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Blood Chemistry

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Blood Chemistry

Plasma components – these are the materials dissolved or suspended in the plasma. Mixture of these
components:

 Water
 Proteins – most abundant substance in the plasma. Contains 3 major types
o Albumin
o globulins
o fibrinogen
 Ions
 Nitrogenous compounds
o Blood Urea Nitrogen (BUN) – a nitrogenous waste compound
 Nutrients
o Glucose
o Fats
o Amino acids
o Minerals
o vitamins
 Salts
 Enzymes
 Hormones
 Wastes
 Dissolved gases
o Dissolved oxygen
o Dissolved carbon dioxide

Why a blood chemistry test is done?

 To evaluate a person’s general health status


 To evaluate organ function
 To evaluate body’s electrolyte balance
 To identify organ damage or injury
 Identify damage tissues that secrete chemicals into the blood

Substances are being circulated through the blood, that is what our circulatory system does. These
substance are being produced by an organ, nutrient to an organ, as well as the wastes of the organs, for
our body to work properly.

Blood chemistry gives a glimpse of the health of the body, the body systems. It will help us to tell what is
the condition, what might be wrong in certain organ of the body.
Blood Chemistry

A certain substance of the blood, there is a certain value or range that is considered normal, or ideal…. It
the amount of a certain substance is too much, or too low, it might be a sign that something is wrong or
in the body.

Some important blood chemistry tests:

Test Clinical Significance


Bilirubin High Level
 a substance produced during the normal  liver damage or disease
breakdown of red blood cells. Bilirubin passes  anemia
through the liver and is excreted in stool.
Blood Urea Nitrogen (BUN) High Level
 a waste product of kidney filtered out of the  improper working of kidneys
body.  dehydration
 excessive bleeding
 severe infection that may lead to shock
Creatinine High Level
 a waste product of kidney filtered out of the  improper working of kidneys
body.  urinary obstruction
 dehydration
 muscle damage
Glucose High Level
 a type of sugar that the body uses for energy  pancreas is not producing enough insulin
 inflammation of pancreas
 diabetes
 liver damage or disease
Triglycerides High Level
 A type of fat in the blood  Can increase the risk of damage to the
pancreas
Cholesterol High Level
 a fatty substance that circulates in the blood  risk of cardiovascular disease (heart attack
or stroke)
Albumin (Protein) High Level
 mainly in the liver. It helps keep the blood from  dehydration
leaking out of blood vessels  cancer

Low Level
 liver damage or disease
 kidney damage or disorder
 poor nutrition
 excessive bleeding
Globulin (Protein) High Level
 present in the liver and immune system.
Blood Chemistry

 Certain globulins bind with hemoglobin while  dehydration


others transport metals such as iron in the  cancer
blood, help fight infection, and blood clot Low Level
 liver damage or disease
 kidney damage or disease
 poor nutrition
 excessive bleeding
Calcium High Level
 an important mineral in the body to build and fix  overactive parathyroid glands
bones, help nerves and muscles work, help (hyperparathyroidism)
blood clot, and help the heart to work  cancer
 bone disorder

Low Level
 Underactive parathyroid glands
(hypoparathyroidism)
 liver damage or disease
 kidney damage or disease
 malnutrition
 pancreatitis

Sources:

https://www.slideshare.net/aroojattique/blood-chemistry-88508352

https://www.news-medical.net/health/Blood-Plasma-Components-and-Function.aspx

http://red-is-blood.blogspot.com/2011/04/blood-chemistry-tests.html

https://blog.vetprep.com/infographic-blood-chemistry-quick-reference

How often tests must be?

What specific tests must be performed?

Depends to the doctor based on the condition of the patient,

Need to consider tay cost.. different substance to test requires different process/equipment

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