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Calculate The Max Doses of Local Anesthesia in Dentistry

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The max dose of L.A in dentistry


? How to calculate the max dose of L.A in dentistry
Local Anesthetics

Local anesthetics are the most commonly


used drugs in dentistry. This article provides a
brief update on the pharmacology, adverse
effects and clinical applications of these drugs,
. as well as the role of vasoconstrictors

Local Anesthesia in adult Dentistry

Local Anesthesia in Pediatric Dentistry

/ http://www.dentalcare.com Steven Schwartz, DDS C LINICAL P RACTICE Book An Update on Local Anesthetics in Dentistry • Daniel A. Haas, BSc, DDS, BScD, PhD, FRCD(C)
Local anesthetics

?!!Why we have to know the max dose of L.A

Because

With overdose there may be health problems may occur to the patient
Toxicity
The toxicity of local anesthetics is a function of systemic absorption. High blood levels of the
drug may be due to repeated injections or could result from a single inadvertant intravascular
. administration
Adverse reactions of commonly used local
anesthetics
Psychogenic
Syncope (most common) Hyperventilation Nausea, vomiting Alterations in heart rate or blood pressure Mimicking
of an allergic reaction

Allergic (potential allergens)


Esters (true amide allergy is very rare) Metabisulfite (present with epinephrine and with levonordefrin)
Methylparaben (no longer added to dental cartridges)

Toxic effects
Primarily neurologic signs May initially manifest as sedation, lightheadedness, slurred speech, mood alteration,
diplopia, sensory disturbances, disorientation, muscle twitching Higher blood levels may result in tremors,
respiratory depression, tonic–clonic seizures If severe, may result
in coma, respiratory arrest, cardiovascular collapse

Methemoglobinemia
Associated with prilocaine, articaine, benzocaine

Paresthesia
Apparently more common with articaine and prilocaine

C LINICAL P RACTICE Book An Update on Local Anesthetics in Dentistry • Daniel A. Haas, BSc, DDS, BScD, PhD, FRCD(C)
the max dose of L.A
Recommended maximum doses of local
anesthetics with vasoconstrictor

No Maximum Maximum Drug


of cartridges dose

7 mg/kg (up to 500 mg) 7 Articaine


mg/kg in children 5

10 mg/kg (up to 200 mg) 2 Bupivacaine

13 mg/kg (up to 500 mg) 7 Lidocaine

11 mg/kg (up to 400 mg) 6.6 Mepivacaine


) or 7 if plaina (

8 mg/kg (up to 500 mg) 8 Prilocaine

a3% solution without vasoconstrictor C LINICAL P RACTICE Book An Update on Local Anesthetics in Dentistry • Daniel A. Haas, BSc, DDS, BScD, PhD, FRCD(C)
Maximum Recommended Dosage of Local Anesthetic Agents (AAPD). 1
the max dose of L.A American Academy of Pediatric Dentistry

Maximum Dosage

Maximum Total
Anesthetic mg/1.7ml carpule
Dosage

mg/kg mg/lb

Lidocaine 2% 1:000,000 epi 4.4 2.0 300mg 34mg

Mepivacaine 3% plain 4.4 2.0 300mg 51mg

Articaine 4% 1:100,000 epi 7.0 3.2 500mg 68mg

Prilocaine 4% plain 8.0 3.6 600mg 68mg

Bupivacaine 0.5% 1:200,000 epi 1.3 0.6 90mg 8.5mg

/ http://www.dentalcare.com Steven Schwartz, DDS


the max dose of L.A Maximum Recommended Dosage of
Local Anesthetic Agents (MRD). 3
Membership in Restorative Dentistry
(MRD)

Maximum Dosage

Maximum Total
Anesthetic mg/1.7ml cartridge
Dosage

mg/kg mg/lb

Lidocaine 2% 1:000,000 epi 7.0 3.2 500mg 34mg

Mepivacaine 3% plain 6.6 3.0 400mg 51mg

Articaine 4% 1:100,000 epi 7.0 3.2 None Listed 68mg

Prilocaine 4% plain 6.0 2.7 400mg 68mg

Bupivacaine 0.5% 1:200,000 epi 2.0 0.9 90mg 8.5mg

/ http://www.dentalcare.com Steven Schwartz, DDS


calculate the max dose of L.A in dentistry
calculate the max dose of L.A in dentistry
To calculate the maximum amount of
lidocaine 2% with 1:100,000 epinephrine and
the number of cartridges that can be safely
administered to a 30 pound patient, the
clinician would perform the following
. calculations

Maximum Dosage (mg/lbs) X weight (lbs) = Maximum Total Dosage (mg)


X 30 = 60 mgs 2.0

Maximum Total Dosage (mg) ÷ mg/cartidge = Maximum # cartridges


cartridges 1.67 = 36 ÷ 60

Thus for a 30 pound child one can safely


administer 1.67 cartridges of lidocaine 2%
. with 1:100,000 epinephrine

Note : maximum dosage (mg/lbs) = 2.0mg/lbs


maximum dosage (mg/kg) = 4.4mg/kg Note : 1 carpule holds 1.8 ml of solution = 36mg
1kg = 2.2 lbs
/ http://www.dentalcare.com Steven Schwartz, DDS
calculate the max dose of L.A in dentistry
To calculate the maximum amount of
mepivacaine 3% plain and the number of
cartridges that can be administered to a 30
pound patient the clinician would perform the
. following calculations

Maximum Dosage (mg/lbs) X weight (lbs) = Maximum Total Dosage (mg)


X 30 = 60 mgs 2.0

Maximum Total Dosage (mg) ÷ mg/cartidge = Maximum # cartridges


cartridge 1.1 = 54 ÷ 60

Note the difference between the number of


cartridges of lidocaine 2% and mepivacaine
3% that can be administered to a 30 pound
child is due to the difference in the number of
mg of anesthetic solution in a 1.8cc cartridge
of anesthesia; lidocaine contains 36 mg and
. mepivacaine contains 54 mg
Note : maximum dosage (mg/lbs) = 2.0mg/lbs
maximum dosage (mg/kg) = 4.4mg/kg

1kg = 2.2 lbs


/ http://www.dentalcare.com Steven Schwartz, DDS
Quick Dosage Chart for AAPD Maximum
Recommended Dosages

Maximum Number of 1.8ml Cartridges


Age Kg Lbs Lidocaine 2% Mepivicaine 3% Articaine 4%
yrs + 1 7.5 16.5 0.9 0.6 0.7
10.0 22.0 1.2 0.8 1.0
yrs 2-3
12.5 27.5 1.5 1.0 1.2
15.0 33.0 1.8 1.2 1.5
yrs 4-5
17.5 38.5 2.1 1.4 1.7
20.0 44.0 2.4 1.6 2.0
yrs 6-8
22.5 49.5 2.8 1.8 2.2
25.0 55.0 3.1 2.0 2.4
yrs 9-10
30.0 66.0 3.7 2.4 2.9
32.5 71.5 4.0 2.6 3.2
35.0 77.0 4.3 2.9 3.4
yrs + 11
37.5 82.5 4.6 3.1 3.7
40.0 88.0 4.9 3.3 3.9
The maximum amount of local anesthetic agent needs to be reduced if the patient is receiving a supplementary dose of enteral or parenteral
sedative agent for behavior management. The action of the sedative has an additive depressive effect on the central nervous and
cardiovascular systems can initiate overdose consequences
/ http://www.dentalcare.com Steven Schwartz, DDS
Thank you

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