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    27 To Pee The Urinarysystemab

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    api-159564163
    The document discusses the structure and function of the urinary system. It describes the key components of the kidney including the renal cortex, medulla, nephrons, renal corpuscles and glomeruli. It explains how nephrons filter blood in the glomerulus to form urine, and how various tubules reabsorb essential molecules while others are excreted. The document also outlines the roles of the ureters, urinary bladder and urethra in collecting and storing urine before excretion from the body.

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    27 To Pee The Urinarysystemab

    Uploaded by

    api-159564163
    221 views38 pages
    The document discusses the structure and function of the urinary system. It describes the key components of the kidney including the renal cortex, medulla, nephrons, renal corpuscles and glomeruli. It explains how nephrons filter blood in the glomerulus to form urine, and how various tubules reabsorb essential molecules while others are excreted. The document also outlines the roles of the ureters, urinary bladder and urethra in collecting and storing urine before excretion from the body.

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    27 to pee the urinarysystemab

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    The document discusses the structure and function of the urinary system. It describes the key components of the kidney including the renal cortex, medulla, nephrons, renal corpuscles and glomeruli. It explains how nephrons filter blood in the glomerulus to form urine, and how various tubules reabsorb essential molecules while others are excreted. The document also outlines the roles of the ureters, urinary bladder and urethra in collecting and storing urine before excretion from the body.

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
    Download as ppt, pdf, or txt
    221 views38 pages

    27 To Pee The Urinarysystemab

    Uploaded by

    api-159564163
    The document discusses the structure and function of the urinary system. It describes the key components of the kidney including the renal cortex, medulla, nephrons, renal corpuscles and glomeruli. It explains how nephrons filter blood in the glomerulus to form urine, and how various tubules reabsorb essential molecules while others are excreted. The document also outlines the roles of the ureters, urinary bladder and urethra in collecting and storing urine before excretion from the body.

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
    Download as ppt, pdf, or txt
    of 38

    Urinary System

    To pee or not to pee.

    The Kidney

    Histology

    Renal Pyramidal Region


    Renal Cortex

    Renal Medulla

    Nephron (cortical region)


    Proximal Convoluted Tubule

    Distal Convoluted Tubule

    Renal Corpuscle with


    Glomerulus

    Collecting Duct

    Nephron (medullary region)


    Loop of Henle of
    Cortical Nephron
    Loop of Henle of
    Juxtaglomerular Nephron

    Collecting Duct

    Renal Capsule

    Glomeruli

    Collecting duct

    Renal Cortex

    Renal Corpuscle
    Distal Convoluted Tubule

    Glomerulus
    (with Podocytes)
    Glomerular capsule

    Proximal Convoluted Tubule

    Afferent & Efferent Arterioles

    Glomerular capsule

    Renal Corpuscle
    Glomerulus

    Glomerular capsule

    Capsular space

    Glomerulus
    Capsular Space

    Glomerular capsule

    Proximal and Distal Convoluted Tubules

    Podocytes
    Stellate epithelium that rest on top of the
    fesebtrated capillary basement membrane.
    Negatively charged, prevent small proteins
    and negatively charged organic ions from
    leaving the blood.

    Filtration
    1. Fenestrated capillaries block blood cells
    and platelets
    2. Thick basement membrane prevents
    large proteins (albumin) and organic
    anions from filtering out.
    Filtration slits of podocytes and organic
    anions from filtering out.

    Mesangium
    1. Between capillaries, can be mistaken from
    pericytes.
    Functions:

    a. support capillaries in within glomerulus

    b. Phagocytosis of protein and


    antigen/antibody complexes
    3. Secretion of immune system compounds such
    as prostaglandins and cytokines.
    4. Secrete erythropoietin

    Cells of the Juxtaglomerular Apparatus


    Cell

    Functionn

    Interglomerular mesangial cell

    Extraglomerular mesangial cell

    Juxtaglomerular (granular) cell


    Macula densa cells
    Myocyte (Pericytes)

    Support, filtration,
    phagocytosis.
    Contract with sympathetic
    stimulation. May assist
    communication between
    macula densa and afferent
    capillary
    Secrete renin
    Sense salt content
    Smooth muscle

    Diagram of renal corpuscle structure: A Renal corpuscle B Proximal tubule C


    Distal convoluted tubule D Juxtaglomerular apparatus 1. Basement membrane (Basal
    lamina) 2. Bowman's capsule parietal layer 3. Bowman's capsule visceral layer 3a.
    Pedicels (Foot processes from podocytes) 3b. Podocyte 4. Bowman's space (urinary
    space) 5a. Mesangium Intraglomerular cell 5b. Mesangium Extraglomerular cell 6.
    Granular cells (Juxtaglomerular cells) 7. Macula densa 8. Myocytes (smooth muscle) 9.
    Afferent arteriole 10. Glomerulus Capillaries 11. Efferent arteriole

    Juxtaglomerular apparatus

    Macula Densa

    Macula densa

    Macula Densa in Distal Convoluted Tubule

    Glomerular capsule

    Renal Pyramidal Region


    Renal Cortex

    Renal Medulla

    Renal Medulla

    CD
    ALH

    DLP

    Collecting Ducts & Loops of Henle


    Thin

    Thick

    Loop of Henle & Collecting Duct

    Collecting Ducts

    Terminal Renal Pyramid & Minor Calyx

    Papillary Collecting duct

    Transitional
    epithelium

    Minor
    calyx

    Transitional Epithelium of Renal Pelvis

    Urinary System
    Kidney

    Ureter

    Urinary Bladder

    Urethra

    Ureter

    Ureter

    Urinary Bladder
    Transitional epithelium
    Lamina propria
    Submucosa (dense
    irregular connective
    tissue)

    Smooth muscle
    (Detrusor muscle
    (3 layers)

    Adventitia

    Urinary Bladder
    Umbrella
    cells

    Intermediate
    region

    Basal cells

    Urinary Bladder
    Transitional epithelium

    Lamina propria

    Submucosa
    (dense irregular
    connective tissue)

    Urinary Bladder
    Submucosa

    Smooth muscle

    Adventitia

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