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CASE REPORT

Loss of functional vision even

14April 2019
Patient Details:
73yrs, Female, South Asian

11/04/2019

Presenting Symptoms:
Referred to tertiary eye care hospital by ophthalmologist for OCT.

Difficulty in climbing stairs

Difficulty in recognizing faces

Trouble in distant vision

Reading is ok with near add

Sensitivity to light

Corona or shade around light, moving spots

Dropping of both eye lid since last 6 months

Maintain a chin up posture

Mild discharge & redness

General Health:
History of contact skin allergy one month ago: 3 injections in a week, hydrocortisol cream with
cold compression.

HTN-nil, DM- nil no other systemic disease

Ocular History:
LF cataract extraction with foldable IOl implant

Family Ocular History:


Positive
ADL:
Senior citizen no specific job to do except reading Holy Book for 3hrs in a day along with
activities of daily life.

Clinical Signs:
Vision – OD (sc) 2/60 OS (sc) 1/60

Near vision – Old rx: +3.0 DS BE

Refraction - OD: +2.00/-2.00@100 , 6/36 OS: +2.50/-2.00@60, 1/60

Pin Hole - OD: 6/60- OS: 1/60 with ETDRS Chart.

Near Vision - OU sc: N12 with +4.00 N8.

AHP: Chin up

PD: 58mm

VD: 12.00

Avg.Curvature – OD: 45.25 D OS: 45.50D

RT LF

full Eom full

Pterygium+ Conjuctiva Pterygium+


Senile ptosis ++, discharge lids Senile ptosis++, discharge
NAD NAD
Cornea
NAD Sclera NAD

RRR, No RAPRD Pupil RRR, No RAPD

NS+++, cortical ++ Lens Pseudophacia, PCO

NAD Iris NAD

NAD AC NAD

Tesselated flat Macula Macular scar


0.2 CD ( +60D) 0.2

12mmHg IOP(GAT) 11mmHg

Image of Rt. Mature Cataract

Differential Diagnosis:
Myogenic Ptosis- Malfunction of the levator muscle restricts the eyelid from being elevated into
right position. The frequent cause is myasthenia gravis, congenital myopathies, myotonic
dystrophy, and chronic progressive external ophthalmoplegia. It`s a progressive condition
which may recurrent. Variable ptosis is a key feature of Myasthenia Gravis. Ocular motility
imbalance is also an association in it that in this case is normal. The other symptoms and signs
of Myasthenia are absent (Finsterer, 2003), ( Wong , Beckingsale ,Oley and Sullivan, 2002),

(Kasnki, 2016).
Neurogenic ptosis: Ptosis may be caused due to the malfunction or disruptionof the central
nervous system or to the oculomotor orsympathetic nerve(s) .As the levator has the key role in
keeping the lid open, profound deficits of third nerve function usually results in severe or
complete ptosis.There are no signs of Third nerve here except ptosis. Diabetes, Multiple
Sclerosis also cause ptosis but the patient has no systemic disease history (Finsterer, 2003)

Mechanical ptosis: Orbital fat prolapse, eyelid tumour may cause lid to be too heavy for the
muscle to elevate it.There`s no presence of mass (Finsterer, 2003).Choroidal Revascularization
(CNV): Sudden deterioration of vision within few days especially central vision including color
confusion and metamorphosis (condition in which straight lines presume as wavy) Disruption of
new blood vessels accelerate the symptoms. (“Choroidal neovascularization”, 2019).

Cystoid Macular Edema: Retinal edema causes decrease in visual acuity along with low contrast
sensitivity and distorted lines that cause trouble in face recognition and fine vision. Patient
observes spot due to Scotia formation.( Nussenblatt ,Kaufman , Palestine & Davis
,Ferris,1987).

Retinal Detachment: It`s more common in people above the age 50.It’s a painless condition. But almost
every time the alarming signs pop-up before it occur or has advanced, as in the sudden onset of
floaters, little specks which seem to loft through field of view, Flashes of light (photopsia), Hazy view,
Progressive loss of side (peripheral) view, A curtain-like shade over field of view.

(Kasnki, 2016).

Most likely Diagnosis:

ARMD: OU

VMT: RT

Neuclear Sclerosis – MATURE: RT

Aponeurotic Ptosis: OU

Investigation:
Due to the presence scar in the left eye and flattening of macula observed through the slit lamp
it was decided to go for the OCT scan of bilateral macula to get the clear picture of fundus
pathology.It stated that view of both eyes were hazy with viterous macular traction in the right
eye. Thickness of right macula was 179um and 365um of the left. Whereas, the inner retinal
layer and retinal pigment epithelium seemed to be normal. There was an evident scaring of the
foveal region in the both eyes with no edema and hemorrhage. Macula came out to be flat in
the left eye ruling out ARMD in both eyes. Biomicroscopy & Central 10-degree computerized
automated perimetry would be done in the next visit. (“Care of patient”).

Management Of The Case In Optometry Practice (based on most likely


diagnosis)
Eye drops Alzox and vision1 were suggested to be instilled in both eyes four times a day for a
month to resolve the discharge. For functional vision UVR protective (“Care of patient”) distant
and near vision glasses were also recommended till the time patient decide to go for cataract
extraction and IOL implantation(phaco+foldable IOL) in the right eye. Referral was made to the
Oculoplasty department for opinion regarding ptosis as it was almost covering the visual axis of
both eyes due to which patient maintained a chin up posture. Most probably bilateral.(
Finsterer.J 2003).As there is no cure, but treatment could slow down the disease progression
so to save patient from having profound visual loss. Ultimately the patient would be referred for
low vision rehabilitation even if after phaco surgery the vision would not be equal or more the
6/12 OU for which chances are very less due to scar formation and damage done already. Green
leafy, other green, yellow vegetables and egg yolk were advised as that`s an enriched source of
vitamin A, Zeaxanthin and Lutein.(“Care of patient”),(“Lutein and zeaxanthin,”
2016),(Kasnki,2016).Food containing Omega-3,Vitamin C,E,zinc,and copper was recommended
her to take in regular basis along with a prescription of case appropriate multivitamin dose.(“Age-
Related Macular Degeneration”,2005),( “Care of patient”), ( Kasnki,2016).A study conducted by
the National Eye Institute of the National Institutes of Health, namely AREDS (Age-Related Eye
Disease Study), had proved benefits of supplement formula that has vitamins C and E, beta-
carotene, zinc, and copper. The research stated, the risk of vision deterioration goes down for
some patients with moderate to severe dry AMD. An updated AREDS2 formula recently
included lutein, zeaxanthin, and omega-3 fatty acids and abolished beta-carotene, which might not
be safe for smokers. As Beta-carotene found to cause higher risk of lung cancer in smokers. Anti-
angiogenic drugs, Photodynamic laser therapy, Submacular surgery could be a treatment option
that would be decided by the vitre-retinal surgeon later in the follow-ups if suitable for the
case.(Kasnki, 2016),(“Care of patient”).Patient education was done giving information regarding
the disease and prognosis.reviewed the symptoms also encouraged her for compliance with the
treatment regime. Advised to promptly visit hospital if new symptoms appear i.e, blurred vision
Scotia, dysmorphopsia) (“care of patient”), (Kasnki, 2016).Follow-up after one month had been
scheduled.
REFRENCES
1. Finsterer.J 2003,` Ptosis: Causes, Presentation, and Management` Aesthetic Plastic
Surgery` , [online],Vol.27,viewed 12 April 2019 .
< https://link.springer.com/article/10.1007%2Fs00266-003-0127-5#citeas>.
2. Wong V-A, Beckingsale P-S,Oley C-A, Sullivan T-M 2002,` Management of myogenic
ptosis`American Academy of ophthalmology, [online],Vol. 109, viewed 12 Aril
2019<https://www.aaojournal.org/article/S0161-6420(02)01009-6/fulltext>.
3. `Choroidal neovascularization` 2019, [online], Wikipedia Available
at https://en.wikipedia.org/wiki/Choroidal_neovascularization (Accessed:12 April 2019)
4. Care of patient with age related macular degeneration, ‘American optometric
association ` [online] viewed at 12 April
2019,<https://www.aoa.org/documents/optometrists/QRG-6.pdf> .
5. Nussenblatt R-B,Kaufman S-C, Palestine A-G, Davis M-D,Ferris F-L 1987,` Macular
Thickening and Visual Acuity` American Academy of Ophthamology,vol.94,viewed 12
April 2019 < http://libraryguides.vu.edu.au/harvard/journal-articles>.
6. Lutein and zeaxanthin: Eye and vision benefits 2016, [online], All about vision, viewed
12 April 2019, <https://www.allaboutvision.com/nutrition/lutein.htm>.
7. Age-Related Macular Degeneration Treatment 2005, [online],WebMD,accessed on 12
April 2019,<https://www.webmd.com/eye-health/macular-degeneration/age-related-
macular-degeneration-treatment#1>.
8. Mayo Clinic 2019, [online],Retinal Detachment, accessed 12 April 2019,<
https://www.mayoclinic.org/diseases-conditions/retinal-detachment/symptoms-
causes/syc-20351344>.
9. Kasnki,J.(2016),Clinical Ophthalmology,8th Edition, Elsevier,598-616.
10. Kasnki,J.(2016),Clinical Ophthalmology,8th Edition, Elsevier, 838.
Abbreviations:
ARMD__Age Related Macular Degeneration

VMT___ Viterous Macular Traction

OU: Both eyes, RT : Right eye , LF : Left eye,

Vit.A : Vitamin A

PD: Pupillary Distance

VD: Vertex Distance

AHP: Abnormal Head Posture

SC: Without Glasses

NAD: No Abormality Detected

RRR : Right Round Reactive

RAPD: Relative Afferent Pupillary Defect

Phaco: Phacoemulsification

PCO : Posterior Capsular Opacity

NS: Nuclear Sclerosis

EOM: Extra Ocular Muscles

AC: Anterior Chamber

IOP: Intra Ocular Pressure

CD: Cup to Disc

GAT: Goldmann Applanataion Tonometer

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