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    Department of Education

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    Chzaren An Louise Gatus
    This document contains instructions for a performance task on the Hardy-Weinberg equation for Grade 11 STEM students of the Cabanatuan City Senior High School. Students are asked to apply the Hardy-Weinberg equation to solve a word problem about the inheritance of Gaucher disease. They must show their work, explanations, and understanding on the provided sheet and be evaluated based on a rubric assessing content, style, originality, and punctuality.

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    Department of Education

    Uploaded by

    Chzaren An Louise Gatus
    27 views4 pages
    This document contains instructions for a performance task on the Hardy-Weinberg equation for Grade 11 STEM students of the Cabanatuan City Senior High School. Students are asked to apply the Hardy-Weinberg equation to solve a word problem about the inheritance of Gaucher disease. They must show their work, explanations, and understanding on the provided sheet and be evaluated based on a rubric assessing content, style, originality, and punctuality.

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    This document contains instructions for a performance task on the Hardy-Weinberg equation for Grade 11 STEM students of the Cabanatuan City Senior High School. Students are asked to apply the Hardy-Weinberg equation to solve a word problem about the inheritance of Gaucher disease. They must show their work, explanations, and understanding on the provided sheet and be evaluated based on a rubric assessing content, style, originality, and punctuality.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    27 views4 pages

    Department of Education

    Uploaded by

    Chzaren An Louise Gatus
    This document contains instructions for a performance task on the Hardy-Weinberg equation for Grade 11 STEM students of the Cabanatuan City Senior High School. Students are asked to apply the Hardy-Weinberg equation to solve a word problem about the inheritance of Gaucher disease. They must show their work, explanations, and understanding on the provided sheet and be evaluated based on a rubric assessing content, style, originality, and punctuality.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 4

    Republic of the Philippines

    Department of Education
    Region III
    Schools Division of Cabanatuan City
    CABANATUAN CITY SENIOR HIGH SCHOOL
    Emilio Vergara Highway, Sta. Arcadia, Cabanatuan City

    GENERAL BIOLOGY 2
    PERFORMANCE TASK 4
    GRADE 11 STEM
    Date of Submission: March 22, 2023

    a. Individual Task
    b. Students will perform Activity 13.1 (p. 7, ADM No. 7) entitled “Hardy-Weinberg
    Equation”.
    c. Apply the theory of Hardy-Weinberg Equation mentioned in ADM No. 6, page 9.
    d. Use this sheet for your answer and explanations. Follow the directions of this
    activity posted below:

    ACTIVITY 13.1: Word Problem


    Directions: Solve using the Hardy-Weinberg equation.
    Gaucher disease (GD) is a lysosomal storage disorder caused by the deficiency of the β-
    glucocerebrosidase enzyme due to disease causing mutations in the GBA1 (glucosidase
    beta acid) gene.This leads to the abnormal accumulation of the lipid glucocerebroside in
    lysosomal macrophages. GD is a rare genetically inherited trait that is expressed in the
    phenotype of homozygous recessive individuals (aa). The average human frequency of the
    disease in the Philippines is only about 1 in 20,000.

    A=0.993 a=0.007
    1
    AA=0.986 Aa= 0.014 aa= 2000

    Solution:

    P2+22pq+q2=1 Hardy-Weinberg Equation


    1
    q2= 2000 q=0.007

    p=0.993 P2=0.986

    2pq= 2(0.993)(0.007)

    = 0.014
    e. Write your explanations and understanding on the spaces below:

    Address : Emilio Vergara Highway, Sta. Arcadia, Cabanatuan City


    School ID No. : 305633
    Email Address : lady.bayan@deped.gov.ph
    Republic of the Philippines
    Department of Education
    Region III
    Schools Division of Cabanatuan City
    CABANATUAN CITY SENIOR HIGH SCHOOL
    Emilio Vergara Highway, Sta. Arcadia, Cabanatuan City

    I employed the Hardy-Weinberg Equation to determine the homozygous


    dominant, heterozygous, and homozygous recessive. I used the stated
    ratio to obtain the q2, and then square-rooted the q2 to determine the
    frequency of the recessive allele. I then calculate the dominant allele
    frequency by subtracting the recessive allele frequency from 1. Then, I
    multiply the recessive allele frequency and the dominant allele frequency
    by two to obtain the heterozygous.

    f. Student must submit this by following these required modes and steps:
    1.) This sheet with the answers on the box being provided, to be submitted
    together with the page for explanation.
    2.) Use the rubrics below:

    Rubrics 1 Over-all Impression / Styles/


    Level Punctuality Content Originality
    It follows the directions Very much original in
    Output is answered more and has well-organized explanation and not
    Excellent convincingly and clearly factual ideas. With at copied from the website
    (10) and submitted on time. least five (5) or from the answer key.
    authoritative references
    or factual bases.
    Somewhat clear on the Some explanation or
    Output is answered but ideas but still follows ideas are shifted from
    Good lacking enough reasoning directions. reliable sources but with
    (7) and submitted on time. With at least three (3) personal explanation of
    authoritative references the surrounding facts.
    or factual bases.
    Not clear on his/her Most of the ideas or
    Fair Output lacks convincing ideas but still follows answers have been
    (5) explanation and submitted directions, with at least copied. Not original or
    1-2 days late two (2) authoritative own perspective.
    references or factual
    bases.
    Does not follow
    Needs Improvement Output does not contain directions and ideas not Output does not reflect
    (3) convincing explanation clear. any valid claim and
    and was submitted not on With zero (0) reliable answers.
    time. authoritative references
    or factual bases.

    Address : Emilio Vergara Highway, Sta. Arcadia, Cabanatuan City


    School ID No. : 305633
    Email Address : lady.bayan@deped.gov.ph
    Republic of the Philippines
    Department of Education
    Region III
    Schools Division of Cabanatuan City
    CABANATUAN CITY SENIOR HIGH SCHOOL
    Emilio Vergara Highway, Sta. Arcadia, Cabanatuan City

    Address : Emilio Vergara Highway, Sta. Arcadia, Cabanatuan City


    School ID No. : 305633
    Email Address : lady.bayan@deped.gov.ph
    Republic of the Philippines
    Department of Education
    Region III
    Schools Division of Cabanatuan City
    CABANATUAN CITY SENIOR HIGH SCHOOL
    Emilio Vergara Highway, Sta. Arcadia, Cabanatuan City

    Address : Emilio Vergara Highway, Sta. Arcadia, Cabanatuan City


    School ID No. : 305633
    Email Address : lady.bayan@deped.gov.ph

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