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| Status |
Public on Jun 20, 2006 |
| Title |
Gastric Bypass Human Obese Muscle |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Obesity results from a chronic imbalance between energy intake and energy expenditure, with excess calories stored as fat. As such, weight loss has long been considered as a primary goal of treatment for obesity. A surgical treatment of severe obesity such as gastric bypass provides the most dramatic reductions in body weight, and a well-known effect of weight loss is an improvement in insulin sensitivity. However, the molecular mechanism underlying this association remains unclear. Thus, we profiled skeletal muscle of morbidly obese patients before and after gastric bypass surgery. Results from this project will provide global patterns of gene expression with weight loss, which help to understand the pathogenesis of obesity at the molecular level.
Keywords: Time-Series
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| Overall design |
To identify responsive genes to weight loss.
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| Contributor(s) |
Houmard J |
| Citation(s) |
16849634 |
| |
| Submission date |
Jun 20, 2006 |
| Last update date |
Oct 01, 2019 |
| Contact name |
Eric P Hoffman |
| E-mail(s) |
ericphoffman@gmail.com
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| Organization name |
Binghamton University - SUNY
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| Department |
Pharmaceutical Sciences
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| Street address |
PO Box 6000
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| City |
Binghamton |
| State/province |
NY |
| ZIP/Postal code |
13902 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA95373 |