Trabalho Final
Trabalho Final
Trabalho Final
Mini-Review
Technological Tattoos
Diogo Pires 93037 and João Machado 111331
A new technology begins to emerge, the tech tattos are here to stay. In a simple way we can measure
a big amount of different things, just like: heart beat , monitor and diagnosis critical health problems,
sleep disorders, brain activity,etc. In this review we analized and discuss two different aproaches. In
one we get the tattos by a graphene-based circuit and in the other by 3D-pritting a composite.
The design of the device can be adjusted within the specifications. The
Recent progress has shown that the graphene-based materials can offered baseline process is a GFET (Fig. 1) consisting of the following
have a profound impact on electronic and optoelectronic devices, fabrication steps:
chemical sensors, nanocomposites and energy storage. We can see
some applications of graphene-based material nowadays in figure 2. • Back Gate & Bottom contact
• Dielectric deposition
[5]The 2D Experimental Pilot Line (2D-EPL), a project grown from
• Wafer scale graphene transfer
the Graphene Flagship, has launched its first customisable wafer run
• Top Contacts and Encapsulation
targeting sensor applications. Companies, universities, and research
• Opening of encapsulation*
institutes can include their designs as dies on joint wafers, to test their
ideas for devices on a larger scale at relatively low costs. The 2D-EPL Electronic skin, a kind of flexible electronic device and system
is a €20 million project aiming to pioneer the fabrication of prototype inspired by human skin, has emerged as a promising candidate for
electronics and sensors based on graphene and related materials wearable personal healthcare applications. Wearable electronic
(GRMs), and at integrating them into established silicon devices with skin-like properties will provide platforms for
semiconductor platforms. While doing so, the project will also refine continuous and real-time monitoring of human physiological signals
and scale up the manufacturing process of graphene-based electronics, such as tissue pressure, body motion, temperature, metabolites,
including developing critical tools, materials and processes. electrolyte balance, and disease-related biomarkers. Transdermal
drug delivery devices can also be integrated into electronic skin to
enhance its non-invasive, real-time dynamic therapy functions.[6]
Drug Delivering
The use of nanotechnology in targeted drug delivery systems
(DDS). A targeted DDS can improve the delivery and local
concentration of drugs. The use of nanoparticles (NPs) and
nanostructured materials for delivering drugs to the targeted zone
of action is preferred owing to their optimal size and drug loading
and releasing characteristics[7]. Example of operation in figure
4.
In the final we can combine this with the technology tattoos in
other to delivery drugs if some value changes from what are
being measure. For example, if the sensor notices a dramatic
Figure 3- Schematic that shows the offered baseline process
change can automatically delivery the drug.
BodyNet sensor:
This sensor developed by Scientists from Stanford University,
measures the pulse and rate of respiration through detection of
the expansion and contraction of the skin. Applying in elbows or
knees this sensor can track the movement of the body parts, by
measuring tightening or relaxation of the skin.
Electronic Tattoos:
Created in the Coimbra University the electronic tattoos are
another example of a sensor that can measure muscle activity,
breathing, body temperature, brain activity, even emotions.
Printed in 2D using a composite and transferred with water to the
Figure 9- BodyNet sensor skin.
Some researchers suggest that a “Piezoelectric” printer is preferable The two most significant physical methods are evaporation-
to a “Thermal Bubble” printer to print conductive circuits because it condensation and laser ablation. The benefits of physical methods
is less likely to change the composition and characteristics of the over chemical processes are the absence of solvent contamination in
conductive ink.[20] the generated thin films and the uniformity of nanoparticles
distribution. On the other hand, the physical methods consume a great
In order to change a “Piezoelectric” printer is needed to add the ink
amount of energy while raising the environmental temperature around
cartridges which will extend beyond the printer chassis. Also is
the source material and requires a lot of time to achieve thermal
needed to install air filters on the top of the cartridges because, in this
stability.[22]
way, a vacuum is not formed inside of the container when ink is being
drawn out. The final step is to fill the cartridges with conductive ink. Condensation-evaporation method involves the use of tube furnace. A
In this way, is possible to change a “Piezoelectric” printer to a printer solution mixture of silver nitrate and sodium acetate is heated in tube
of conductive circuits. On the figure 19 shows a example of a furnace, and it converts the liquid into gas. Then there will be the
“Piezoelectric” printer modified which is capable print conductive formation of silver nanoparticles after cooling process. On the figure
circuits.[20] 20 shows this kind of process.[23]
Disadvantages:
• Still need to be more accurate with skin contract
• Because the human epidermis naturally eliminates dead
skin cells, further research is needed to find materials
that can adhere to the skin without sloughing off or
wiping off in the presence of sweat.[12]
• There may be still have some issues between contact
with water and the tattoo.
• After some hours starts to fracture or delaminate, if you
Figure 22 – Chemical method for synthesis of silver nanoparticles.[23]
want to keep for some days you have to apply liquid
bandage coverage.
Notes and references 17 The electronic tattoo that can monitor patient
symptoms remotely [Internet] 2018 [cited 25 June
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https://ironinktattoo.com/history-of-tattoos/ monitor-patient-symptoms
2 Nanotechnology [Internet]. 2020 [cited 17 June 2022]. 18 Biomedical Sensors: Types of sensors and How it works
Available from: [Internet] 2005 [cited 26 June 2022]. Available from:
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tml edical-sensors-types-of-sensors-and-how-it-works/
3 Nanocomposites [Internet]. Nanowerk.com. 2022 [cited 19 Pietro Mandracci, “Chemical Vapor Deposition for
17 June 2022]. Available from: Nanotechnology”, 2018, [cited 26 June 2022]. Available
https://www.nanowerk.com/nanocomposites.php from: https://www.intechopen.com/chapters/63774
4 Virendra S. Graphene based materials: Past, present and 20 Print Conductive Circuits with an Inkjet Printer,
future. 56th ed. Progress in Materials Science. 2011. p. remotely [Internet] 2008 [cited 26 June 2022]. Available
1178-1271. DOI: from: https://www.instructables.com/Print-
https://doi.org/10.1016/j.pmatsci.2011.03.003 Conductive-Circuits-With-An-Inkjet-Printer/
5 2D-EPL offers developers the chance to test graphene- 21 Inkjet-compatible conductive ink lets users make their
based sensors | Graphene Flagship [Internet]. own electronics at home [Internet] 2015 [cited 26 June
Graphene-flagship.eu. 2022 [cited 20 June 2022]. 2022]. Available from:
Available from: https://graphene- https://eandt.theiet.org/content/articles/2019/04/inkj
flagship.eu/graphene/news/2d-epl-offers-developers- et-compatible-conductive-ink-lets-users-make-their-
the-chance-to-test-graphene-based-sensors/ own-electronics-at-home/
6 Ma Z, Li S, Wang H, Cheng W, Li Y, Pan L, et al. Advanced 22 Krishna Rajan, ignazio Roppolo. Annalisa Chiappone,
electronic skin devices for healthcare applications. Vol. Sergio Bocchin, Denis Perrone, Alessandro Chiolerio,
7, Journal of Materials Chemistry B. Royal Society of “Silver nanoparticle ink technology: state of the
Chemistry; 2019. p. 173–97. DOI: 10.1039/c8tb02862a art”,2016
7 Afzal Shah, Saima Aftab, Jan Nisar, Muhammad Naeem 23 Shahzad SHARIF Mughal, Faheem Abbas, and
Ashiq, Faiza Jan Iftikhar, Nanocarriers for targeted drug Muhammad Usman Tahir, “Role of Silver Nanoparticles
delivery, Journal of Drug Delivery Science and in Colorimetric Detection of Biomolecules”, 2019
Technology, Volume 62, 2021, 102426, ISSN 1773-2247, 24 Hongshui Wang, Xueliang Qiao, Jianguo Chen, and
https://doi.org/10.1016/j.jddst.2021.102426. Shiyuan Ding, “Preparation of silver nanoparticles by
8 Nabais, C. P. (2007). Intelligent Technological Tattos. chemical reduction method”, 2005
Science, Art, and Techonoly on and under the Skin, p. 6.
9 What is a Digital Tattoo? Digital Tattoos Explained - The
Medical Futurist [Internet]. The Medical Futurist. 2022
[cited 22 June 2022]. Available from:
https://medicalfuturist.com/wiki/digital-tattoo/
10 Coimbra U. Tatuagens eletrónicas permitem
monitorização da saúde [Internet]. uc.pt. 2022 [cited 22
June 2022]. Available from:
https://noticias.uc.pt/artigos/tatuagens-eletronicas-
permitem-monitorizacao-da-saude/
11 Kabiri Ameri S, Ho R, Jang H, Tao L, Wang Y, Wang L, et
al. Graphene Electronic Tattoo Sensors. ACS Nano. 2017
Aug 22;11(8):7634–41.
12 Micro-tech: Tattoos to Monitor Your Heart, Dissolving
Electronics & Porta [Internet]. Healthline. 2022 [cited 22
June 2022]. Available from:
https://www.healthline.com/health-news/tech-micro-
electronics-can-monitor-your-vital-signs-
040113#Electronic-Tattoos
13 Art S. Electronic Skin Sensors – Scitech Patent Art
[Internet]. Patent-art.com. 2022 [cited 23 June 2022].
Available from: https://www.patent-
art.com/knowledge-center/electronic-skin-sensors/
14 Laurie Donaldson, “Smart tattoo: Electronic materials”,
2011 [cited 25 June 2022] Available from:
https://www.sciencedirect.com/science/article/pii/S13
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15 Topics of nanotechnology [Internet], 2019 [cited 24 June
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https://www.nanowerk.com/nanotechnology/ten_thin
gs_you_should_know_3.php
16 What is special about the nanoscale [Internet], 2018
[cited 24 June 2022]. Available from:
https://www.nano.gov/nanotech-101/special