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Drug Study: Phinma University of Pangasinan

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PHINMA UNIVERSITY OF PANGASINAN

COLLEGE OF HEALTH SCIENCES


Nursing Department

DRUG STUDY
NURSING
DRUG INDICATION ACTION DRUG INTERACTION CONTRAINDICATION ADVERSE EFFECT
CONSIDERATION
Generic >serious infections >inhibits protein >Acyclovir, amphotericin B, >contraindicated in >CNS: fever, headache, >obtain specimen for culture
cephalosporins, cidofovir, and sensitivity test before
Name: caused by sensitive synthesis by patients hypertensive to lethargy, encephalopathy,
cisplatin, metathroxtflurane, drug or other confusion, dizziness, giving first dose. Therapy may
gentamycin strains of binding directly to vancomycin, other begin while awaiting results.
pseudomonas the 30s ribosomal aminoglycosides. seizures, numbness,
aminoglycosides: may increase >evaluate patient’s hearing
>use cautiously in peripheral neuropathy,
aeruginosa, subunit; ototoxicity and nephrotoxicity. before and during therapy.
Monitor hearing and renal
neonates, infants, elderly vertigo, ataxia, tingling. Notify prescriber if patient
Escherichia coli, bactericidal.
function test results. patients, and patients with >CV: hypotension complains of tinnitus, vertigo,
Brand Name: Proteus, Klebsiella or impaired renal function or >EENT: ototoxicity, blurred
>Dimenhydrinate: may mask or hearing loss
Garamycin Staphylococcus. neuromuscular disorders. vision, and tinnitus. >weigh patient and review
ototoxicity symptoms. Monitor
>to prevent >GI: vomiting, nausea renal function studies before
hearing.
endocarditis before >General anesthetics: may >GU: nephrotoxicity, therapy begins.
Drug GI or GU procedure increase neuromuscular possible increase in urinary >Alert: use preservative-free
form when intrathecal route is
Classification: or surgery. blockade. Monitor patient excretion of casts.
>Hematologic: anemia, indicated.
Pregnancy risk closely. >monitor renal function: urine
category D >Indomethacin: may increase eosinophilia, leukopenia,
output, specific gravity,
peak and trough levels of thrombocytopenia, urinalysis, BUN and creatinine
gentamycin. Monitor agranulocytosis levels, and creatinine clearance.
gentamycin level. >Musculoskeletal: muscle Report to prescriber evidence
>IV loop diuretics (furosemide): twitching, myasthenia of declining renal function.
may increase risk of gravis-like syndrome >Hemodialysis for 8hrs may
ototoxicity. Monitor patient’s >Respiratory: apnea remove up to 50% of drug from
>Skin: rash, urticarial, blood.
hearing.
pruritus, injection site pain > watch for signs and
>Parenteral penicillins symptoms of super infections
(ampicillin and tiracillin): may >other: anaphylaxis
(esp. for upper resp. tract) such
inactivate gentamycin into as continued fever, chills, abd
vitro. Don’t mix together. increased pulse rate.

SUBMITTED BY: Giselle Chloe B. Ico

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