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Technologies and techniques
In this article series, Nature Reviews Molecular Cell Biology focuses on recent technological and technical advances and on their impact on diverse areas of molecular and cell biology. The articles highlight important biological issues, describe the technologies and techniques that were developed to tackle them and discuss the wealth of knowledge that using them has produced.
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Nobel Prize in Chemistry 2024
The 2024 Nobel Prize in Chemistry has been awarded to David Baker “for computational protein design” and to Demis Hassabis and John M. Jumper “for protein structure prediction”.
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Nobel Prize in Physiology or Medicine 2024
The 2024 Nobel Prize in Physiology or Medicine has been awarded jointly to Victor Ambros and Gary Ruvkun "for the discovery of microRNA and its role in post-transcriptional gene regulation".
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Liquid–liquid phase separation in cells
Multivalent interactions between biological molecules result in the formation of biomolecular condensates, a phenomenon known as Liquid–liquid phase separation (LLPS). Biomolecular condensates have important cellular and physiological functions, and aberration in LLPS can result in pathologies. This
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Cell death
A series of articles from Nature Reviews Molecular Cell Biology on cell death pathways, their mechanisms and their roles in physiology and disease.
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Post-translational modifications
The articles in this series discuss new insights that have been gained into how ‘old and new’ modifications are regulated and recognized, and how they crosstalk with one another to control fundamental biological processes.
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Structure–function
The functions of biomolecules, including lipids, nucleic acids and especially proteins are determined to a great extent by their structure. This structure–function relationship is a foundation of many physiological processes. In this article series, Nature Reviews Molecular Cell Biology collates Reviews that present important structural findings and illuminate their mechanistic and functional significance.
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Translation and protein quality control
A series of articles from Nature Reviews Molecular Cell Biology on protein synthesis and translation-associated protein quality control, and their deregulation in human disease.
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Metabolic signalling
Metabolic pathways are dynamically regulated to meet the energy needs of the cell and maintain cell and organismal homeostasis. This series features Review articles that discuss various aspects of the regulation of metabolic signalling, the interface between metabolic regulators and cellular processes and the implications of their deregulation for human diseases.
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Lipids and membranes
This article series brings together Reviews that focus on key advances in understanding membrane biology as well as the regulation and functions of their lipid components, including their roles as bioactive molecules and their interplay with metabolism.
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Adult stem cells
In this article series, Nature Reviews Molecular Cell Biology looks at the progress that has been made in identifying resident stem cells in different tissues and in characterizing these often-heterogeneous stem cell pools, as well as in understanding the intrinsic mechanisms and interactions with stem cell niches (the specialized microenvironments in which they reside) that regulate stem cell function.
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