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30 pages, 10836 KiB  
Article
A Preliminary Experimental and Numerical Analysis of a Novel Solar Dryer
by Pio Francesco Muciaccia, Alessandra Nigro, Alessia Aquilanti, Sebastiano Tomassetti, Matteo Muccioli and Giovanni Di Nicola
Energies 2024, 17(23), 6059; https://doi.org/10.3390/en17236059 - 2 Dec 2024
Viewed by 686
Abstract
In this study, a novel solar dryer is presented and analyzed experimentally and numerically. The proposed device is a small, passive, indirect solar dryer that works in an unconventional way. The product is mainly heated by irradiation from the walls of the drying [...] Read more.
In this study, a novel solar dryer is presented and analyzed experimentally and numerically. The proposed device is a small, passive, indirect solar dryer that works in an unconventional way. The product is mainly heated by irradiation from the walls of the drying chamber, while its moisture is removed by an airflow caused by natural convection. In addition, it is a low-cost solar dryer made of readily available materials and has a variable geometry that allows it to increase its thermal performance. Two types of experimental tests were conducted to analyze its performance. Thermal tests without load were carried out to assess the suitability of the drying chamber temperatures. Load tests with various masses and types of food were carried out to evaluate its drying performance. The results of the experimental tests demonstrated that the solar dryer achieved temperatures suitable for food drying and was able to dry the tested foods. Finally, a Computational Fluid Dynamics (CFD) model was developed to predict the performance of the proposed solar dryer. The validation of the numerical model with experimental data confirms their reliability in accurately predicting the temperatures within the dryer. Full article
(This article belongs to the Special Issue Advanced Solar Technologies and Thermal Energy Storage)
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Figure 1
<p>Newton Solar Dryer views (dimensions in mm): (<b>a</b>) left side view, (<b>b</b>) lateral view, (<b>c</b>) right side view, (<b>d</b>) top view.</p>
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<p>Photo of the Newton Solar Dryer.</p>
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<p>Comparison between NSC (<b>a</b>) and NSD (<b>b</b>). The cooking and drying chambers of the NSC and NSD, respectively, are highlighted with red dotted lines.</p>
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<p>Working schema of the Newton Solar Dryer.</p>
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<p>Details of the NSD base.</p>
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<p>Side door of the NSD (dimensions in mm).</p>
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<p>Experimental setup. <math display="inline"><semantics> <mrow> <msub> <mi>T</mi> <mrow> <mi>Air</mi> <mtext>_</mtext> <mi>outlet</mi> </mrow> </msub> </mrow> </semantics></math>: outlet air temperature from the drying chamber; <math display="inline"><semantics> <mrow> <msub> <mi>T</mi> <mi>Plate</mi> </msub> </mrow> </semantics></math>: metal plate temperature; <math display="inline"><semantics> <mrow> <msub> <mi>T</mi> <mi>Internal</mi> </msub> </mrow> </semantics></math>: air temperature inside the drying chamber; <math display="inline"><semantics> <mrow> <msub> <mi>T</mi> <mrow> <mi>Air</mi> <mtext>_</mtext> <mi>inlet</mi> </mrow> </msub> </mrow> </semantics></math>: inlet air temperature from the ambient; <math display="inline"><semantics> <mrow> <msub> <mi>T</mi> <mi>Glass</mi> </msub> </mrow> </semantics></math>: glass temperature; <math display="inline"><semantics> <mrow> <msub> <mi>T</mi> <mi>amb</mi> </msub> </mrow> </semantics></math>: ambient temperature; <math display="inline"><semantics> <mrow> <msub> <mi>G</mi> <mi>bn</mi> </msub> </mrow> </semantics></math>: direct normal irradiance.</p>
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<p>Scheme of the wooden structures for thermocouple supports. The lateral structure is placed at a distance of 120 mm from the central structure.</p>
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<p>Average environmental conditions during the tests: (<b>a</b>) direct normal solar irradiance, (<b>b</b>) ambient temperature, (<b>c</b>) wind speed, and (<b>d</b>) air humidity.</p>
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<p>Position of the thermocouples for the 17 February 2023 test: (<b>a</b>) in the central area of the drying chamber; (<b>b</b>) in the lateral area of the drying chamber; (<b>c</b>) on the rear metal plate; (<b>d</b>) on the front metal plate. The dimensions are in mm. The thermocouple supports and the glass plates are highlighted in red and blue, respectively.</p>
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<p>Position of the thermocouples for the 17 February 2023 test: (<b>a</b>) in the central area of the drying chamber; (<b>b</b>) in the lateral area of the drying chamber; (<b>c</b>) on the rear metal plate; (<b>d</b>) on the front metal plate. The dimensions are in mm. The thermocouple supports and the glass plates are highlighted in red and blue, respectively.</p>
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<p>Position of the thermocouples for the March 2023 tests: (<b>a</b>) in the central area of the drying chamber; (<b>b</b>) in the lateral area of the drying chamber; (<b>c</b>) on the rear metal plate; (<b>d</b>) on the front metal plate. The dimensions are in mm. The thermocouple supports and the glass plates are highlighted in red and blue, respectively.</p>
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<p>Temperature trends recorded during the thermal test of 22 March 2023: (<b>a</b>) internal temperatures inside the drying chamber; (<b>b</b>) plate temperatures. The ambient temperature and direct solar irradiance trends are also reported. The positions of the recorded temperatures are shown in <a href="#energies-17-06059-f011" class="html-fig">Figure 11</a>.</p>
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<p>Position of the thermocouples for the 18 July 2023 test: (<b>a</b>) at the dryer base; (<b>b</b>) in the central area of the drying chamber; (<b>c</b>) in the lateral area of the drying chamber. The dimensions are in mm. The thermocouple supports and the glass plates are highlighted in red and blue, respectively.</p>
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<p>Temperature trends recorded during the thermal test of 18 July 2023: (<b>a</b>) temperatures inside the drying chamber; (<b>b</b>) temperatures on the plates; (<b>c</b>) temperatures on the glass panes; (<b>d</b>) temperatures of the air entering and leaving the drying chamber. The ambient temperature and direct solar irradiance trends are also reported. The positions of the recorded temperatures are shown in <a href="#energies-17-06059-f013" class="html-fig">Figure 13</a>.</p>
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<p>Trays with apple slices loaded inside the drying chamber.</p>
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<p>Position of thermocouples during apple drying tests: (<b>a</b>) dryer base and (<b>b</b>) drying chamber central area. The dimensions are in mm. The glass plates are highlighted in blue.</p>
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<p>Position of thermocouples during pea drying tests: (<b>a</b>) dryer base and (<b>b</b>) drying chamber central area. The dimensions are in mm. The glass plates are highlighted in blue.</p>
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<p>View of spatial discretization: (<b>a</b>) computational domain and boundaries and (<b>b</b>) mesh used to perform the numerical analysis.</p>
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<p>Temperature distribution (in °C) on (<b>a</b>) central plane and (<b>b</b>) lateral plane.</p>
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<p>Velocity magnitude distribution (in m/s) on (<b>a</b>) central plane and (<b>b</b>) lateral plane.</p>
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<p>Stream traces on (<b>a</b>) central plane and (<b>b</b>) lateral plane.</p>
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28 pages, 9539 KiB  
Article
Improved Fracture Permeability Evaluation Model for Granite Reservoirs in Marine Environments: A Case Study from the South China Sea
by Jianhong Guo, Baoxiang Gu, Hengyang Lv, Zuomin Zhu and Zhansong Zhang
J. Mar. Sci. Eng. 2024, 12(10), 1868; https://doi.org/10.3390/jmse12101868 - 18 Oct 2024
Cited by 1 | Viewed by 692
Abstract
Permeability is a crucial parameter in the exploration and development of oil and gas reservoirs, particularly in unconventional ones, where fractures significantly influence storage capacity and fluid flow. This study investigates the fracture permeability of granite reservoirs in the South China Sea, introducing [...] Read more.
Permeability is a crucial parameter in the exploration and development of oil and gas reservoirs, particularly in unconventional ones, where fractures significantly influence storage capacity and fluid flow. This study investigates the fracture permeability of granite reservoirs in the South China Sea, introducing an enhanced evaluation model for planar fracture permeability based on Darcy’s law and Poiseuille’s law. The model incorporates factors such as fracture heterogeneity, tortuosity, angle, and aperture to improve permeability assessments. Building on a single-fracture model, this research integrates mass transfer equations and trigonometric functions to assess intersecting fractures’ permeability. Numerical simulations explore how tortuosity, angle, and aperture affect individual fracture permeability and the influence of relative positioning in intersecting fractures. The model makes key assumptions, including minimal consideration of horizontal stress and the assumption of unidirectional laminar flow in cross-fractures. Granite outcrop samples were systematically collected, followed by full-diameter core drilling. A range of planar models with varying fracture apertures were designed, and permeability measurements were conducted using the AU-TOSCAN-II multifunctional core scanner with a steady-state gas injection method. The results showed consistency between the improved model and experimental findings regarding the effects of fracture aperture and angle on permeability, confirming the model’s accuracy in reflecting the fractures’ influence on reservoir flow capacity. For intersecting fractures, a comparative analysis of core X-ray computed tomography (X-CT) scanning results and experimental outcomes highlighted discrepancies between actual permeability measurements and theoretical simulations based on tortuosity and aperture variations. Limitations exist, particularly for cross-fractures, where quantifying complexity is challenging, leading to potential discrepancies between simulation and experimental results. Further comparisons between core experiments and logging responses are necessary for model refinement. In response to the challenges associated with evaluating absolute permeability in fractured reservoirs, this study presents a novel theoretical assessment model that considers both single and intersecting fractures. The model’s validity is demonstrated through actual core experiments, confirming the effectiveness of the single-fracture model while highlighting the need for further refinement of the dual-fracture model. The findings provide scientific support for the exploration and development of granite reservoirs in the South China Sea and establish a foundation for permeability predictions in other complex fractured reservoir systems, thereby advancing the field of fracture permeability assessment. Full article
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<p>Flow chart of this research.</p>
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<p>The classic flat plate fracture model.</p>
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<p>Flow diagram of curved roar.</p>
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<p>A sketch of roars and fractures. (<b>a</b>) A diagram of the curved connected pores in the rock mass; (<b>b</b>) The fracture in the fractured reservoir is regarded as a plane composed of <span class="html-italic">n</span> connected pores.</p>
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<p>A schematic diagram of laminar flow of liquid in an equal-diameter pipe.</p>
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<p>Model diagram of cross-fractures. (<b>a</b>) The case where fracture <math display="inline"><semantics> <mi>i</mi> </semantics></math> with an inclination angle of <math display="inline"><semantics> <mi>α</mi> </semantics></math> intersects fracture <math display="inline"><semantics> <mi>j</mi> </semantics></math> with an inclination angle of <math display="inline"><semantics> <mi>β</mi> </semantics></math>; (<b>b</b>) Pressure conduction diagram of cross-fractures.</p>
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<p>Numerical simulation results of single fracture. (<b>a</b>) Fracture porosity vs. permeability in homogeneous reservoir; (<b>b</b>) Fracture tortuosity vs. permeability (constant angle and aperture); (<b>c</b>) Fracture angle vs. permeability (constant tortuosity and aperture); (<b>d</b>) Fracture aperture vs. permeability (constant tortuosity and angle).</p>
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<p>Numerical simulation results of cross-fractures. (<b>a</b>) Two diagonally crossed fractures in the discrete fracture model under ideal conditions; (<b>b</b>) Relationship between fracture opening and rock mass permeability at fixed cross-fracture angles; (<b>c</b>) Model with one fixed fracture and the angle of the other increasing from 1° to 45°; (<b>d</b>) Relationship between fracture angle and rock mass permeability with varying single-fracture angle; (<b>e</b>) Model with fixed angles and radial horizontal movement of one fracture, shifting the intersection point; (<b>f</b>) Relationship between the relative position of the intersection and rock mass permeability.</p>
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<p>Granite sample collection. (<b>a</b>) Outcrop rock samples; (<b>b</b>) Outcrop sample collection.</p>
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<p>Full-diameter core drilling schematic diagram. (<b>a</b>) Drilling the operating table; (<b>b</b>) Core drilling finished product.</p>
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<p>Plate model apparatus diagram. (<b>a</b>) Flat plate model diagram; (<b>b</b>) Gasket schematic diagram; (<b>c</b>) Schematic diagram of the gripper.</p>
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<p>AUTOSCAN-II Core multifunctional scanner.</p>
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<p>Artificial fracture experiment process.</p>
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<p>X-CT scan imaging layout diagram.</p>
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<p>Experimental results of core permeability. (<b>a</b>) Measurement results for a core fracture aperture of 90 μm; (<b>b</b>) Permeability measurement results for the 90 μm fracture slab model; (<b>c</b>) Measurement results for a core fracture aperture of 140 μm; (<b>d</b>) Permeability measurement results for the 140 μm fracture slab model; (<b>e</b>) Measurement results for a core fracture aperture of 200 μm; (<b>f</b>) Permeability measurement results for the 200 μm fracture slab model; (<b>g</b>) Measurement results for a core fracture aperture of 250 μm; (<b>h</b>) Permeability measurement results for the 250 μm fracture slab model; (<b>i</b>) Measurement results for a core fracture aperture of 300 μm; (<b>j</b>) Permeability measurement results for the 300 μm fracture slab model. The non-English fonts in the lower left corner of Figures (<b>a</b>,<b>c</b>,<b>e</b>,<b>g</b>,<b>i</b>) are the recorded measurement point numbers and test times.</p>
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<p>Experimental results of core permeability. (<b>a</b>) Measurement results for a core fracture aperture of 90 μm; (<b>b</b>) Permeability measurement results for the 90 μm fracture slab model; (<b>c</b>) Measurement results for a core fracture aperture of 140 μm; (<b>d</b>) Permeability measurement results for the 140 μm fracture slab model; (<b>e</b>) Measurement results for a core fracture aperture of 200 μm; (<b>f</b>) Permeability measurement results for the 200 μm fracture slab model; (<b>g</b>) Measurement results for a core fracture aperture of 250 μm; (<b>h</b>) Permeability measurement results for the 250 μm fracture slab model; (<b>i</b>) Measurement results for a core fracture aperture of 300 μm; (<b>j</b>) Permeability measurement results for the 300 μm fracture slab model. The non-English fonts in the lower left corner of Figures (<b>a</b>,<b>c</b>,<b>e</b>,<b>g</b>,<b>i</b>) are the recorded measurement point numbers and test times.</p>
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<p>Fitting results of single-fracture aperture and permeability.</p>
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<p>Processing workflow and results of 3D digital core. (<b>a</b>) Overall view; (<b>b</b>) Reconstruction results of the core before fracturing; (<b>c</b>) Reconstruction results of the core after fracturing; (<b>d</b>) 2D cross-sectional image before filtering; (<b>e</b>) 2D cross-sectional image after filtering; (<b>f</b>) Filtered 2D cross-sectional image of the core before fracturing; (<b>g</b>) Filtered 2D cross-sectional image of the core after fracturing; (<b>h</b>) Preliminary extraction results of fractures; (<b>i</b>) Visualization results of the 3D fracture distribution based on threshold segmentation; (<b>j</b>) Processing results of the actual full-size core before fracturing; (<b>k</b>) Display of fracture morphology of the actual full-size core after fracturing (The different colors in the diagram represent different fracture groups).</p>
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<p>The relationship between porosity and permeability of full-size core before and after fracture formation.</p>
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<p>Calculated intersection diagram of fracture aperture and core fracture aperture.</p>
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<p>Cores with artificial fractures at different angles.</p>
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<p>CT scan results of X5 sample. (<b>a</b>) The cross-section of X5 sample; (<b>b</b>) Fracture structure diagram of X5 sample.</p>
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<p>The relationship between resistivity and porosity and permeability. (<b>a</b>) The relationship between porosity and resistivity; (<b>b</b>) The relationship between permeability and resistivity.</p>
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21 pages, 15945 KiB  
Article
Mechanisms of Proppant Transport in Rough Fractures of Offshore Unconventional Reservoirs: Shale and Tight Sandstone
by Biao Yin, Yishan Lou, Shanyong Liu and Peng Xu
J. Mar. Sci. Eng. 2024, 12(9), 1582; https://doi.org/10.3390/jmse12091582 - 7 Sep 2024
Viewed by 922
Abstract
After hydraulic fracturing, unconventional reservoirs frequently encounter challenges related to limited effective proppant support distance and suboptimal proppant placement. Due to the strong heterogeneity of offshore reservoirs, which causes varying fracture roughnesses depending on different lithologies, a systematic study of the relationship between [...] Read more.
After hydraulic fracturing, unconventional reservoirs frequently encounter challenges related to limited effective proppant support distance and suboptimal proppant placement. Due to the strong heterogeneity of offshore reservoirs, which causes varying fracture roughnesses depending on different lithologies, a systematic study of the relationship between roughness and proppant transport could optimize operational parameters. This study incorporates the box dimension method for fractal dimension analysis to quantify roughness in auto-correlated Gaussian distributed surfaces created by true triaxial tests. Combined with the numerical analysis of (computational fluid dynamics) CFD-DEM (discrete element method) for bidirectional coupling, the laws of proppant deposition and transport processes within fractures with different roughnesses are obtained through comparative verification simulations. The results show that for rougher fractures of shale, the proppants are transported farther, but at JRC_52, (joint roughness coefficient), where there may be plugging in curved areas, there is a risk of near-well blockages. Compared to the smooth model, fluctuations in JRC_28 (tight sandstone) drastically increase turbulent kinetic energy within the fracture, altering particle transport dynamics. Moreover, smaller proppants (d/w ≤ 0.3) exhibit better transport capacity due to gravity, but the conductivity of the proppant is limited when the particles are too small. A d/w of 0.4 is recommended to guarantee transport capacity and proppant efficiency near the well. Additionally, proppants injected sequentially from small to large in shale fractures offer optimal propping effects, and can take advantage of the better transport capacity of smaller proppants in rough fractures. The large proppant (d/w = 0.8) is primarily deposited by gravity and forms a sloping sand bed, which subsequently ensures the aperture of the fractures. This research provides a fresh perspective on the influence of fracture roughness on proppant transport in offshore unconventional reservoirs and offers valuable considerations for the order of proppant injection. Full article
(This article belongs to the Section Ocean Engineering)
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<p>CFD-DEM coupling process (<b>a</b>); schematic diagram of CFD-DEM coupling [<a href="#B26-jmse-12-01582" class="html-bibr">26</a>] (<b>b</b>).</p>
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<p>True triaxial test system and post-fracturing results of rock sample #1.</p>
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<p>Pump–pressure curves of the rock sample #1 (<b>a</b>); pump–pressure curves and result of the rock sample #3 after fracturing (<b>b</b>).</p>
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<p>Scanned fracture surfaces of two different rocks (<b>a</b>); calculation of the fractal dimensions (<b>b</b>).</p>
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<p>Histograms of fracture aperture and corresponding probability density fitted with a Gaussian curve.</p>
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<p>Comparison of typical values and equation-predicted JRC values [<a href="#B31-jmse-12-01582" class="html-bibr">31</a>] (<b>a</b>); the box dimension method calculates the fractal dimension D (<b>b</b>).</p>
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<p>Post-fracturing roughness identification results for two different lithologies.</p>
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<p>Establishment of 3D surfaces with different JRC (slight aperture range variation and pronounced undulations on rougher surfaces).</p>
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<p>The process of establishing the rough channel model of JRC_21.</p>
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<p>Flow channel model with five different roughnesses.</p>
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<p>Simulation of boundary conditions during proppant transportation.</p>
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<p>Verification of grid independence.</p>
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<p>Average settling velocity of the proppant (<b>a</b>); comparison of the experiment and simulation (<b>b</b>).</p>
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<p>Distribution curves of wall shear and turbulent kinetic energy for two different roughnesses.</p>
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<p>Contours of the proppant volume fraction under different roughness conditions (<b>a</b>); shear–stress distribution on P90 for different roughnesses (<b>b</b>).</p>
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<p>Deposition of particles in the DEM at different moments for tight sandstone (JRC_28).</p>
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<p>Deposition of particles in the DEM at different moments for shale (JRC_52).</p>
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<p>Transport and deposition curves of particles with different roughnesses.</p>
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<p>Distribution of proppant on two surfaces at different times (<b>a</b>); relationship between the number of collisions and roughness (<b>b</b>).</p>
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<p>Volume fraction distribution of the proppant for different particle sizes.</p>
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<p>Schematic diagram of the arrangement of different particle sizes in rough fractures.</p>
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<p>Velocity contours of mixed particle size transport in rough fractures (<b>a</b>); location and distribution of mixed particle size in rough fractures (<b>b</b>).</p>
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23 pages, 7312 KiB  
Article
Pressure Source Model of the Production Process of Natural Gas from Unconventional Reservoirs
by Boubacar Yarnangoré and Francisco Andrés Acosta-González
Processes 2024, 12(9), 1875; https://doi.org/10.3390/pr12091875 - 2 Sep 2024
Viewed by 742
Abstract
This work is focused on developing a computational model to predict the production rate and pressure evolution of natural gas from unconventional reservoirs, particularly shale gas deposits. The model is based on the principle of conservation of mechanical energy and was developed from [...] Read more.
This work is focused on developing a computational model to predict the production rate and pressure evolution of natural gas from unconventional reservoirs, particularly shale gas deposits. The model is based on the principle of conservation of mechanical energy and was developed from the transient solution of Bernoulli’s equation. This solution was obtained by computing the pressure evolution in the well resulting from the combined action of extracting the free gas and of gasification from kerogen. The transient behavior of gas production by hydraulic fracturing was calculated by numerically integrating Bernoulli’s equation. The curves representing gas flow evolution were considered as a series of stepwise steady states under a constant gas flow rate, similar to the pressure–time curves. These time steps were connected by instantaneous drops in pressure or gas flow rates. On the other hand, the delayed release of the adsorbed and dissolved gas in the kerogen was accurately calculated by introducing a semi-empirical gas pressure source term into the gas well pressure equation. The effect of this source is to gradually increase the gas pressure in the reservoir, emulating the gas release mechanisms from the organic matter. Model validation was based on production data from the unconventional reservoirs Eagle Ford, U.S.A., and Burgos basin, México. The initial measured gas production rate was used to determine a global friction factor of the gas flowing out from soil cracks and ducts. Additionally, measured production rate data were used to determine the coefficients of the source term function. Pearson correlation coefficients of 0.97 and 0.96 were obtained for Eagle Ford and Burgos basins data, respectively. In contrast, the corresponding coefficients calculated from the traditional Arps’ model were 0.89 and 0.5, respectively. The present pressure source model (PSM) represents a new approach to characterize the process of gas production from unconventional reservoirs, proving to be accurate in forecasting both the gas flow rate and pressure evolution during gas production. The postulated pressure source term was shown to mimic the desorption and diffusion kinetics, which release free gas from the kerogen. Full article
(This article belongs to the Section Materials Processes)
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<p>Measured gas production flow rate and pressure drop and the corresponding smoothed curves for wells (<b>a</b>) “A” and (<b>b</b>) “B”. Data points from Ref. [<a href="#B7-processes-12-01875" class="html-bibr">7</a>].</p>
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<p>(<b>a</b>) Schematic representation of a shale gas well, indicating control points 1, 2′, and 2 for the application of Bernoulli’s equation. (<b>b</b>) Simplified representation of gas flow ducts.</p>
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<p>Hydraulic resistance diagram for an unconventional natural gas well.</p>
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<p>Representation of a gas flow rate curve using stepwise steady states.</p>
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<p>Algorithms for calculating the gas production parameters in the well: (<b>a</b>) the flow diagram for the calculation of the friction coefficient (K’), (<b>b</b>) the flow diagram for the determination of the coefficients of the pressure source term model (B, C, a, and b).</p>
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<p>Comparison of smoothed data and calculated production curves using pressure p<sub>1</sub> that was computed from Equation (7). (<b>a</b>) Well “A” and (<b>b</b>) well “B”.</p>
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<p>Comparison of smoothed data and calculated gas flow rate curves using pressure p<sub>1</sub> that was computed from Equation (10). (<b>a</b>) Well “A” and (<b>b</b>) well “B”.</p>
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<p>Log–log plots comparing the smoothed data and computed curves of the gas flow rate for (<b>a</b>) well “A” and (<b>b</b>) well “B”, and of the gas pressure drop for (<b>c</b>) well “A” and (<b>d</b>) well “B”. Computed results were obtained using Equation (10) for gas pressure. Calculated curves are extrapolated to long times, anticipating the lifetime of each well.</p>
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<p>Computed sensitivity analysis of gas flow rate to three main parameters: (<b>a</b>) pipe diameter, (<b>b</b>) well depth, and (<b>c</b>) well temperature.</p>
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<p>Comparison of Arps’ decline curves with smoothed data curves and PSM curves for (<b>a</b>) well “A” and (<b>b</b>) well “B”.</p>
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<p>Comparison between the computed gas flow rate curves obtained with different models, including our pressure source model. The smoothed measurement data are remarkably better represented by the PSM.</p>
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<p>Computed pressure source term for both wells, as a function of: (<b>a</b>) pressure drop, p<sub>1</sub>-p<sub>2</sub>, and (<b>b</b>) free gas relative pressure decrease, X<sub>1</sub>, defined by Equation (15).</p>
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<p>Plots of gas flow rate versus gas pressure drop comparing smoothed data and PSM curves for both wells.</p>
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<p>Schematic representation of interconnected compressors through a safety valve to explain its analogy with unconventional natural gas reservoirs.</p>
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<p>Schematic representation of the evolution of the rates of evaporation and condensation of methane during natural gas production. The pressure source term depends on the difference between these rates.</p>
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29 pages, 3922 KiB  
Article
Integrating AI and Blockchain for Enhanced Data Security in IoT-Driven Smart Cities
by Burhan Ul Islam Khan, Khang Wen Goh, Abdul Raouf Khan, Megat F. Zuhairi and Mesith Chaimanee
Processes 2024, 12(9), 1825; https://doi.org/10.3390/pr12091825 - 27 Aug 2024
Viewed by 2582
Abstract
Blockchain is recognized for its robust security features, and its integration with Internet of Things (IoT) systems presents scalability and operational challenges. Deploying Artificial Intelligence (AI) within blockchain environments raises concerns about balancing rigorous security requirements with computational efficiency. The prime motivation resides [...] Read more.
Blockchain is recognized for its robust security features, and its integration with Internet of Things (IoT) systems presents scalability and operational challenges. Deploying Artificial Intelligence (AI) within blockchain environments raises concerns about balancing rigorous security requirements with computational efficiency. The prime motivation resides in integrating AI with blockchain to strengthen IoT security and withstand multiple variants of lethal threats. With the increasing number of IoT devices, there has also been a spontaneous increase in security vulnerabilities. While conventional security methods are inadequate for the diversification of IoT devices, adopting AI can assist in identifying and mitigating such threats in real time, whereas integrating AI with blockchain can offer more intelligent decentralized security measures. The paper contributes to a three-layered architecture encompassing the device/sensory, edge, and cloud layers. This structure supports a novel method for assessing legitimacy scores and serves as an initial security measure. The proposed scheme also enhances the architecture by introducing an Ethereum-based data repositioning framework as a potential trapdoor function, ensuring maximal secrecy. To complement this, a simplified consensus module generates a conclusive evidence matrix, bolstering accountability. The model also incorporates an innovative AI-based security optimization utilizing an unconventional neural network model that operates faster and is enhanced with metaheuristic algorithms. Comparative benchmarks demonstrate that our approach results in a 48.5% improvement in threat detection accuracy and a 23.5% reduction in processing time relative to existing systems, marking significant advancements in IoT security for smart cities. Full article
(This article belongs to the Section Advanced Digital and Other Processes)
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<p>Architecture of proposed framework.</p>
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<p>Proposed AI model.</p>
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<p>Predictive accuracy for AI approaches.</p>
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<p>Processing time for AI approaches.</p>
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<p>Detection accuracy for AI approaches.</p>
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<p>Transaction throughput for blockchain approaches [<a href="#B16-processes-12-01825" class="html-bibr">16</a>,<a href="#B17-processes-12-01825" class="html-bibr">17</a>,<a href="#B18-processes-12-01825" class="html-bibr">18</a>,<a href="#B19-processes-12-01825" class="html-bibr">19</a>,<a href="#B20-processes-12-01825" class="html-bibr">20</a>,<a href="#B21-processes-12-01825" class="html-bibr">21</a>,<a href="#B22-processes-12-01825" class="html-bibr">22</a>,<a href="#B23-processes-12-01825" class="html-bibr">23</a>,<a href="#B24-processes-12-01825" class="html-bibr">24</a>,<a href="#B25-processes-12-01825" class="html-bibr">25</a>,<a href="#B26-processes-12-01825" class="html-bibr">26</a>,<a href="#B27-processes-12-01825" class="html-bibr">27</a>].</p>
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<p>Resource consumption for blockchain approaches [<a href="#B16-processes-12-01825" class="html-bibr">16</a>,<a href="#B17-processes-12-01825" class="html-bibr">17</a>,<a href="#B18-processes-12-01825" class="html-bibr">18</a>,<a href="#B19-processes-12-01825" class="html-bibr">19</a>,<a href="#B20-processes-12-01825" class="html-bibr">20</a>,<a href="#B21-processes-12-01825" class="html-bibr">21</a>,<a href="#B22-processes-12-01825" class="html-bibr">22</a>,<a href="#B23-processes-12-01825" class="html-bibr">23</a>,<a href="#B24-processes-12-01825" class="html-bibr">24</a>,<a href="#B25-processes-12-01825" class="html-bibr">25</a>,<a href="#B26-processes-12-01825" class="html-bibr">26</a>,<a href="#B27-processes-12-01825" class="html-bibr">27</a>].</p>
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<p>Confirmation time for blockchain approaches [<a href="#B16-processes-12-01825" class="html-bibr">16</a>,<a href="#B17-processes-12-01825" class="html-bibr">17</a>,<a href="#B18-processes-12-01825" class="html-bibr">18</a>,<a href="#B19-processes-12-01825" class="html-bibr">19</a>,<a href="#B20-processes-12-01825" class="html-bibr">20</a>,<a href="#B21-processes-12-01825" class="html-bibr">21</a>,<a href="#B22-processes-12-01825" class="html-bibr">22</a>,<a href="#B23-processes-12-01825" class="html-bibr">23</a>,<a href="#B24-processes-12-01825" class="html-bibr">24</a>,<a href="#B25-processes-12-01825" class="html-bibr">25</a>,<a href="#B26-processes-12-01825" class="html-bibr">26</a>,<a href="#B27-processes-12-01825" class="html-bibr">27</a>].</p>
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<p>Detection accuracy for blockchain approaches [<a href="#B16-processes-12-01825" class="html-bibr">16</a>,<a href="#B17-processes-12-01825" class="html-bibr">17</a>,<a href="#B18-processes-12-01825" class="html-bibr">18</a>,<a href="#B19-processes-12-01825" class="html-bibr">19</a>,<a href="#B20-processes-12-01825" class="html-bibr">20</a>,<a href="#B21-processes-12-01825" class="html-bibr">21</a>,<a href="#B22-processes-12-01825" class="html-bibr">22</a>,<a href="#B23-processes-12-01825" class="html-bibr">23</a>,<a href="#B24-processes-12-01825" class="html-bibr">24</a>,<a href="#B25-processes-12-01825" class="html-bibr">25</a>,<a href="#B26-processes-12-01825" class="html-bibr">26</a>,<a href="#B27-processes-12-01825" class="html-bibr">27</a>].</p>
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<p>Processing time for blockchain approaches [<a href="#B16-processes-12-01825" class="html-bibr">16</a>,<a href="#B17-processes-12-01825" class="html-bibr">17</a>,<a href="#B18-processes-12-01825" class="html-bibr">18</a>,<a href="#B19-processes-12-01825" class="html-bibr">19</a>,<a href="#B20-processes-12-01825" class="html-bibr">20</a>,<a href="#B21-processes-12-01825" class="html-bibr">21</a>,<a href="#B22-processes-12-01825" class="html-bibr">22</a>,<a href="#B23-processes-12-01825" class="html-bibr">23</a>,<a href="#B24-processes-12-01825" class="html-bibr">24</a>,<a href="#B25-processes-12-01825" class="html-bibr">25</a>,<a href="#B26-processes-12-01825" class="html-bibr">26</a>,<a href="#B27-processes-12-01825" class="html-bibr">27</a>].</p>
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14 pages, 1233 KiB  
Article
Optimizing Artificial Neural Networks to Minimize Arithmetic Errors in Stochastic Computing Implementations
by Christiam F. Frasser, Alejandro Morán, Vincent Canals, Joan Font, Eugeni Isern, Miquel Roca and Josep L. Rosselló
Electronics 2024, 13(14), 2846; https://doi.org/10.3390/electronics13142846 - 19 Jul 2024
Viewed by 831
Abstract
Deploying modern neural networks on resource-constrained edge devices necessitates a series of optimizations to ready them for production. These optimizations typically involve pruning, quantization, and fixed-point conversion to compress the model size and enhance energy efficiency. While these optimizations are generally adequate for [...] Read more.
Deploying modern neural networks on resource-constrained edge devices necessitates a series of optimizations to ready them for production. These optimizations typically involve pruning, quantization, and fixed-point conversion to compress the model size and enhance energy efficiency. While these optimizations are generally adequate for most edge devices, there exists potential for further improving the energy efficiency by leveraging special-purpose hardware and unconventional computing paradigms. In this study, we explore stochastic computing neural networks and their impact on quantization and overall performance concerning weight distributions. When arithmetic operations such as addition and multiplication are executed by stochastic computing hardware, the arithmetic error may significantly increase, leading to a diminished overall accuracy. To bridge the accuracy gap between a fixed-point model and its stochastic computing implementation, we propose a novel approximate arithmetic-aware training method. We validate the efficacy of our approach by implementing the LeNet-5 convolutional neural network on an FPGA. Our experimental results reveal a negligible accuracy degradation of merely 0.01% compared with the floating-point counterpart, while achieving a substantial 27× speedup and 33× enhancement in energy efficiency compared with other FPGA implementations. Additionally, the proposed method enhances the likelihood of selecting optimal LFSR seeds for stochastic computing systems. Full article
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<p>Mean squared error associated with the stochastic multiplication of two bipolar variables.</p>
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<p>Average mean squared error associated with the bipolar multiplication considering the several input and weight probability density functions.</p>
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<p>Weight distribution for the CNN implemented in [<a href="#B12-electronics-13-02846" class="html-bibr">12</a>].</p>
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<p>Number of seeds generating different accuracy levels in the SC-CNN study presented in [<a href="#B12-electronics-13-02846" class="html-bibr">12</a>]; 80% of seeds produce an accuracy smaller than 0.95.</p>
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<p>Stochastic computing aware training flow chart.</p>
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<p>Weight distribution for several values of <math display="inline"><semantics> <msub> <mi>n</mi> <mi>σ</mi> </msub> </semantics></math> after applying weight clamping three consecutive times.</p>
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<p>Width factor and rounding rate hyperparameter setup for our experiment.</p>
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<p>Fully parallel stochastic CNN architecture [<a href="#B12-electronics-13-02846" class="html-bibr">12</a>].</p>
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<p>Weight distribution after the arithmetic aware training.</p>
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<p>Number of LFSR seeds producing various accuracies for different bit precisions.</p>
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29 pages, 6132 KiB  
Review
Smartphone Prospects in Bridge Structural Health Monitoring, a Literature Review
by Ekin Ozer and Rolands Kromanis
Sensors 2024, 24(11), 3287; https://doi.org/10.3390/s24113287 - 21 May 2024
Cited by 2 | Viewed by 2053
Abstract
Bridges are critical components of transportation networks, and their conditions have effects on societal well-being, the economy, and the environment. Automation needs in inspections and maintenance have made structural health monitoring (SHM) systems a key research pillar to assess bridge safety/health. The last [...] Read more.
Bridges are critical components of transportation networks, and their conditions have effects on societal well-being, the economy, and the environment. Automation needs in inspections and maintenance have made structural health monitoring (SHM) systems a key research pillar to assess bridge safety/health. The last decade brought a boom in innovative bridge SHM applications with the rise in next-generation smart and mobile technologies. A key advancement within this direction is smartphones with their sensory usage as SHM devices. This focused review reports recent advances in bridge SHM backed by smartphone sensor technologies and provides case studies on bridge SHM applications. The review includes model-based and data-driven SHM prospects utilizing smartphones as the sensing and acquisition portal and conveys three distinct messages in terms of the technological domain and level of mobility: (i) vibration-based dynamic identification and damage-detection approaches; (ii) deformation and condition monitoring empowered by computer vision-based measurement capabilities; (iii) drive-by or pedestrianized bridge monitoring approaches, and miscellaneous SHM applications with unconventional/emerging technological features and new research domains. The review is intended to bring together bridge engineering, SHM, and sensor technology audiences with decade-long multidisciplinary experience observed within the smartphone-based SHM theme and presents exemplary cases referring to a variety of levels of mobility. Full article
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<p>A timeline of smartphone evolution from its advent to complex and large-scale SHM research (2007 to 2024), examples above refer to in [<a href="#B27-sensors-24-03287" class="html-bibr">27</a>,<a href="#B28-sensors-24-03287" class="html-bibr">28</a>,<a href="#B29-sensors-24-03287" class="html-bibr">29</a>,<a href="#B31-sensors-24-03287" class="html-bibr">31</a>,<a href="#B32-sensors-24-03287" class="html-bibr">32</a>,<a href="#B33-sensors-24-03287" class="html-bibr">33</a>,<a href="#B34-sensors-24-03287" class="html-bibr">34</a>,<a href="#B35-sensors-24-03287" class="html-bibr">35</a>,<a href="#B36-sensors-24-03287" class="html-bibr">36</a>,<a href="#B37-sensors-24-03287" class="html-bibr">37</a>,<a href="#B38-sensors-24-03287" class="html-bibr">38</a>,<a href="#B39-sensors-24-03287" class="html-bibr">39</a>,<a href="#B40-sensors-24-03287" class="html-bibr">40</a>,<a href="#B42-sensors-24-03287" class="html-bibr">42</a>], respectively.</p>
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<p>Level of mobilities (LoMs) observed on a smartphone-engaged bridge monitoring ecosystem.</p>
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<p>Spatial footprint comparison for LoMs.</p>
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<p>Conceptual breakdown of smartphone components.</p>
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<p>Bridge cable installation of smartphone sensor: smartphone vibration frequency comparisons with the reference data (<b>a</b>,<b>b</b>) and sensor configuration (<b>c</b>), Yu et al. (2015) [<a href="#B32-sensors-24-03287" class="html-bibr">32</a>].</p>
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<p>Image frame with an ROI (<b>left</b>) and ROI with a target (<b>right</b>) [<a href="#B82-sensors-24-03287" class="html-bibr">82</a>].</p>
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<p>A vehicle–bridge interaction model used for simulating the indirect response, Zhu and Malekjafarian (2019) [<a href="#B120-sensors-24-03287" class="html-bibr">120</a>].</p>
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<p>CV-based system for measurement collection of the Wilford Suspension bridge.</p>
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<p>A sketch of the Wilford Suspension bridge with the locations of targets (T<math display="inline"><semantics> <mrow> <mi>i</mi> </mrow> </semantics></math>, where <math display="inline"><semantics> <mrow> <mi>i</mi> <mo>=</mo> <mn>1</mn> <mo>,</mo> <mo> </mo> <mn>2</mn> <mo>,</mo> <mo> </mo> <mo>…</mo> <mo>,</mo> <mo> </mo> <mn>9</mn> </mrow> </semantics></math>).</p>
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<p>Vertical displacement time-history for the selected activity (<b>left</b>) and power spectrum density plot (<b>right</b>).</p>
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<p>The mode shape of the bridge at its first vertical frequency.</p>
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<p>(<b>a</b>) Mudd–Schapiro Bridge, (<b>b</b>) accelerometer instrumentation, (<b>c</b>) sample smartphone measurement, (<b>d</b>) its frequency spectrum, and (<b>e</b>) and the comparison of crowdsourcing-identified modal frequency values with reference tests [<a href="#B34-sensors-24-03287" class="html-bibr">34</a>].</p>
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<p>Smartphone-based SHM frameworks for (<b>a</b>) spatiotemporally uncontrolled [<a href="#B55-sensors-24-03287" class="html-bibr">55</a>] and (<b>b</b>) directionally distorted [<a href="#B56-sensors-24-03287" class="html-bibr">56</a>] and (<b>c</b>) and indirectly retrieved vibration data [<a href="#B57-sensors-24-03287" class="html-bibr">57</a>].</p>
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<p>(<b>a</b>) Overall distribution of smartphone-based bridge monitoring sample studies according to their LoM context; (<b>b</b>–<b>d</b>) yearly publication trends among LoM1, LoM2, and LoM3, respectively.</p>
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<p>A vision of collective and connected smartphone applications for bridge SHM.</p>
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27 pages, 3850 KiB  
Article
Policy Assessment for Energy Transition to Zero- and Low-Emission Technologies in Pickup Trucks: Evidence from Mexico
by Julieth Stefany Garcia, Laura Milena Cárdenas, Jose Daniel Morcillo and Carlos Jaime Franco
Energies 2024, 17(10), 2386; https://doi.org/10.3390/en17102386 - 15 May 2024
Viewed by 1220
Abstract
The transport sector is under scrutiny because of its significant greenhouse gas emissions. Essential strategies, particularly the adoption of zero- and low-emission vehicles powered by electricity, are crucial for mitigating emissions in road transport. Pickups, which are integral to Mexico’s fleet, contribute to [...] Read more.
The transport sector is under scrutiny because of its significant greenhouse gas emissions. Essential strategies, particularly the adoption of zero- and low-emission vehicles powered by electricity, are crucial for mitigating emissions in road transport. Pickups, which are integral to Mexico’s fleet, contribute to such emissions. Thus, implementing effective policies targeting pickups is vital for reducing air pollution and aligning with Mexico’s decarbonization objectives. This paper presents a simulation model based on system dynamics to represent the adoption process of zero- and low-emission vehicles, with a focus on pickups and utilizing data from the Mexican case. Three policy evaluation scenarios are proposed based on the simulation model: business as usual; disincentives for zero- and low-emission vehicles; and incentives for unconventional vehicles. One of the most significant findings from this study is that even in a scenario with a greater number of vehicles in circulation, if the technology is fully electric, the environmental impact in terms of emissions is lower. Additionally, a comprehensive sensitivity analysis spanning a wide spectrum is undertaken through an extensive computational process, yielding multiple policy scenarios. The analysis indicates that to achieve a maximal reduction in the country’s emissions, promoting solely hybrid electric vehicles and plug-in hybrid electric vehicles is advisable, whereas internal combustion engines, vehicular natural gas, and battery electric vehicles should be discouraged. Full article
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<p>Fleet distribution in Mexico in 2019. Source: Created by the authors based on [<a href="#B9-energies-17-02386" class="html-bibr">9</a>].</p>
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<p>Model structure.</p>
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<p>Results of the BAU scenario divided into four sections, which are listed as follows: (<b>a</b>) simulation of the projected fleet; (<b>b</b>) number of chargers required for the operation of the battery fleet; (<b>c</b>) CAPEX vehicle cost based on policy actions; and (<b>d</b>) accumulated CO<sub>2</sub> emissions by technology for this scenario.</p>
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<p>Results of the No Transition scenario divided into four sections, which are listed as follows: (<b>a</b>) simulation of the projected fleet; (<b>b</b>) number of chargers required for the operation of the battery fleet; (<b>c</b>) CAPEX vehicle cost based on policy actions; and (<b>d</b>) accumulated CO<sub>2</sub> emissions by technology for this scenario.</p>
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<p>Results of the New Incentives scenario divided into four sections, which are listed as follows: (<b>a</b>) simulation of the projected fleet; (<b>b</b>) number of chargers required for the operation of the battery fleet; (<b>c</b>) CAPEX vehicle cost based on policy actions; and (<b>d</b>) accumulated CO<sub>2</sub> emissions by technology for this scenario.</p>
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<p>Comparison of three defined scenarios for two specified indicators. (<b>a</b>) Projection of the number of pickup trucks until 2050. (<b>b</b>) Behavior of emissions for each of the scenarios.</p>
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<p>Results of the best-case scenario divided into three sections, which are listed as follows: (<b>a</b>) simulation of the projected fleet; (<b>b</b>) CAPEX vehicle cost based on policy actions; (<b>c</b>) accumulated CO<sub>2</sub> emissions by technology; and (<b>d</b>) charging infrastructure evolution.</p>
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21 pages, 1489 KiB  
Article
ECHO: Energy-Efficient Computation Harnessing Online Arithmetic—An MSDF-Based Accelerator for DNN Inference
by Muhammad Sohail Ibrahim, Muhammad Usman and Jeong-A Lee
Electronics 2024, 13(10), 1893; https://doi.org/10.3390/electronics13101893 - 11 May 2024
Cited by 1 | Viewed by 1195
Abstract
Deep neural network (DNN) inference demands substantial computing power, resulting in significant energy consumption. A large number of negative output activations in convolution layers are rendered zero due to the invocation of the ReLU activation function. This results in a substantial number of [...] Read more.
Deep neural network (DNN) inference demands substantial computing power, resulting in significant energy consumption. A large number of negative output activations in convolution layers are rendered zero due to the invocation of the ReLU activation function. This results in a substantial number of unnecessary computations that consume significant amounts of energy. This paper presents ECHO, an accelerator for DNN inference designed for computation pruning, utilizing an unconventional arithmetic paradigm known as online/most significant digit first (MSDF) arithmetic, which performs computations in a digit-serial manner. The MSDF digit-serial computation of online arithmetic enables overlapped computation of successive operations, leading to substantial performance improvements. The online arithmetic, coupled with a negative output detection scheme, facilitates early and precise recognition of negative outputs. This, in turn, allows for the timely termination of unnecessary computations, resulting in a reduction in energy consumption. The implemented design has been realized on the Xilinx Virtex-7 VU3P FPGA and subjected to a comprehensive evaluation through a rigorous comparative analysis involving widely used performance metrics. The experimental results demonstrate promising power and performance improvements compared to contemporary methods. In particular, the proposed design achieved average improvements in power consumption of up to 81%, 82.9%, and 40.6% for VGG-16, ResNet-18, and ResNet-50 workloads compared to the conventional bit-serial design, respectively. Furthermore, significant average speedups of 2.39×, 2.6×, and 2.42× were observed when comparing the proposed design to conventional bit-serial designs for the VGG-16, ResNet-18, and ResNet-50 models, respectively. Full article
(This article belongs to the Section Circuit and Signal Processing)
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<p>A typical convolutional neural network: VGG-16. The convolution layers with a <math display="inline"><semantics> <mrow> <mn>3</mn> <mo>×</mo> <mn>3</mn> </mrow> </semantics></math> kernel are shown in yellow, the maxpooling layer is represented in orange, and the fully connected layers are presented in purple.</p>
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<p>The rectified linear unit (ReLU) activation function.</p>
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<p>Timing characteristics of online operation with <math display="inline"><semantics> <mrow> <mi>δ</mi> <mo>=</mo> <mn>3</mn> </mrow> </semantics></math>.</p>
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<p>Basic components: (<b>a</b>) online serial–parallel multiplier [<a href="#B49-electronics-13-01893" class="html-bibr">49</a>], where <span class="html-italic">x</span> is the serial input and <span class="html-italic">Y</span> is the parallel output; (<b>b</b>) online adder [<a href="#B50-electronics-13-01893" class="html-bibr">50</a>].</p>
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<p>Circuit block diagram for an example SOP computation.</p>
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<p>Bit-level computation pattern of the SOP in the example <math display="inline"><semantics> <mrow> <mi>Z</mi> <mo>=</mo> <mo>(</mo> <mi>A</mi> <mo>×</mo> <mi>B</mi> <mo>+</mo> <mi>C</mi> <mo>×</mo> <mi>D</mi> <mo>)</mo> </mrow> </semantics></math>. Here, output of the <math display="inline"><semantics> <mrow> <mi>O</mi> <mi>L</mi> <mi>M</mi> <mn>1</mn> </mrow> </semantics></math> and <math display="inline"><semantics> <mrow> <mi>O</mi> <mi>L</mi> <mi>M</mi> <mn>2</mn> </mrow> </semantics></math> are <math display="inline"><semantics> <mrow> <mi>X</mi> <mo>=</mo> <mi>A</mi> <mo>×</mo> <mi>B</mi> </mrow> </semantics></math> and <math display="inline"><semantics> <mrow> <mi>Y</mi> <mo>=</mo> <mi>C</mi> <mo>×</mo> <mi>D</mi> </mrow> </semantics></math> respectively.</p>
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<p>Processing engine architecture of ECHO. Each PE contains <math display="inline"><semantics> <mrow> <mi>k</mi> <mo>×</mo> <mi>k</mi> </mrow> </semantics></math> multipliers, where each multiplier accepts a bit-serial (input feature) and a parallel (kernel pixel) input.</p>
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<p>Architecture of ECHO for a convolution layer. Each column is equipped with <span class="html-italic">N</span> PEs to facilitate the input channels, while each column of PEs is followed by an online-arithmetic-based reduction tree for the generation of the final SOP. The central controller block generates the termination signals and also controls the dataflow to and from the weight buffers (WBs) and activation buffers (ABs).</p>
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<p>Central controller and decision unit in ECHO.</p>
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<p>Runtimes of the convolution layers for the proposed method with the baseline designs. The proposed design achieved mean runtime improvements of 58.16% and 61.6% compared to conventional bit-serial design (Baseline-1) for VGG-16 and ResNet-18 workloads, respectively.</p>
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<p>Power consumption of the proposed design with the baseline designs. The proposed design achieved <math display="inline"><semantics> <mrow> <mn>81</mn> <mo>%</mo> </mrow> </semantics></math> and <math display="inline"><semantics> <mrow> <mn>82.9</mn> <mo>%</mo> </mrow> </semantics></math> mean reduction in power consumption compared to conventional bit-serial design (Baseline-1) for VGG-16 and ResNet-18 workloads, respectively.</p>
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20 pages, 5994 KiB  
Article
Numerical Analysis of the Stress Shadow Effects in Multistage Hydrofracturing Considering Natural Fracture and Leak-Off Effect
by Jinxin Song, Qing Qiao, Chao Chen, Jiangtao Zheng and Yongliang Wang
Water 2024, 16(9), 1308; https://doi.org/10.3390/w16091308 - 4 May 2024
Cited by 1 | Viewed by 1573
Abstract
As a critical technological approach, multistage fracturing is frequently used to boost gas recovery in compact hydrocarbon reservoirs. Determining an ideal cluster distance that effectively integrates pre-existing natural fractures in the deposit creates a fracture network conducive to gas movement. Fracturing fluid leak-off [...] Read more.
As a critical technological approach, multistage fracturing is frequently used to boost gas recovery in compact hydrocarbon reservoirs. Determining an ideal cluster distance that effectively integrates pre-existing natural fractures in the deposit creates a fracture network conducive to gas movement. Fracturing fluid leak-off also impacts water resources. In our study, we use a versatile finite element–discrete element method that improves the auto-refinement of the grid and the detection of multiple fracture movements to model staged fracturing in naturally fractured reservoirs. This computational model illustrates the interaction between hydraulic fractures and pre-existing fractures and employs the nonlinear Carter leak-off criterion to portray fluid leakage and the impacts of hydromechanical coupling during multistage fracturing. Numerical results show that sequential fracturing exhibits the maximum length in unfractured and naturally fractured models, and the leak-off volume of parallel fracturing is the smallest. Our study proposes an innovative technique for identifying and optimizing the spacing of fracturing clusters in unconventional reservoirs. Full article
(This article belongs to the Special Issue Thermo-Hydro-Mechanical Coupling in Fractured Porous Media)
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<p>Typical uniaxial continuum damage response.</p>
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<p>Communication of network and structure fields during successive coupling time.</p>
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<p>Geometrical models of multistage hydraulic fracturing.</p>
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<p>Multistage fracturing schemes: (<b>a</b>) sequential fracturing; (<b>b</b>) simultaneous fracturing; and (<b>c</b>) parallel fracturing.</p>
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<p>Dynamic propagation of cracks and first principal stress (Pa) in sequential and simultaneous fracturing for different spacings: (<b>a</b>) 12.5 m, (<b>b</b>) 25 m, (<b>c</b>) 50 m, (<b>d</b>) 75 m, and (<b>e</b>) 100 m.</p>
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<p>Dynamic propagation of cracks and shear stress (Pa) in simultaneous fracturing (spacing = 25 m) for different times: (<b>a</b>) t = 22s, (<b>b</b>) t = 1248 s, (<b>c</b>) t = 2077, (<b>d</b>) t = 4539 s, (<b>e</b>) t = 5362 s, and (<b>f</b>) t = 7502 s.</p>
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<p>Dynamic propagation of cracks and first principal stress (Pa) in parallel fracturing for different spacings: (<b>a</b>) 12.5 m, (<b>b</b>) 25 m, (<b>c</b>) 50 m, (<b>d</b>) 75 m, and (<b>e</b>) 100 m.</p>
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<p>Dynamic propagation of cracks and first principal stress (Pa) of sequential and simultaneous fracturing in the naturally fractured model for different spacings: (<b>a</b>) 12.5 m, (<b>b</b>) 25 m, (<b>c</b>) 50 m, (<b>d</b>) 75 m, and (<b>e</b>) 100 m.</p>
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<p>Fracture length of multistage fracturing in the un-fractured and the naturally fractured model at different spacings: (<b>a</b>) un-fractured model and (<b>b</b>) naturally fractured model.</p>
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<p>Evolution of total fracture volume and leak-off volume of different fracturing sequences.</p>
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<p>Evolution of total leak-off volume of different fracturing sequences.</p>
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16 pages, 2237 KiB  
Article
Integrated Approach of Life Cycle Assessment and Experimental Design in the Study of a Model Organic Reaction: New Perspectives in Renewable Vanillin-Derived Chemicals
by Chiara Ruini, Erika Ferrari, Caterina Durante, Giulia Lanciotti, Paolo Neri, Anna Maria Ferrari and Roberto Rosa
Molecules 2024, 29(9), 2132; https://doi.org/10.3390/molecules29092132 - 3 May 2024
Viewed by 1430
Abstract
This work is focused on performing a quantitative assessment of the environmental impacts associated with an organic synthesis reaction, optimized using an experimental design approach. A nucleophilic substitution reaction was selected, employing vanillin as the substrate, a phenolic compound widely used in the [...] Read more.
This work is focused on performing a quantitative assessment of the environmental impacts associated with an organic synthesis reaction, optimized using an experimental design approach. A nucleophilic substitution reaction was selected, employing vanillin as the substrate, a phenolic compound widely used in the food industry and of pharmaceutical interest, considering its antioxidant and antitumoral potential. To carry out the reaction, three different solvents have been chosen, namely acetonitrile (ACN), acetone (Ace), and dimethylformamide (DMF). The syntheses were planned with the aid of a multivariate experimental design to estimate the best reaction conditions, which simultaneously allow a high product yield and a reduced environmental impact as computed by Life Cycle Assessment (LCA) methodology. The experimental results highlighted that the reactions carried out in DMF resulted in higher yields with respect to ACN and Ace; these reactions were also the ones with lower environmental impacts. The multilinear regression models allowed us to identify the optimal experimental conditions able to guarantee the highest reaction yields and lowest environmental impacts for the studied reaction. The identified optimal experimental conditions were also validated by experimentally conducting the reaction in those conditions, which indeed led to the highest yield (i.e., 93%) and the lowest environmental impacts among the performed experiments. This work proposes, for the first time, an integrated approach of DoE and LCA applied to an organic reaction with the aim of considering both conventional metrics, such as reaction yield, and unconventional ones, such as environmental impacts, during its lab-scale optimization. Full article
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<p>Scheme of the investigated reaction: O-alkylation of vanillin with 1-bromobutane.</p>
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<p>Bar diagram plot representing the yield of pure product (3-methoxy-4butoxy-benzaldehyde) in each experiment. Results are grouped according to the used solvent.</p>
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<p>Relative percentage environmental impacts at midpoint level (ReCipe, 2016; H) associated with the production of 1 g of 4-butoxy-3-methoxybenzaldehyde for each of the nineteen reactions, referring to the eighteen impact categories considered.</p>
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<p>Score (<b>a</b>) and loading (<b>b</b>) plots of PCA applied on the LCA midpoint dataset. (<b>c</b>) Zoom-in of the loadings present within the red dashed area of (<b>b</b>).</p>
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<p>Endpoint single score results (ReCiPe, 2016; H, A) for the synthesis of 1 g of 4-butoxy-3-methoxybenzaldehyde for each of the nineteen reactions (R1–R19).</p>
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<p>Surface plots showing the effects of KI and K<sub>2</sub>CO<sub>3</sub> on human health (<b>a</b>), ecosystems (<b>b</b>), and resources (<b>c</b>) responses.</p>
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<p>Flowchart summarizing the system boundaries considered in the LCA analysis.</p>
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13 pages, 2348 KiB  
Article
Computational Approach for Spatially Fractionated Radiation Therapy (SFRT) and Immunological Response in Precision Radiation Therapy
by Paolo Castorina, Filippo Castiglione, Gianluca Ferini, Stefano Forte and Emanuele Martorana
J. Pers. Med. 2024, 14(4), 436; https://doi.org/10.3390/jpm14040436 - 21 Apr 2024
Viewed by 1681
Abstract
The field of precision radiation therapy has seen remarkable advancements in both experimental and computational methods. Recent literature has introduced various approaches such as Spatially Fractionated Radiation Therapy (SFRT). This unconventional treatment, demanding high-precision radiotherapy, has shown promising clinical outcomes. A comprehensive computational [...] Read more.
The field of precision radiation therapy has seen remarkable advancements in both experimental and computational methods. Recent literature has introduced various approaches such as Spatially Fractionated Radiation Therapy (SFRT). This unconventional treatment, demanding high-precision radiotherapy, has shown promising clinical outcomes. A comprehensive computational scheme for SFRT, extrapolated from a case report, is proposed. This framework exhibits exceptional flexibility, accommodating diverse initial conditions (shape, inhomogeneity, etc.) and enabling specific choices for sub-volume selection with administrated higher radiation doses. The approach integrates the standard linear quadratic model and, significantly, considers the activation of the immune system due to radiotherapy. This activation enhances the immune response in comparison to the untreated case. We delve into the distinct roles of the native immune system, immune activation by radiation, and post-radiotherapy immunotherapy, discussing their implications for either complete recovery or disease regrowth. Full article
(This article belongs to the Section Omics/Informatics)
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<p><sup>18</sup>F-FDG PET at different time intervals showing the biggest metastasis located at left axilla: (<b>A</b>) starting condition (<math display="inline"><semantics> <mrow> <mn>171.3</mn> </mrow> </semantics></math> cm<sup>3</sup>); (<b>B</b>) after 1 month and the end of radiotherapy; (<b>C</b>) after 4.5 months and 15 weeks of immunotherapy with cemiplimab (5 intravenous injections).</p>
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<p>Graphical representation of the initial tumor setting. The gross tumor volume (GTV) is divided in three concentric areas: death cells (necrotic), non-proliferating tumor cells (hypoxic) and the cancer cells proliferating zone (oxygenated) with blood vessels.</p>
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<p>CT performed in the last follow-up (November 2023) focused on the axillary zone, the site of a metastasis with size <math display="inline"><semantics> <mrow> <mn>171.3</mn> </mrow> </semantics></math> cm<sup>3</sup> (April 2021), shows no cancer recurrence. The patient was still under immunotherapy.</p>
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<p>Normoxic volume progression. Red curve: LQM calculation with endpoint at <math display="inline"><semantics> <mrow> <mn>0.009</mn> </mrow> </semantics></math> cm<sup>3</sup>. Black square: experimental tumor size at the end of radiotherapy (assumed <math display="inline"><semantics> <mrow> <mn>0.006</mn> </mrow> </semantics></math> cm<sup>3</sup>). Black curve: tumor regrowth with induced immune response, <math display="inline"><semantics> <mrow> <mi>A</mi> <mo>(</mo> <mn>0</mn> <mo>,</mo> <mn>10</mn> <mo>)</mo> <mo>=</mo> <mn>0.4</mn> </mrow> </semantics></math> and no immunotherapy. Blue curve: tumor regrowth with <math display="inline"><semantics> <mrow> <mi>A</mi> <mo>(</mo> <mn>0</mn> <mo>,</mo> <mn>10</mn> <mo>)</mo> </mrow> </semantics></math> plus a slow increasing immunotherapy <span class="html-italic">B</span>(<span class="html-italic">t</span>,11) = 0.05 <span class="html-italic">ln</span> (<span class="html-italic">t</span>/11). Green curve: complete recovery due to <math display="inline"><semantics> <mrow> <mi>A</mi> <mo>(</mo> <mn>0</mn> <mo>,</mo> <mn>10</mn> <mo>)</mo> </mrow> </semantics></math> plus a constant <math display="inline"><semantics> <mrow> <mi>I</mi> <mo>(</mo> <mi>t</mi> <mo>)</mo> </mrow> </semantics></math> which gives a linear increase with time of the cumulated effect <span class="html-italic">B</span>(<span class="html-italic">t</span>,11) = 0.05 (<span class="html-italic">t</span>− 11). <span class="html-italic">t</span> in day.</p>
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19 pages, 8388 KiB  
Article
CFD−DEM Simulation of a Jamming Mechanism and Influencing Factors of a Fracture-Shrinking Model
by Jiabin Zhang, Cong Lu, Tao Zhang and Jianchun Guo
Processes 2024, 12(4), 822; https://doi.org/10.3390/pr12040822 - 18 Apr 2024
Viewed by 941
Abstract
Fractured-vuggy reservoirs are crucial for increasing unconventional oil storage and production, but the controlling mechanism of this dominant flow channel remains vague, and the jamming mechanism of modulator particles is unclear. This study explores the filling and jamming processes of particles in the [...] Read more.
Fractured-vuggy reservoirs are crucial for increasing unconventional oil storage and production, but the controlling mechanism of this dominant flow channel remains vague, and the jamming mechanism of modulator particles is unclear. This study explores the filling and jamming processes of particles in the fractures by conducting a computational fluid dynamics−discrete element method (CFD−DEM) coupled simulation, considering the variation of fracture width, fluid velocity, particle size, and concentration. Results suggest that four sealing modes are proposed: normal filling, local jamming, complete sealing, and sealing in the main fracture. The ratio of particle size to the main fracture width exerts the primary role, with the ratio having a range of 0.625 < D/W ≤ 0.77 revealing complete jamming. Furthermore, an optimal particle size for achieving stable sealing is observed when the particle size varies from 2 to 2.5 mm. A higher concentration of particles yields better results in the fracture-shrinking model. Conversely, a greater velocity worsens the sealing effect on fractures. This research can offer technical support for the large-scale dissemination of flow regulation technology. Full article
(This article belongs to the Special Issue Advanced Fracturing Technology for Oil and Gas Reservoir Stimulation)
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<p>Geometry of the fracture-shrinking model.</p>
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<p>Comparison and validation of numerical simulation (<b>a</b>) and physical experiment (<b>b</b>).</p>
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<p>Filling process of sealing mode 1.</p>
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<p>Significant pressure drop caused by accumulation of particles. (<b>a</b>) Fluid pressure drop in the fracture, (<b>b</b>) pressure curve along the middle section of the model (sealing mode 1).</p>
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<p>Accumulating and jamming process of sealing mode 2.</p>
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<p>Pressure distribution due to the accumulation of particles. (<b>a</b>) Fluid pressure drop in the fracture, (<b>b</b>) pressure curve along the middle section of the model (sealing mode 2).</p>
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<p>Accumulating and jamming process of the model.</p>
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<p>Pressure distribution due to the accumulation of particles. (<b>a</b>) Fluid pressure drop in the fracture, (<b>b</b>) pressure curve along the middle section of the model (sealing mode 3).</p>
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<p>Accumulating and local jamming in the main fracture.</p>
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<p>Pressure distribution due to the accumulation of particles. (<b>a</b>) Fluid pressure drop in the fracture, (<b>b</b>) pressure curve along the middle section of the model (sealing mode 4).</p>
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<p>Local microscopic views of four modes of sealing.</p>
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<p>Jamming mechanisms corresponding to different D/W. Blue line is the connection between particles while the different colors of particle mean the locations of particles.</p>
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<p>Jamming morphology with different particle sizes.</p>
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<p>Local stuck morphology under different particle sizes.</p>
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<p>Fluid pressure drop in the fracture with different particle sizes.</p>
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<p>Blocking effect of modulator particles under different concentration conditions (Group 1).</p>
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<p>Pressure drop distribution under different concentration conditions.</p>
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<p>Sealing effect of flow regulator particles at different volume concentrations (Group 2).</p>
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<p>Schematic diagram of particle arrangement under different concentration conditions.</p>
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<p>Sealing effect of flow regulator particles under different injection velocities (Group 1).</p>
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<p>Sealing effect of flow regulator particles at different pumping velocities (Group 2).</p>
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<p>Variations in particle motion related to different concentration conditions. Arrows are the moving direction for flows.</p>
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23 pages, 3974 KiB  
Article
Approaches of Combining Machine Learning with NMR-Based Pore Structure Characterization for Reservoir Evaluation
by Wenjun Zhao, Tangyan Liu, Jian Yang, Zhuo Zhang, Cheng Feng and Jizhou Tang
Sustainability 2024, 16(7), 2774; https://doi.org/10.3390/su16072774 - 27 Mar 2024
Cited by 2 | Viewed by 1069
Abstract
Tight gas, a category of unconventional natural gas, relies on advanced intelligent monitoring methods for their extraction. Conventional logging for reservoir evaluation relies on logging data and the manual setting of evaluation criteria to classify reservoirs. However, the complexity and heterogeneity of tight [...] Read more.
Tight gas, a category of unconventional natural gas, relies on advanced intelligent monitoring methods for their extraction. Conventional logging for reservoir evaluation relies on logging data and the manual setting of evaluation criteria to classify reservoirs. However, the complexity and heterogeneity of tight reservoirs pose challenges in accurately identifying target layers by using traditional well-logging techniques. Machine learning may hold the key to solving this problem, as it enables computers to learn without being explicitly programmed and manually adding rules. Therefore, it is possible to make reservoir evaluations using machine learning methods. In this paper, the reservoir quality index (RQI) and porous geometric parameters obtained from the optimized inversion of the spherical–tubular model are adopted to evaluate the reservoir. Then, three different machine learning approaches, the random forest (RF) algorithm, support vector machine (SVM) algorithm, and extreme gradient boosting (XGB) algorithm, are utilized for reservoir classification. The selected dataset covers more than 7000 samples from five wells. The data from four wells are arranged as the training dataset, and the data of the remaining one well is designed as the testing dataset to calculate the prediction accuracies of different machine learning algorithms. Among them, accuracies of RF, SVM, and XGB are all higher than 90%, and XGB owns the highest result by reaching 97%. Machine learning based approaches can greatly assist reservoir prediction by implementing the well-logging data. The research highlights the application of reservoir classification with a higher prediction accuracy by combining machine learning algorithms with NMR-logging-based pore structure characterization, which can provide a guideline for sweet spot identification within the tight formation. This not only optimizes resource extraction but also aligns with the global shift towards clean and renewable energy sources, promoting sustainability and reducing the carbon footprint associated with conventional energy production. In summary, the fusion of machine learning and NMR-logging-based reservoir evaluation plays a crucial role in advancing both energy efficiency and the transition to cleaner energy sources. Full article
(This article belongs to the Section Energy Sustainability)
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<p>Schematic of the workflow presented in this work.</p>
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<p>Schematic diagram of the RF.</p>
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<p>Application diagram of RF.</p>
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<p>Schematic diagram of the SVM.</p>
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<p>Application diagram of SVM.</p>
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<p>Schematic diagram of the XGB.</p>
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<p>Application diagram of XGB.</p>
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<p>Simulation and parameter description of the spherical–tubular model.</p>
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<p>Analyses of reservoir porosity and permeability characteristics.</p>
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<p>Correlation analysis diagram.</p>
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<p>Confusion matrix and accuracy graph. (<b>a</b>) Prediction of confusion matrix by RF; (<b>b</b>) Prediction of confusion matrix by SVM; (<b>c</b>) Prediction of confusion matrix by XGB; (<b>d</b>) Different algorithm accuracy graph.</p>
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<p>Prediction results of different prediction models for different reservoirs.</p>
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<p>Predicted results of the well-log plot.</p>
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32 pages, 10632 KiB  
Review
Proto-Neurons from Abiotic Polypeptides
by Panagiotis Mougkogiannis and Andrew Adamatzky
Encyclopedia 2024, 4(1), 512-543; https://doi.org/10.3390/encyclopedia4010034 - 8 Mar 2024
Cited by 2 | Viewed by 1857
Abstract
To understand the origins of life, we must first gain a grasp of the unresolved emergence of the first informational polymers and cell-like assemblies that developed into living systems. Heating amino acid mixtures to their boiling point produces thermal proteins that self-assemble into [...] Read more.
To understand the origins of life, we must first gain a grasp of the unresolved emergence of the first informational polymers and cell-like assemblies that developed into living systems. Heating amino acid mixtures to their boiling point produces thermal proteins that self-assemble into membrane-bound protocells, offering a compelling abiogenic route for forming polypeptides. Recent research has revealed the presence of electrical excitability and signal processing capacities in proteinoids, indicating the possibility of primitive cognitive functions and problem-solving capabilities. This review examines the characteristics exhibited by proteinoids, including electrical activity and self-assembly properties, exploring the possible roles of such polypeptides under prebiotic conditions in the emergence of early biomolecular complexity. Experiments showcasing the possibility of unconventional computing with proteinoids as well as modelling proteinoid assemblies into synthetic proto-brains are given. Proteinoids’ robust abiogenic production, biomimetic features, and computational capability shed light on potential phases in the evolution of polypeptides and primitive life from the primordial environment. Full article
(This article belongs to the Section Biology & Life Sciences)
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<p>Molecular model of an 11-residue thermal proteinoids peptide chain containing alternating glutamic acid and arginine units. Each glutamic acid (L-Glu) aspartic acid (L-Asp) and phenylalanine (L-Phe) monomer is depicted in ball-and-stick representation with nitrogen atoms colored blue, oxygen red, carbon dark grey, and hydrogen light grey. The polypeptide backbone illustrates structure formed through thermal condensation polymerisation which can further self-assemble into higher-order proteinoid microspheres. The proteinoid structure was generated using ChimeraX molecular visualisation software.</p>
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<p>The mechanism underlying the aggregation of proteinoids. Proteinoids have the inherent ability to undergo self-assembly and disintegration processes, resulting in the formation of complex molecular structures like microspheres. This process is facilitated through the presence of hydrophobic interactions and hydrogen bonding between proteinoid branches, which bears a resemblance to the biological processes of protein folding and aggregation. Proteinoid aggregates exhibit a perpetual influx and efflux of material, hence sustaining an internal state characterised by constant change. Various environmental conditions, including temperature, pH, and ionic strength, have the ability to influence the equilibrium towards specific aggregated states [<a href="#B126-encyclopedia-04-00034" class="html-bibr">126</a>].</p>
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<p>(<b>a</b>,<b>b</b>) Perfect proteinoid microspheres self-assembled from a supersaturated precursor solution. Microspheres have a diameter of 1.2 microns. Magnification 60,000×, scale bar 500 nm. (<b>c</b>) Cubic crystal with a central cavity formed after applying an electrical voltage to proteinoids. The cubic morphology suggests reorganisation of proteinoids under electrical stimuli. Magnification 8000×, scale bar 5 μm. (<b>d</b>) Nanoscale proteinoid spheres arranged on the surface of a cubic crystal substrate. This highlights preferential interactions between proteinoids and crystal surfaces. Magnification 40,000×, scale bar 1 μm.</p>
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<p>Memfractance current–voltage characteristics of L-Glu:L-Arg proteinoids. The I–V curve shows the nonlinear memfractance behavior, with currents of −3.95 μA at −1 V and 3.57 μA at +1 V. Hysteresis is observed around 0 V, with currents of −0.6898 μA when sweeping from high to low voltages and 0.9043 μA when sweeping low to high. The asymmetric I-V response demonstrates that proteinoids can exhibit memristive-like electrical properties that may be harnessed for bioelectronic applications. Further tuning the composition and assembly conditions enables engineering proteinoids as adaptive, multifunctional electronic materials.</p>
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<p>Memfractance of L-Glu:L-Arg proteinoid gel in hydroxyapatite (HAP). The I–V characteristics were measured with the proteinoid gel immersed in 200 mL HAP solution at pH 7.4, 0.15 M ionic strength, and 37 °C. The HAP environment enhances memfractance, with currents of −77.4 μA at −1 V and 79.788 μA at +1 V. The near-zero current of −0.494 μA at 0 V indicates reduced hysteresis. Incorporating biomimetic minerals thus tunes proteinoids’ memfractance performance.</p>
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<p>Amino acids undergo thermal polymerisation resulting in proteinoids. By means of intramolecular cyclisation and condensation reactions, heating glutamic acid, aspartic acid, and lysine produces pyroglutamic acid, cyclic diaspartic acid, and caprolactam, respectively (<b>top</b>). Cyclic amino acid derivatives have the ability to undergo additional polymerisation, resulting in the formation of proteinoid microsphere chains (see (<b>bottom</b>)). The figure depicts the standard chemical reactions that occur during the synthesis of proteinoids from amino acid precursors. By manipulating the monomer composition and heating conditions, it is possible to produce proteinoids with specific properties under control [<a href="#B187-encyclopedia-04-00034" class="html-bibr">187</a>].</p>
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<p>Long-term electrical activity in proteinoids microspheres. Voltage recording over 21 h exhibits characteristic spiking patterns, with magnified inserts showing details of spikes over time. The continued signaling demonstrates sustained excitability arising from the proteinoids’ self-assembly.</p>
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<p>A typical spike in proteinoids electrical potential. The spike displays rapid depolarisation and repolarisation phases. This transient electrical event results from electrostatic interactions between proteinoid dipoles, which produce propagation of excitation through the microsphere network. The spike shape shows proteinoids can mimic key features of neural action potentials.</p>
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<p>Onion-like proteinoid–CAP nanostructures. This is a scanning electron micrograph that displays proteinoids arranged in many layers around a carbonate apatite (CAP) core. The proteinoids are templated on HAP substrates. The onion-like structure is formed due to the selective aggregation of proteinoids around the mineral particles during nucleation. The scale bar is 500 nanometers. The magnification is 60,000 times. The spot size is 2.0 and the accelerating voltage is 2.0 kilovolts.</p>
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<p>The PSI and PPI values of several proteinoids are shown in the colour map. The postsynaptic index, or PSI, measures the strength of interneuronal connections in a network, either chemically or functionally. For post-postsynaptic index, see PPI. It measures how effective interneuronal connections are within a certain network. Lighter shades of yellow imply higher PPI values, while darker shades of blue suggest higher PSI values. The relationship between postsynaptic and presynaptic neurons and how they affect proteinoid function is depicted in the map.</p>
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