometry techniques.
70
5. Write different types of stationary phase column packing materials used in HPLC.
6. Write Van Deempter equation.
7. What are the different types of Ion exchange resins used in Ion-exchange
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chromatography?
8. Define theoretical plate and give formula for calculating theoretical plates.
9. What is an electronic transition and types?
10. Write the principle involved in affinity chromatography.
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PART - B
Note: Answer any two questions: (2 x 10 = 20 Marks)
12. Explain the principles and experimental details of paper chromatography for
70
Quantitative analysis.
13. Explain the principles and instrumentation of Gas chromatography technique.
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PART - C
Note: Answer any seven questions: (7 x 5 = 35 Marks)
15. Describe different methods for quantitative analysis of single component samples
by UV spectrophotometry.
O
16. Explain the principles, advantages and disadvantages and applications of thin
layer chromatography.
17. Write about Gel Permeation chromatography.
18. Write the principles and applications of Atomic absorption spectroscopy.
19. Explain different sample handling techniques used in IR spectroscopy.
20. Explain the principles of fluorescence and Phosphorescence with help of
Joblonski diagram.
21. Explain the principles and applications of partition and adsorption
chromatography.
22. Write the different factors affecting electrophoretic mobility of ions in
electrophoresis separations.
*****
Code No. D-8183/PCI
FACULTY OF PHARMACY
B. Pharmacy VII - Semester (PCI) (Main & Backlog) Examination,
February / March 2022
4
2 Write the level of changes expected under SUPAC.
70
3 Explain the quality risk management to technology transfer.
4 Describe the role of project team in the technology transfer.
5 Enlist at least four names of regulatory authorities functioning all around the
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world.
6 Enumerate the categories and type of INDs.
7 What are the benefits of NABL accreditation?
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8 Mention the difference between corrective actions and preventive actions in
quality system.
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9 Write the functions of state regulatory authority.
10 What are the regulatory requirements for new drug approval?
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PART - B
70
PART - C
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FACULTY OF PHARMACY
B. Pharmacy VII - Semester (PCI) (Main & Backlog) Examination,
February / March 2022
PART - A
Note: Answer all questions: (10 x 2 = 20 Marks)
4
pharmacy.
70
4. Describe the significance of Drug Information Center.
5. Explain the important considerations for Therapeutic Drug Monitoring.
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6. Give a brief note on the factors affecting drug variability.
7. Write a short note on material requirement for community pharmacy.
8. Give definition of drug integrations and classify them accordingly.
9. Enumerate the types of drug ADRs with examples.
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10. Write a note on rational use of drugs.
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PART - B
Note: Answer any two questions: (2 x 10 = 20 Marks)
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11. Define P & T Committee and write its objectives, organization and various
functions.
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12. Define Hospital and enumerate the organization and functions of hospital.
13. What is meant by clinical pharmacy? Explain functions and responsibility of
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clinical pharmacy.
PART - C
Note: Answer any seven questions: (7 x 5 = 35 Marks)
U
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Code No. D-8185/PCI
FACULTY OF PHARMACY
B. Pharmacy VII-Semester (PCI) (Main & Backlog) Examination,
February / March 2022
PART - A
Note: Answer all questions: (10 x 2 = 20 Marks)
4
2. Enlist ideal characters suitable for selection of drug for controlled drug delivery
system.
70
3. Define microencapsulation, write its applications.
4. What are implantable drug delivery system with examples?
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5. Write the advantages and disadvantages of mucoadhesive drug delivery system.
6. Explain various coating materials used in microencapsulation.
7. Write a note on permeation enhancers with examples.
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8. What is floating time and floating lag time?
9. Write the applications of monoclonal antibodies.
O
10. Write the methods of evaluation of liposomes.
PART - B
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PART - C
Note: Answer any seven questions: (7 x 5 = 35 Marks)
O
14. Discuss the classification and applications of polymers used in controlled drug
delivery system.
15. Explain the theories of mucoadhesion.
16. Write a note on osmotic pump.
17. Discuss the approaches used in development of gastroretentive drug delivery
system.
18. Explain about nasal sprays and nebulizers.
19. Write a note on niosomers.
20. Discuss the ocuserts with neat sketch.
21. Explain the applications of intrauterine devices.
22. Explain the formulation considerations of buccal drug delivery system.
*****
Code No. 12332/PCI
FACULTY OF PHARMACY
B. Pharmacy VII-Semester (PCI) (Backlog) Examination,
September 2021
Subject: Instrumental Method of Analysis
Time: 2 Hours Max. Marks: 75
PART – A
Note: Answer any seven questions. (7 X 3 = 21 Marks)
PART – C
Note: Answer any five questions. (5 X 8 = 40 Marks)
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Code No.12333/PCI
FACULTY OF PHARMACY
B. Pharmacy VII-Semester (PCI) (Backlog) Examination,
September 2021
Subject: Industrial Pharmacy - II
PART – A
Note: Answer any seven questions. (7 X 3 = 21 Marks)
14. Explain the procedure for pilot plant scale-up for liquid dosage form.
15. What is technology transfer? Write general principles of Technology Transfer.
16. Write the role of regulatory affairs department in drug approval.
17. What is QRM? Describe the principle and process of QRM.
18. Write briefly on Master Formula Record and its importance.
19. Write a note on ICH guidelines.
20. Explain about Central Drugs Laboratory and its function.
21. Write brief note on (i) IND (ii) NDA.
22. Write protocol for technology transfer.
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Code No.12334/PCI
FACULTY OF PHARMACY
B. Pharmacy VII-Semester (PCI) (Backlog) Examination,
September 2021
Subject: Pharmacy Practice
Time: 2 Hours Max. Marks: 75
PART – A
Note: Answer any seven questions. (7 X 3 = 21 Marks)
PART – B
Note: Answer any one questions. (1 X 14 = 14 Marks)
11. Define Therapeutic Drug Monitoring (TDM). Mention its objectives and
explain the process involved in TDM.
12. (a) Explain in detail the objectives of Pharmacy and Therapeutic
Committee (PTC).
(b) Discuss the role of PTC in adverse drug monitoring.
13. Define Clinical Pharmacy. Explain in detail the functions and
responsibilities of clinical pharmacist.
PART – C
Note: Answer any five questions. (5 X 8 = 40 Marks)
*******
Code No.12335/PCI
FACULTY OF PHARMACY
B. Pharmacy VII-Semester (PCI) (Backlog) Examination,
September 2021
Subject: Novel Drug Delivery Systems
Time: 2 Hours Max. Marks: 75
PART – A
Note: Answer any seven questions. (7 X 3 = 21 Marks)
PART – B
Note: Answer any one questions. (1 X 14 = 14 Marks)
11. Discuss the formulation of Transdermal drug delivery systems with the
components and examples? Add a note on factors affecting permeation?
12. Write in detail about the coacervation phase separation technique with
examples?
13. Write in detail about the following:
(a) Explain about the Alzet osmotic pump?
(b) Mucoadhesive drug delivery system?
PART – C
Note: Answer any five questions. (5 X 8 = 40 Marks)
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Code No. 12224/PCI
FACULTY OF PHARMACY
B. Pharmacy VII-Semester (PCI) (Main) Examination, March 2021
PART – A
Note: Answer any seven questions. (7 X 3 = 21 Marks)
1. Define chromophore and Auxochrome and give examples.
2. Explain the phenomenon of Fluorescence and Phosphorescence.
3. What are the different types of fundamental modes of vibration in molecules after
absorption of IR radiations?
4. Write the principles of partition and adsorption chromatography.
5. Write the different fuel gases and oxidants used in flame photometry technique.
6. Write the applications of gel permeation chromatography.
7. Write the ion exchange mechanism of ion exchange chromatogramphy.
8. Define retardation factor.
9. What is Bathochromic and Hypsochromic shift?
10. Write the principle involved in affinity chromatography.
PART – B
Note: Answer any one questions. (1 X 14 = 14 Marks)
11. Describe different components of UV spectrophotometer with a labeled
diagram.
12. Explain the principles and experimental detail of thin layer chromatography
for Quantitative analysis.
13. Explain the principles and instrumentation of HPLC technique.
PART – C
Note: Answer any five questions. (5 X 8 = 40 Marks)
***
Code No.12227/PCI
FACULTY OF PHARMACY
B. Pharmacy VII-Semester (PCI) (Main) Examination, March 2021
PART – A
Note: Answer any seven questions. (7 X 3 = 21 Marks)
PART – B
Note: Answer any one question. (1 X 14 = 14 Marks)
11. Explain the approaches used in development of gastro retentive drug delivery systems.
12. Explain in detail coacervation phase separation with suitable examples.
13. Discuss classification, properties and applications of polymers used in controlled drug delivery
system.
PART – C
Note: Answer any five questions. (5 X 8 = 40 Marks)
14. Discuss the physicochemical factors affecting controlled drug delivery system.
15. Explain the principles of mucoadhesion.
16. Write a note on metered dose inhaler.
17. Discuss the basis used in development of transdermal drug delivery system.
18. Explain about intra-uterine devices.
19. Write about production of monoclonal antibodies.
20. Discuss the ocular barriers, methods to overcome barriers.
21. Explain the approaches used in development of controlled drug delivery systems.
22. Explain the formulation considerations of buccal drug delivery system.
***
Code No. 12226/PCI
FACULTY OF PHARMACY
B. Pharmacy VII-Semester (PCI) (Main) Examination, March 2021
PART – A
Note: Answer any seven questions. (7 X 3 = 21 Marks)
PART – B
Note: Answer any one question. (1 X 14 = 14 Marks)
11. Define hospital formulary and elaborate the stepwise procedure involved
in the preparation of hospital formulary.
12. What is clinical pharmacy? Elucidate functions and responsibility of clinical pharmacy.
13. Give a detailed account on the factors affecting Therapeutic Drug Monitoring.
PART – C
Note: Answer any five questions. (5 X 8 = 40 Marks)
PART – A
Note: Answer any seven questions. (7 X 3 = 21 Marks)
PART – B
Note: Answer any one question. (1 X 14 = 14 Marks)
11. Explain the process of Change control with the help of flow-chart.
12. Discuss the NDA approval process in detail, illustrate with the help of flow
diagram.
13. Explain the features of finished product technology transfer as per WHO
guidelines.
PART – C
Note: Answer any five questions. (5 X 8 = 40 Marks)
***