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Listed As A "Rare Disease" by The Office of Rare Diseases

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Listed as a “rare

disease” by
The Office of Rare
Diseases
Anthrax is an infectious disease caused by bacteria called Bacillus
anthracis. Infection in humans occurs in the skin, the gastrointestinal
tract, or the lungs.Its dated back in ancient rome.. It served as the
prototype for Koch's postulates regarding the cause of infectious
disease. The first vaccine containing live organisms was Louis
Pasteur's veterinary anthrax vaccine. In the 1900s, human inhalation
anthrax occurred in the United States among textile and tanning
workers, but the cases of the disease has declined. An outbreak of
inhalation anthrax occurred in Sverdlovsk near a Soviet military
microbiology facility in 1979. This epidemic represented the largest
outbreak of human inhalation anthrax in history. In October and
November 2001, 22 cases of confirmed or suspected inhalation and
cutaneous anthrax were reported associated with the intentional
release of the organism in the United States.
Symptoms of anthrax depend on the type of anthrax.
 
Symptoms of cutaneous anthrax:
• Blister or ulcer that later forms a black scab
• Blister or ulcer is usually surrounded by a lot of swelling
Symptoms of inhalation anthrax:
• Begins with fever, malaise, headache, cough, shortness of breath,
and chest pain
• Shock may occur later
Symptoms of gastrointestinal anthrax usually develop within one week
and can affect the mouth, esophagus, intestines, and colon. Symptoms
may include:
• Nausea and vomiting (the vomit may include blood)
• Anorexia
• Bloody diarrhea
Most people with anthrax are treated with antibiotics. Several antibiotics
are effective, including penicillin, doxycycline, and ciprofloxacin.
 
When treating inhalational anthrax, a combination of antibiotics is used.
Doctors often start treatment ciprofloxacin plus another drug, given
through a vein.
 
Cutaneous anthrax is treated with antibiotics taken by mouth,  for 7 to
10 days.
 
The length of treatment for inhalation anthrax is currently about 60
days, since it may take anthrax spores that long to grow.
 
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm
5653a1.htm
http://www.emergentbiosolutions.com/html/biothra
x.aspx

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