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or immediate action has represented only a well-established natural science rules the modern
temporary palliative to the problems of hidden science. In 1992, 86% out of a total of 627 papers
consequences brought about by the reflexivity of presented in the New Research sessions at the
consciousness. The destruction of traditional annual meeting of the American Psychiatric
values, scientific ambiguities, social insecurity all Association were biomedically oriented and
lead to the formation of a nihilistic philosophy more than 88% from 227 papers presented by
of life. Plain and cynical, the negative nihilistic “young investigators” were biomedically
answer to the fundamental question of any focused.5 Twenty years later there is no sign of
sentient being whether there is a meaning of life change. In the list of Top Ten Research Advances
outlines the cognitive infrastructure of any of 2012 proposed by the Director of National
depression. “That’s the thing about depression: institute for Mental Health, eight were biomedical
A human being can survive almost anything, as topics. However, these breakthroughs are “not
long as she sees the end in sight. But depression directly focused on mental disorders, but they
is so insidious, and it compounds daily, that it’s suggested new vistas for biology that will almost
impossible to ever see the end.”2 And this certainly change the way we understand serious
constitutes the exceptionality of the depressive mental illness and neurodevelopmental
phenomenon. More than the dreadful but disorders.”6 These “advances” include topics as
vitalizing anxiety in the face of the salience of “epigenomics”, “neurodevelopmental
death, depression brings about hopelessness and genomics”, “optogenetics and oscillations in the
depletes every innate living thrill. brain,” “mapping the human brain at the
The contradiction between the rational molecular level” and “mapping the human
cognition of “It is futile” and the biological connectome”, “unexpected genome variation”,
volition of “I want to live” falls in the passive “the human microbiome” and “the ENCyclopedia
state of (organic) depression. Living “into of DNA Elements (ENCODE) project”. Among
immediacy and for preservation” does not lead these top priority advances there is no concern
to depression3, as the being for the moment lacks for any concrete improvement in the assessment,
a proper sense and thereof the need to feel it. prevention or treatment of mental disorder. No
Self-consciousness instead is free in its essence intent for studying the context, the nonclinical
and is found itself in thought and action. Because elements, the alternative therapies or mental
the thought cannot be fulfilled in its completeness health enhancement. The solely humanist
in the act, it will always be left with some advance of modern science of psychiatry seems
uncertainty. And “uncertainty leaves alternatives to be the individualization of the disease for the
to any conclusion open and thus engenders patient, but even this is not a fair progress, quite
freedom of choice - responsibility in not knowing. the opposite.
It is here where confusion, awareness of guilt, Hippocrates has considered “there are three
anxiety and depression are ontologically factors in the practice of medicine: the disease,
grounded.” 4 This metaphysical constituent the patient, and the physician. The physician is
conjugated with the tri-unitary ontological the servant of the science, and the patient must
structure of the human being explains the do what he can to fight the disease with the
difficulties of understanding the depressive assistance of the physician. The physician is the
syndrome mechanisms only through current servant of his art, and the patient must cooperate
scientific paradigm. These profound roots and with the doctor in combating the disease.”7
mixed bio-psycho-social facets makes the Hippocrates established the Art of Medicine “on
depression question less solvable in any linear a solid and unshakeable basis” namely the
logical enquiry. principle “that our natures are the physicians of
The human sciences seem inevitably diseases” and the method of “the exact description
contaminated with this mono-epistemic of nature”.8 More than five hundred years later,
perspective from the more mature natural Galen considered there was only one disease as
sciences. Psychology, the medicine of the soul, is abnormal countless variations of the four
no exception. The paradigm of more humours. He posits the methodological difference
between considering the patient in all of his/her metaphysical truth “that anxiety and depression
particularity and understanding the patient as are ontologically necessary factors of human
an individual instance of a general rule of consciousness. They are ways of experiencing
biomedical science.9 By the particular way he oneself in reality which are indispensable for the
managed this difference, he seems to have development of individual human consciousness
individualized and hence apparently humanized in truth to reality.”13
medicine. „Psychiatry today is Galenic, not Unfortunately, the compulsory need for
Hippocratic. The four humours have become a certitude, which fostered and carried the scientific
half dozen neurotransmitters, whose rise and fall endeavor from its dawn, has a cost. The insurance
we speculatively manipulate with drugs. Careful against uncertainty has as unavoidable
clinical observation and nosology of disease, the complement: the limited mode of enquiry, e.g.
hallmark of Hippocratic thinking, have been the Real could be seen from a single perspective.
replaced by penny-in-the-slot drug-for-symptom For this reason, throughout the entire history of
practice. This pseudoscience is justified on psychology, we witness to a continual alternating
humanistic grounds as being individualized to dominance of two perspectives on the human
the patient. We forget that such extremist being: the behavioral view from outside and the
individualization, which is the opposite of cognitive view from inside. The prolonged
science, produced 2000 years of dehumanizing, hegemony of any of them has ended in the
harmful bleeding and purging,” 10 alongside with accretion and highlighting of its shortcomings,
vomiting and sweating. which led to an increasing rate of research and
A dialectical logic of mental-material development of the other alternative.14 Unlike in
relationship is required because it is the solely Natural Sciences, in Psychology the object of
able to support an integrative psychobiological research is also a reflexive subject. Therefore the
model for understanding depression. It would subjects reflect on their own objectivity and thus
start from the existence of different genetic change themselves due to new discoveries and
variants which sensitize people to the disturbing information. In addition, given the heterogeneity
life experiences that make them vulnerable to of the human being, each of the two paradigms
depression. It should rely on studies to identify are doomed to reach, sooner or later, an
biological mechanisms that contribute to unsatisfactory point.
depression by favoring the tendency to interpret The human (self-)reflexivity, as individuals
events in an extremely negative way and socio- and social groups, is the one that best explains
cultural factors which supply the content, the this perpetual metaphysical two-step oscillation
context and the triggering mechanisms.11 These between the two major paradigms of
mechanisms become completely meaningful understanding mental reality: Person Constructs
only within broader the evolutionist perspective. Reality (mentalism) versus Reality Constructs
Within such a model, the biological or genetic Person (materialism). There could be three
vulnerability (diathesis) is understood as possible hypotheses underlying this cyclic alternation.
predisposition for social influences and control “First, there might be some emotional or
by virtue of group selection ecology, the one conceptual threshold which is reached each time
which „has sculpted the perverse makeup which a community of psychologists look at human
manifests itself in our depressive lethargy, in our (and, therefore, their own) behavior through the
paralyzing anxiety, in the irritability which lens of either metaphysic for too long. Reaching
drives others away when we need them most, in the threshold would then result in these
our depressive resignation when success psychologists or the next generation of
repeatedly eludes us, and in the failure of our psychologists wearing the opposite lens. The
health when we lose the status, goals, or people second hypothesis is that there is no logical
who give us our sense of meaning and even our vocabulary, no metaphysic, available which
very sense of being.”12 Only such a complex and adequately captures the truth contained in both
culturally elevated view, which most of all could Person Constructs Reality and Reality Constructs
be empirically endorsed, supports the validity of Person models. Perhaps this is due to our
the absence of psychiatric illness.” 42 The instead of being pathologized could be very well
metaphysical ground of modern culture is based controlled and operated for the benefit of cultural
on tragic settings. Life on earth is doomed to development. “I understand depression to be
suffering and sorrow, with no sight for the beginning of an unfolding process of self-
exceptional and enlightening (emotional) states awareness, not the grim end of a disease process
of mind. It is obvious why, in medical world, (…) depression’s signs and symptoms can be
depression is seen as “a real disease, just as a used as opportunities rather than viewed as
heart attack is real. Depression produces physical, catastrophe and (…) clinically depressed and
emotional and thinking symptoms. Without ordinarily unhappy and confused people can
treatment, depression can last for years and can achieve greater understanding, wholeness, and
even end in suicide. With treatment, as many as fulfillment.” 46 This self-learning and self-
nine out of 10 people recover.”43 They recover developing process could be initiated and
from the clinical depression into “normal become real only if we become aware of the
neurosis” – as Sigmund Freud set the goal of underlying philosophical overview. The
therapy to “transforming neurotic misery into existential condition of a conscious being in the
common unhappiness”. world is a very disturbing and challenging
“Depression is not one thing; it is many situation. The entire history of philosophy, if not
things. Sometimes it is a disease, as in manic- exclusively, but importantly, could be seen “as a
depression; in this case, it comes and goes in diverse multitude of endeavors to find therapies
severe episodes which are impossible to stop or for such primordial suffering. As this is
control without the right medications. Sometimes constitutive of human existence and cognition,
it’s a reflection of personality traits, a tendency thus ontologically necessary, it cannot be cured.
to be anxious and moderately sad all the time, It can be integrated, considered as a cognitive
with brief periods of mood worsening. Sometimes, source, to be lived with rather than under. Thus
it’s just a reflection of life, and death, the we are, as Nietzsche says, always convalescents.”47
existential despair that we all experience, whether There is no way for psychology, the science of
we want to admit it or not.”44 The scientific and mental states, of thoughts and feelings, to
political community should understand that, circumvent the underlying philosophical truth
regardless of their illusory bias of certitude, to a of any of his theories on mental processes, of the
very high degree part mental disorder is not mind-body relationship, or of normal-abnormal
something that could be defined and evaluated significance. “There is no escape from philosophy.
with 100% percent accuracy. Being a cultural The question is only whether [a philosophy] is
phenomenon, it is relative at overall age level of good or bad, muddled or clear.”48
understanding and is shaped by this. “Mental But the appropriate cognitive therapy able to
disorder is what clinicians treat and researchers properly address the issue of depressive state
research and educators teach and insurance should contain at least a strong compound of
companies pay for.”45 It is not a reality in itself philosophical analysis, which if it is not existential
and for this reason the application of natural is at least strongly related to it. However, it
science methodology is limited. It is mandatory should, first and foremost, make use of the strong
for the present researcher community and for component of reflexivity, the one that provides
public perception to go beyond the positivist the metaphysical substratum of collective living
conception of statistically probing the studied identity. An individualist existentialism like
object and toward a more comprehensive rigorous self-referentiality is from the beginning
understanding of (non-clinical) depressive state a dead-end, if is not backed up by a self-reflexive
of consciousness. This perspective will expose perspective to include others as conditions of
the profound truth that depression is the possibility of one’s self-consciousness.
expression of a need for a comprehensive insight The entrenched image supported by the
into the state of a conscious being that lives in a hegemonic paradigm of technical natural science
colossal unknown universe. This psychological in psychology claims that only the cognitive and
disposition could prove a useful provision which behavioral approaches have empirical evidence
for their effectiveness. It conceals the truth that Most of us don’t despair, though, because we
psychodynamic therapies are empirically based. don’t know what it means to say that the world
In the case of the latter, there are strong findings is postmodern and God is dead. In fact, we know
that demonstrate patients seem to continue to it so well - that the world is postmodern and God
maintain therapeutic gains and even improve is dead–that we aren’t conscious of what we
their condition after treatment. These raises the know…”52
question whether “the efficiency of The postmodern Man, the darkest caricature
nonpsychodynamic therapies may be effective in of the Enlighten Man product of Renaissance has
part because the more skilled practitioners utilize dealt Reason for Illusion, the immaterial faith to
techniques that have long been central to material comfort and the elevated altruistic
psychodynamic theory and practice,”49 especially gratification for the grotesque self-satisfied
methods such as self-awareness and self- individualism. He is proud about its self-
examination. Achieving self-knowledge through considered superiority of its skeptic relativism
self-reflexivity is the (only) therapeutic and over believers’ absolute and his mingled
personal development method able to fully knowledge over rationalists’ rigor. He has access
exploit the structural existential reality of human at much knowledge that anyone had before, but
being. From this perspective „philosophy and he prefers the superficial information and denies
psychology are deeply connected in reflecting the access to real knowledge. The World returns
the task of developing through anxiety and to its unintelligible and hostile state as it was for
depression rather than against them. Philosophical the first men in the beginning of consciousness.
methods if worth their salt are therapies to get The ancestral depression and anxiety begin to
us unstuck from the horrors of suffering in master the human mind and emotions one more
anxiety and depression - as well as from such time.
‘truths’ as are supposed to eliminate In this valley of the shadow of death there is
uncertainty.”50 As a cognitive being, released a path for goodness and loving kindness in
from the implacable determinism of the organic rightful understanding of Life and Being, what
structure, Man is condemned to freedom of the Spirituality is truly about. The autopoiesis of
intention, to self-consciousness. Man makes his the living, the self-creative character of human
reality and makes himself by thinking. „Watch knowledge and evolution is a totally pleasingly
your thoughts, for they become words. Watch ground and aim for motivating the endeavor of
your words, for they become actions. Watch your life in the Universe. Self-reflexivity, as an ability
actions, for they become habits. Watch your of understanding the creative character of
habits, for they become your character. And knowing about the world and of self-awareness,
watch your character, for it becomes your destiny. and as an understanding of inter-relation of this
What we think, we become.”51 knowledge, is that level of consciousness which
The non-introspective living, devoid of can assure the balance of bio-psycho-social-
reflexivity, makes the individual a creature of cultural forces which tensional shape the human
impulses, whose life is chosen by the course of being. The present psychiatric affections should
events. Thinking as your surrounding be reinterpreted, and the primitive biomedical
environment and media suggest - that is over- model elevated to a bio-psycho-social-cultural
enhanced, flattering and illusory - leads to a self- paradigm. We may only hope that such a
deceptive and contingent construction of paradigm of the psychic diseases will be endorsed
personality. An exaggerated introspection of by cultural selection, if a similar evolutionary
brutal realism devoid of the creativity of utopia mechanism which insures the functioning and
leads to the worsening of fundamental anxiety survival of the living world, governs the
and depression (i.e. as of their fundamental development of social knowledge, the futile and
status of a being aware of its own existence.) “In ineffective directions ending in self-destruction.
a word, we are living in a postmodern world Otherwise the rise of a Prozac Mankind seems
where nothing is true and nothing is false; the imminent.
rational response to such a world is despair.
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