Nothing Special   »   [go: up one dir, main page]
Scribd Logo
Upload

Welcome to Scribd!

  • 9 views

    Twin Study

    Uploaded by

    madison Deli
    Epidemiology studies the distribution and determinants of disease frequency in human populations. Genetic epidemiology examines the role of genetics and environment in disease causation, and has made important contributions to medicine through approaches like newborn screening for inherited disorders. Twin studies and analyses of familial aggregation, segregation, and linkage are key designs used to study both monogenic and complex genetic disorders.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd

    Twin Study

    Uploaded by

    madison Deli
    9 views1 page
    Epidemiology studies the distribution and determinants of disease frequency in human populations. Genetic epidemiology examines the role of genetics and environment in disease causation, and has made important contributions to medicine through approaches like newborn screening for inherited disorders. Twin studies and analyses of familial aggregation, segregation, and linkage are key designs used to study both monogenic and complex genetic disorders.

    Original Description:

    Original Title

    TWIN-STUDY

    Copyright

    © © All Rights Reserved

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Epidemiology studies the distribution and determinants of disease frequency in human populations. Genetic epidemiology examines the role of genetics and environment in disease causation, and has made important contributions to medicine through approaches like newborn screening for inherited disorders. Twin studies and analyses of familial aggregation, segregation, and linkage are key designs used to study both monogenic and complex genetic disorders.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    9 views1 page

    Twin Study

    Uploaded by

    madison Deli
    Epidemiology studies the distribution and determinants of disease frequency in human populations. Genetic epidemiology examines the role of genetics and environment in disease causation, and has made important contributions to medicine through approaches like newborn screening for inherited disorders. Twin studies and analyses of familial aggregation, segregation, and linkage are key designs used to study both monogenic and complex genetic disorders.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 1

    .

    GROUP ACTIVITY
    1. Epidemiology is the study of distribution and determinants of disease frequency
    in human populations and the use of this information to control and promote
    health.

    2. One of the simplest designs in heritability study is the “twin study.” This study
    design uses the variance component framework and its frequency to estimate
    heritability.

    3. Different forms of inheritance that can help to determine whether it is an


    autosomal dominant or recessive.

    4. Genetic epidemiology has made important contributions to medicine and public


    health. One example is the use of Newborn screening to detect inherited
    disorders in offspring.

    5. Genetic epidemiology have been based on familial aggregation, segregation or


    linkage analysis, mainly allowing the study of monogenic disorders.

    6. There is relative size of genetic effect in relation to other sources of variation in


    disease risk (environmental effects such as intrauterine environment, physical
    and chemical effects as well as behavioral and social aspects).

    7. The genetic epidemiology can also be skewed by the presence of evolutionary


    pressures that induce negative selection during molecular evolution. This
    negative selection can be determined by tracking the skewness of the distribution
    of mutations with putatively severe effects as compared to the distribution of
    mutations with putatively mild or absent effect.

    8. Inheritance of role of genetics and environment in disease causation by knowing


    its mechanism of interaction.

    9. Natal environment can categorized into prenatal environment and post natal
    environment.

    10. For evaluating screening tools include validity, variability, yield, sensitivity,
    specificity,predictive value and screening test.

    You might also like