Parasitic Infections
Parasitic Infections
Parasitic Infections
COMMUNITY
SOCIETAL RESPONSIBILITY
EXCELLENCE
PARASITIC INFECTIONS
African American
Leishmaniasis Toxoplasmosis
Trypanosomiasis Trypanosomiasis
Early stages
• infects the blood
• bite causes a painful lesion or chancre
Late stages
• infects the CSF
• causes lethargy
• eyelids droop, the individual falls asleep while eating or even standing
• further causes coma, and death is usually inevitable
AFRICAN TRYPANOSOMIASIS
AFRICAN TRYPANOSOMIASIS
AFRICAN TRYPANOSOMIASIS
AFRICAN TRYPANOSOMIASIS
AFRICAN TRYPANOSOMIASIS
AFRICAN TRYPANOSOMIASIS
AMERICAN TRYPANOSOMIASIS
Chaga’s disease
Contact of
EA : Trypanosoma cruzi Reduviid bug
feces to
conjunctiva or
breaks of skin
Bite from a
Reduviid bug
Mode of
Transmission
• Assassin bug
• Kissing bug
AMERICAN TRYPANOSOMIASIS
EA : Leishmania sp.
Leishmania are flagellated protozoa
RES :
Bite of a
Humans Female Sand
Fly
Dogs containing
Promastigote
Mode of
Transmission
LEISHMANIASIS
PROMASTIGOTE
• extracellular form
• motile
• found at the saliva of the sand fly
AMASTIGOTE
• intracellular form
• non motile
• invades and proliferates inside host’s macrophages
LEISHMANIASIS
LEISHMANIASIS
LEISHMANIASIS
LEISHMANIASIS
LEISHMANIASIS
LEISHMANIASIS
LEISHMANIASIS
LEISHMANIASIS
LEISHMANIASIS
LEISHMANIASIS
TOXOPLASMOSIS
EA : Toxoplasma gondii
HOST: Blood
Humans trans-
fusion
Cats (definitive host) Fecal-
oral
Mode of
Transmission
• Accidental ingestion
of cat feces infected
with oocyst during:
• gardening Trans-
• cleaning cat’s placental
litter box
• Eating raw or
undercooked meat
contaminated with
cat feces
TOXOPLASMOSIS
Immunocompetent
• no/mild symptoms
Preventive measures:
• Wear gloves when you garden or do anything outdoors that
involves handling soil.
• Wash your hands well with soap and water:
• after outdoor activities
• before you eat or prepare any food
• after handling raw meat
• Avoid eating uncooked eggs and unpasteurized milk
TOXOPLASMOSIS
Preventive measures:
• When preparing raw meat, wash any cutting boards, sinks,
knives, and other utensils that might have touched the
raw meat thoroughly
• Wash fruits and vegetables thoroughly
• Cook all meat thoroughly
• Avoid exposure to cats if pregnant
TOXOPLASMOSIS
TOXOPLASMOSIS
TOXOPLASMOSIS
PRIMARY AMOEBIC MENINGOENCEPHALITIS
(PAM)
NAEGLERIA
MENINGOENCEPHALITIS
Contact to
EA : Naegleria fowleri nasal mucosa
from
Initially invades the nasal mucosa contaminate
d ponds and
then travels to the brain lakes Mode of
Fatality rate is nearly 100% Transmission
PRIMARY AMOEBIC MENINGOENCEPHALITIS
(PAM)
ACANTHAMOEBA KERATITIS
AMOEBIC CONJUNCTIVITIS
EA : Acanthamoeba sp.
Contact of
conjunctiva
with infected Mode of
water thru: Transmission
• Contact lenses
• using home-made
non-sterile
cleaning solutions
• Spas and hot tubs
ACANTHAMOEBA KERATITIS
causes mild inflammation at first then leads to severe eye damage and pain
due to extensive conjunctival damage
Fecal-oral
route /
Ingestion of
contaminated
water Mode of
Transmission