NCMC103 Prelims Reviewer
NCMC103 Prelims Reviewer
NCMC103 Prelims Reviewer
MICROBIAL GENETICS
● functions of DNA and RNA
INTRODUCTION TO MICROBIOLOGY
ENVIRONMENTAL MICROBIOLOGY
MAIN THEMES OF MICROBIOLOGY ● relationship between microbes and among
● the scope of microbiology microbes, other organisms, and environment
● the impact of microbes on earth: small organisms
with a giant effects APPLIED MICROBIOLOGY
● human use of microorganisms
● infectious diseases and the human condition MEDICAL MICROBIOLOGY
MICROBE-CENTERED ETIOLOGY
● cause of disease
BACTERIOLOGY
INFECTION CONTROL
● Bacteriology is the branch and specialty of biology
that studies the morphology, ecology, genetics and ● hygiene in health care settings and control of
biochemistry of bacteria as well as many other nosocomial infections
aspects related to them
CHEMOTHERAPHY
PROTOZOOLOGY ● development and use of drugs to treat infectious
● Protozoology is the study of protozoa, the diseases
"animal-like" (i.e., motile and heterotrophic) protists
APPLIED ENVIRONMENTAL MICROBIOLOGY
PHYCOLOGY
● Phycology is the science that studies all forms of BIOREMEDIATION
algae, from very tiny microorganisms that float ● use of microbes to remove pollutants
through the ocean to huge forests of seaweed.
PUBLIC HEALTH MICROBIOLOGY
PARASITOLOGY ● sewage treatment, water purification, and control of
● Parasitology is the scientific discipline concerned insects that spread diseases
with the study of the biology of parasites and
parasitic diseases AGRICULTURAL MICROBIOLOGY
● use of microbes to control insect pests
MYCOLOGY
● the study of fungi, a group that includes the FOOD AND BEVERAGE TECHONOLOGY
mushrooms and yeasts ● reduction and elimination of harmful microbes in
food and drink
VIROLOGY
● Virology is the scientific discipline concerned with PHARMACEUTICAL MICROBIOLOGY
the study of the biology of viruses and viral ● manufacture of vaccines and antibiotics
diseases, including the distribution, biochemistry,
GLOCOCALYCES
● gelatinous, sticky substance surrounding the
outside of the cell
● composed of polysaccharides, polypeptides or both
TWO TYPES:
A. Capsule
○ composed of organized repeating units of
organic materials
○ firmly attached to cell surface
○ protect cells from drying out
○ may prevent bacteria from being
recognized and destroyed by host
SUMMARY: B. Slime layer
○ loosely attached to cell surface
○ water soluble
○ protects cells from drying out
CELL CELL WALL CELL ○ sticky layer that allows prokaryotes to
TYPE MEMBRANE attach to surfaces
ARCHAE prokaryotic polysaccharid the lipid
es and membrain is
proteins, either linked,
pseudo with the
murein branching of
aliphatic acids
R-O-R
TYPE 2:
● additional layers of material are present outside the
S-later.
● In Methanosprillum, there is aprotein sheath
GRAM NEGATIVE CELL WALLS external to S-layer
● have only a thin layer of peptidoglycan
● bilayer membrane outside the peptidoglycan
contains phospholipids,proteins, and
lipopolysaccharide (LPS)
● may be independent to the treatment of disease
● appear pink following gram staining procedure
TYPE 3:
● In methanosarcina, S-layer is covered by a
chondroitin like material called as
mathanochondroitin
TYPE 5:
● in this type, S layer is absent. Instead archaeal cell
wall is single thick homogenous layer resembling
Gram positive bacteria.
● These archeae often stain gram positive
● this type is present in Methanobacterium
Halococcus etc.
CYTOPLASM OF PROKARYOTES
EXTERNAL STRUCTURES OF EUKARYOTIC
CYTOSOL CELLS
● liquid portion of cytoplasm
GLYCOCALYCES
INCLUSIONS ● Never as organized as prokaryotic capsules
● may include reserve deposits of chemicals ● Help anchor animal cells to each other
● Strengthen cell surface
● Provide protection against dehydration
ENDOSPORES ● Function in cell-to-cell recognition and
● unique structures produced by some bacteria that communication
area defensive strategy against unfavorable ●
conditions
RIBOSOMES NUCLEUS
● Larger than prokaryotic ribosomes (80S versus ● Often largest organelle in cell
70S) ● Contains most of the cell’s DNA
● Composed of 60S and 40S subunits ● Semi-liquid portion called nucleoplasm
● One or more nucleoli present in nucleoplasm; RNA
synthesized in nucleoli
CYTOSKELETON ● Nucleoplasm contains chromatin – masses of DNA
● Extensive associated with histones
● Functions ● Surrounded by nuclear envelope – double
○ Anchors organelles membrane composed of two phospholipid bilayers
○ Cytoplasmic streaming and movement of ● nuclear envelope contains nuclear pores
organelles
○ Movement during endocytosis and
amoeboid action
○ Produces basic shape of the cell
● made up of tubulin microtibules, actin
microfilaments, and intermediate filaments
ENDOPLASMIC RETICULUM
● Netlike arrangement of flattened, hollow tubules
continuous with nuclear envelope
● Functions as transport system
● Two forms
○ Smooth endoplasmic reticulum (SER) –
plays role in lipid synthesis
○ Rough endoplasmic reticulum (RER) –
ribosomes attached to its outer surface;
CENTRIOLES AND CENTROSOME transport proteins produced by ribosomes
● Centrioles and centrosome
○ Centrioles play a role in mitosis,
cytokinesis, and in formation of flagella
and cilia
○ Centrioles composed of “9 + 0”
arrangement of microtubules
○ Centrosome is region of cytoplasm where
centrioles are found
GOLGI BODY
● Receives, processes, and packages large
molecules for export from cell
● Packages molecules in secretory vesicles that fuse
with cytoplasmic membrane
● Composed of flattened hollow sacs surrounded by
phospholipid bilayer
● Not in all eukaryotic cells
MITOCHONDRIA
● Have two membranes composed of phospholipid
bilayer
● Produce most of cell’s ATP
● Interior matrix contains 70S ribosomes and circular
molecule of DNA
●
CHLOROPLASTS
● Light-harvesting structures found in photosynthetic
eukaryotes
● Have two phospholipid bilayer membranes and
DNA
● Have 70S ribosomes
SPECIAL NOTES:
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