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Acute Kidney Injury Poster

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Acute Kidney Injury – Initial Management And Referral

Renal Function should be checked on all Emergency Admissions (then every 24 hours if AKI)

Urinalysis for all Staging AKI (Creatinine and Urine Output criteria) Accurate fluid
balance/observations

Blood Proteinuria Leucocytes


If high early warning score
request critical care
Vasculitic ACR MSU
screen:
outreach review.
If hypotensive despite
ANCA
ANA adequate fluid resuscitation
C3, C4, or systolic BP < 90mmHg
Cryoglob after > 2 L fluid then senior
Myeloma +/- outreach review.
screen: Caution required for heart
Igs
SFL
failure patients: use clinical
judgement for degree of
volume replacement.
Renal referral for Acute Kidney Injury
AKI Stage 1 Refer only if cause uncertain, suspected vasculitic or complications of AKI (high potassium etc)
AKI Stage 2 All except for those where the diagnosis & plan are clear with evidence of rapid improvement
AKI Stage 3 All patients should be referred & discussed with renal team unless palliative

Management for all stages of AKI = “STOP” AKI


S SEPSIS / HYPOTENSION / PRERENAL / ATN. Antibiotics within 1 hour (renal dosing). Avoid empirical gentamycin in AKI. Relevant cultures (urine/blood) before antibiotics. Adequate fluid resuscitation.
T TOXINS – All patients should have a nephrotoxic medication review (e.g. NSAID/ACEi/ARB) avoid post-operative NSAID
O OBSTRUCTION - AKI is usually fully reversed if obstruction relieved promptly. USS scan within 24 hours
P PARENCHYMAL / INTRINSIC RENAL DISEASE, think rapidly progressive gn such as vasculitis in someone with rash & active urine sediment. Rhabdomyolysis if clinically suspected (CK).
If anaemic/low platelet count consider HUS/TTP. Tubulointerstitial nephritis if new drug commenced recently & no obvious alternative cause.

For detailed guidelines refer to the Black Country Network AKI guidelines which is available on the Pathology Website
(http://www.royalwolverhampton.nhs.uk/EasySiteWeb/GatewayLink.aspx?alId=5252 ) and the Renal intranet pages.

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