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Search Results (8,837)

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16 pages, 1722 KiB  
Article
Full-Length Transcriptomes Reconstruction Reveals Intraspecific Diversity in Hairy Vetch (Vicia villosa Roth) and Smooth Vetch (V. villosa Roth var. glabrescens)
by Weiyi Kong, Bohao Geng, Wenhui Yan, Jun Xia, Wenkai Xu, Na Zhao and Zhenfei Guo
Plants 2024, 13(23), 3291; https://doi.org/10.3390/plants13233291 - 22 Nov 2024
Abstract
Hairy vetch (Vicia villosa Roth) and smooth vetch (V. villosa Roth var. glabrescens) are important cover crops and legume forage with great economic and ecological values. Due to the large and highly heterozygous genome, full-length transcriptome reconstruction is a cost-effective [...] Read more.
Hairy vetch (Vicia villosa Roth) and smooth vetch (V. villosa Roth var. glabrescens) are important cover crops and legume forage with great economic and ecological values. Due to the large and highly heterozygous genome, full-length transcriptome reconstruction is a cost-effective route to mining their genetic resources. In this study, a hybrid sequencing approach combining SMRT and NGS technologies was applied. The results showed that 28,747 and 40,600 high-quality non-redundant transcripts with an average length of 1808 bp and 1768 bp were generated from hairy vetch and smooth vetch, including 24,864 and 35,035 open reading frames (ORFs), respectively. More than 96% of transcripts were annotated to the public databases, and around 25% of isoforms underwent alternative splicing (AS) events. In addition, 987 and 1587 high-confidence lncRNAs were identified in two vetches. Interestingly, smooth vetch contains more specific transcripts and orthologous clusters than hairy vetch, revealing intraspecific transcript diversity. The phylogeny revealed that they were clustered together and closely related to the genus Pisum. Furthermore, the estimation of Ka/Ks ratios showed that purifying selection was the predominant force. A putative 3-dehydroquinate dehydratase/shikimate dehydrogenase (DHD/SDH) gene underwent strong positive selection and might regulate phenotypic differences between hairy vetch and smooth vetch. Overall, our study provides a vital characterization of two full-length transcriptomes in Vicia villosa, which will be valuable for their molecular research and breeding. Full article
(This article belongs to the Special Issue Genetic and Biological Diversity of Plants)
15 pages, 355 KiB  
Article
Statistical Modeling to Improve Time Series Forecasting Using Machine Learning, Time Series, and Hybrid Models: A Case Study of Bitcoin Price Forecasting
by Moiz Qureshi, Hasnain Iftikhar, Paulo Canas Rodrigues, Mohd Ziaur Rehman and S. A. Atif Salar
Mathematics 2024, 12(23), 3666; https://doi.org/10.3390/math12233666 - 22 Nov 2024
Abstract
Bitcoin (BTC-USD) is a virtual currency that has grown in popularity after its inception in 2008. BTC-USD is an internet communication network that makes using digital money, including digital payments, easy. It offers decentralized clearing of transactions and money supply. This study attempts [...] Read more.
Bitcoin (BTC-USD) is a virtual currency that has grown in popularity after its inception in 2008. BTC-USD is an internet communication network that makes using digital money, including digital payments, easy. It offers decentralized clearing of transactions and money supply. This study attempts to accurately anticipate the BTC-USD prices (Close) using data from September 2023 to September 2024, comprising 390 observations. Four machine learning models—Multi-layer Perceptron, Extreme Learning Machine, Neural Network AutoRegression, and Extreme-Gradient Boost—as well as four time series models—Auto-Regressive Integrated Moving Average, Auto-Regressive, Non-Parametric Auto-Regressive, and Simple Exponential Smoothing models—are used to achieve this end. Various hybrid models are then proposed utilizing these models, which are based on simple averaging of these models. The data-splitting technique, commonly used in comparative analysis, splits the data into training and testing data sets. Through comparison testing with training data sets consisting of 30%, 20%, and 10%, the present work demonstrated that the suggested hybrid model outperforms the individual approaches in terms of error metrics, such as the MAE, RMSE, MAPE, SMAPE, and direction accuracy, such as correlation and the MDA of BTC. Furthermore, the DM test is utilized in this study to measure the differences in model performance, and a graphical evaluation of the models is also provided. The practical implication of this study is that financial analysts have a tool (the proposed model) that can yield insightful information about potential investments. Full article
(This article belongs to the Special Issue Time Series Forecasting for Economic and Financial Phenomena)
18 pages, 850 KiB  
Article
A Hybrid Quantum Solver for the Lorenz System
by Sajad Fathi Hafshejani, Daya Gaur, Arundhati Dasgupta, Robert Benkoczi, Narasimha Reddy Gosala and Alfredo Iorio
Entropy 2024, 26(12), 1009; https://doi.org/10.3390/e26121009 - 22 Nov 2024
Abstract
We develop a hybrid classical–quantum method for solving the Lorenz system. We use the forward Euler method to discretize the system in time, transforming it into a system of equations. This set of equations is solved by using the Variational Quantum Linear Solver [...] Read more.
We develop a hybrid classical–quantum method for solving the Lorenz system. We use the forward Euler method to discretize the system in time, transforming it into a system of equations. This set of equations is solved by using the Variational Quantum Linear Solver (VQLS) algorithm. We present numerical results comparing the hybrid method with the classical approach for solving the Lorenz system. The simulation results demonstrate that the VQLS method can effectively compute solutions comparable to classical methods. The method is easily extended to solving similar nonlinear differential equations. Full article
(This article belongs to the Special Issue Quantum Computing for Complex Dynamics, 2nd Edition)
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Figure 1

Figure 1
<p>The trajectory was generated by using the method described in <a href="#sec2dot2-entropy-26-01009" class="html-sec">Section 2.2</a> on a classical computer. (<b>a</b>) The starting point is <math display="inline"><semantics> <mrow> <mo>(</mo> <mn>1</mn> <mo>,</mo> <mn>2</mn> <mo>,</mo> <mo>−</mo> <mn>4</mn> <mo>)</mo> </mrow> </semantics></math>. (<b>b</b>) The starting point is <math display="inline"><semantics> <mrow> <mo>(</mo> <mn>30</mn> <mo>,</mo> <mo>−</mo> <mn>40</mn> <mo>,</mo> <mn>10</mn> <mo>)</mo> </mrow> </semantics></math>.</p>
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<p>Blue: the starting point is <math display="inline"><semantics> <mrow> <mo>(</mo> <mn>1</mn> <mo>×</mo> <msup> <mn>10</mn> <mrow> <mo>−</mo> <mn>16</mn> </mrow> </msup> <mo>,</mo> <mn>1</mn> <mo>×</mo> <msup> <mn>10</mn> <mrow> <mo>−</mo> <mn>16</mn> </mrow> </msup> <mo>,</mo> <mn>1</mn> <mo>×</mo> <msup> <mn>10</mn> <mrow> <mo>−</mo> <mn>16</mn> </mrow> </msup> <mo>)</mo> </mrow> </semantics></math>. Red: the starting point is <math display="inline"><semantics> <mrow> <mo>(</mo> <mn>1</mn> <mo>×</mo> <msup> <mn>10</mn> <mrow> <mo>−</mo> <mn>16</mn> </mrow> </msup> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mo>−</mo> <mn>1</mn> <mo>×</mo> <msup> <mn>10</mn> <mrow> <mo>−</mo> <mn>16</mn> </mrow> </msup> <mo>,</mo> <mn>1</mn> <mo>×</mo> <msup> <mn>10</mn> <mrow> <mo>−</mo> <mn>16</mn> </mrow> </msup> <mrow> <mo>)</mo> </mrow> </mrow> </semantics></math>, and the parameters are <math display="inline"><semantics> <mrow> <mo>(</mo> <mn>13.92655741</mn> <mo>,</mo> <mn>10</mn> <mo>,</mo> <mn>2.667</mn> <mo>)</mo> </mrow> </semantics></math>. The two trajectories generated by using the method in <a href="#sec2dot2-entropy-26-01009" class="html-sec">Section 2.2</a> differ widely.</p>
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<p>The starting point is <math display="inline"><semantics> <mrow> <mo>(</mo> <mn>1</mn> <mo>,</mo> <mn>1</mn> <mo>,</mo> <mn>1</mn> <mo>)</mo> </mrow> </semantics></math>.</p>
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<p>Five-layer Ansatz used in the VQLS algorithm.</p>
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<p>The expectation value as a function of the number of layers.</p>
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<p>The relationship between the condition number of matrix <span class="html-italic">A</span> and the value of <span class="html-italic">h</span>.</p>
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<p>The relative error of the quantum and classical methods for 500 iterations with a step size of 0.001. The average error is an order of magnitude larger than the step size.</p>
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<p>Trajectories computed by using classical and quantum methods. (<b>a</b>) Comparison of classical and quantum results for the first 2000 iterations. (<b>b</b>) Trajectories computed by classical and quantum simulations. The initial point is (<math display="inline"><semantics> <mrow> <mn>1</mn> <mo>×</mo> <msup> <mn>10</mn> <mrow> <mo>−</mo> <mn>16</mn> </mrow> </msup> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mo>−</mo> <mn>1</mn> <mo>×</mo> <msup> <mn>10</mn> <mrow> <mo>−</mo> <mn>16</mn> </mrow> </msup> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mn>1</mn> <mo>×</mo> <msup> <mn>10</mn> <mrow> <mo>−</mo> <mn>16</mn> </mrow> </msup> </mrow> </semantics></math>), and 10,000 timesteps are shown. The same attractor is discovered by both methods.</p>
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<p>The error for classical computation as given by Equation (<a href="#FD34-entropy-26-01009" class="html-disp-formula">34</a>). (<b>a</b>) The error for the trajectory computed in <a href="#entropy-26-01009-f001" class="html-fig">Figure 1</a>. (<b>b</b>) The error for the trajectory computed in <a href="#entropy-26-01009-f002" class="html-fig">Figure 2</a>.</p>
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<p>Classical error vs. quantum error. (<b>a</b>) Errors for the trajectories computed in <a href="#entropy-26-01009-f008" class="html-fig">Figure 8</a>a. (<b>b</b>) The error for the trajectory computed in <a href="#entropy-26-01009-f008" class="html-fig">Figure 8</a>b.</p>
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12 pages, 1614 KiB  
Systematic Review
Diagnostic Value of Nuclear Hybrid Imaging in Malignant Struma Ovarii: A Systematic Review of Case Reports
by Claudiu Peștean and Doina Piciu
Diagnostics 2024, 14(23), 2630; https://doi.org/10.3390/diagnostics14232630 - 22 Nov 2024
Abstract
Background: Struma ovarii is a rare tumor, a type of ovarian mature teratoma consisting over 50% of its mass in thyroid ectopic tissue; 5% to 10% of cases, as described in the literature, are malignant and well known as malignant struma ovarii or [...] Read more.
Background: Struma ovarii is a rare tumor, a type of ovarian mature teratoma consisting over 50% of its mass in thyroid ectopic tissue; 5% to 10% of cases, as described in the literature, are malignant and well known as malignant struma ovarii or thyroid cancer from struma ovarii. Due to the limited number of malignant struma ovarii cases, the diagnostic and therapeutic approach of malignant struma ovarii lacks in standardization. Methods: We performed a comprehensive search on the English language PubMed and Google Scholar. We used specific controlled keywords “PET CT”, “SPECT CT”, “PET MRI”, “malignant struma ovarii”, “hybrid imaging” and “mature ovarian teratoma”. Upon the retrieval of potential articles, we analyzed them for their eligibility. The inclusion criteria were: articles discussing the role of PET/CT and SPECT/CT hybrid imaging in malignant struma ovarii, full-text articles on the topic of interest and English publications. The exclusion criteria were articles not directly related to the hybrid imaging and not discussing the subject of malignant struma ovarii. Results: A total of 64 articles were screened, 35 duplicates were eliminated, 15 articles excluded and a total number of 14 articles were included for this systematic review, 13 of them being case reports and one being a case report with a systematic review. F-18 FDG PET/CT contributed in seven cases (50%), I-131 NaI SPECT/CT in seven cases (50%) and I-124 NaI PET/CT in two cases (14.29%). In two cases, 131 NaI SPECT/CT and F-18 FDG PET/CT were used as complementary investigation tools. The hybrid imaging methods used as a part of the diagnostic strategy were accompanied by several diagnostic alternatives: ultrasounds, CT, MRI, I-131 NaI WBS and I-123 NaI WBS. Conclusions: There is no consistent or standardized diagnostic and therapeutic approach for malignant struma ovarii. Hybrid imaging methods may be of great value in initial diagnostic and the association of F-18 FDG PET/CT and I-131 NaI SPECT/CT is a successful diagnostic approach. The association of hybrid imaging with other diagnostic imaging alternatives in initial diagnostic and follow up is essential. Full article
(This article belongs to the Special Issue An Update on Radiological Diagnosis in 2024)
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<p>Selection criteria (PRISMA flow diagram).</p>
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<p>The histology of malignant struma ovarii (FVPTC—follicular variant of papillary thyroid carcinoma; PTC—papillary thyroid carcinoma; FTC—follicular thyroid carcinoma).</p>
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<p>The localization metastases from malignant struma ovarii.</p>
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<p>The contribution of hybrid imaging methods to the diagnostic strategy for malignant struma ovarii (I-131 NaI SPECT/CT—I-131 (natrium iodine) radioiodine single photon emission tomography fused with computer tomography; F-18 FDG PET/CT F-18 fluorine fluoro-deoxi-glucose positron emission tomography fused with computer tomography; I-124 NaI PET/CT—I-124 (natrium iodine) radioiodine positron emission tomography fused with computer tomography).</p>
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<p>The diagnostic methods used with hybrid imaging tools for malignant struma ovarii (I-131 NaI WBS—I-131 (natrium iodine) radioiodine whole body scan; CT—computer tomography; US—ultrasound; MRI—magnetic resonance imaging; I-123 NaI WBS—I-123 (natrium iodine) radioiodine whole body scan).</p>
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16 pages, 5987 KiB  
Article
From Single Shot to Structure: End-to-End Network-Based Deflectometry for Specular Free-Form Surface Reconstruction
by M.Hadi Sepanj, Saed Moradi, Amir Nazemi, Claire Preston, Anthony M. D. Lee and Paul Fieguth
Appl. Sci. 2024, 14(23), 10824; https://doi.org/10.3390/app142310824 - 22 Nov 2024
Abstract
Deflectometry is a key component in the precise measurement of specular (mirrored) surfaces; however, traditional methods often lack an end-to-end approach that performs 3D reconstruction in a single shot with high accuracy and generalizes across different free-form surfaces. This paper introduces a novel [...] Read more.
Deflectometry is a key component in the precise measurement of specular (mirrored) surfaces; however, traditional methods often lack an end-to-end approach that performs 3D reconstruction in a single shot with high accuracy and generalizes across different free-form surfaces. This paper introduces a novel deep neural network (DNN)-based approach for end-to-end 3D reconstruction of free-form specular surfaces using single-shot deflectometry. Our proposed network, VUDNet, innovatively combines discriminative and generative components to accurately interpret orthogonal fringe patterns and generate high-fidelity 3D surface reconstructions. By leveraging a hybrid architecture integrating a Variational Autoencoder (VAE) and a modified U-Net, VUDNet excels in both depth estimation and detail refinement, achieving superior performance in challenging environments. Extensive data simulation using Blender leading to a dataset which we will make available, ensures robust training and enables the network to generalize across diverse scenarios. Experimental results demonstrate the strong performance of VUDNet, setting a new standard for 3D surface reconstruction. Full article
(This article belongs to the Special Issue Technical Advances in 3D Reconstruction)
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<p>Overview of the context faced by this paper: A known fringe pattern is reflected by some shape of interest, and the resulting reflection is captured by a camera. Our proposed method, VUDNet, reconstructs the estimated shape based on the observed image, trained on a dataset of simulated reflections.</p>
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<p>General architecture of the proposed VUDNet for end-to-end 3D reconstruction of specular free-form surfaces. The network integrates a Variational Autoencoder (VAE, <b>bottom</b>) for coarse depth estimation and a modified U-Net (<b>top</b>) for detail refinement. The ensemble approach leverages both generative and discriminative components, combining their outputs (<b>right</b>) to produce accurate depth maps from single-shot 2D images.</p>
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<p>Simulation environment setup for generating the dataset. The environment includes a fixed camera, a fixed pattern, and various surface settings to replicate realistic deflectometry scenarios. An orthogonal sinusoidal fringe pattern is projected onto specular objects, and the reflected fringes are captured by the camera. This setup ensures the generation of a robust and varied dataset, essential for training the VUDNet to accurately reconstruct 3D surfaces from single-shot 2D images. Since this image is a direct screenshot from the Blender environment, the surface is reflecting the simulated world background. The reflection of the pattern plane on the surface is visible to the camera.</p>
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<p>Mean absolute difference between the ground truth depth map and the predicted depth map from our VUDNet model for a selected sample. The error pattern demonstrates smoothness, effective regularization, and an overall minimal presence of outliers. The top region contains localized patterns of higher error values (illustrated as collection of red pixels), however despite these localized artifacts, the remainder of the image demonstrates the model’s accuracy with no visible orthogonal fringe patterns.</p>
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<p>Comparison of ground truth (<b>left</b>) and VUDNet-estimated depth maps (<b>right</b>), showing effective noise reduction and fine detail retention. The top images showcase a result for a deformation sample, while the bottom images represent an example of the geometric case.</p>
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<p>VAE representation (<b>left</b>) showcasing distinct separation of clusters in the latent space, visualized as the first and second components of t-SNE. The clustering indicates effective differentiation of surface characteristics and potent feature extraction. The four images on the right correspond to the selected points in the latent space (<b>right</b>). It is evident that images from a given cluster share related surface characteristics, highlighting the network’s ability to identify underlying similarities despite variations in surface characteristics.</p>
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<p>The image panels here are organized the same as in <a href="#applsci-14-10824-f006" class="html-fig">Figure 6</a>, with the latent space (<b>left</b>) visualized from the first and second components of t-SNE, and the images (<b>right</b>) corresponding to the selected points in the latent space. The difference is that <a href="#applsci-14-10824-f006" class="html-fig">Figure 6</a> was trained on the entire dataset, whereas here it is trained exclusively on the deformation data. It is clear that images positioned closer in the latent space share more similarities in reflection shape, while those farther apart are less similar, even though they belong to the same overall category of deformation surfaces. This emphasizes the network’s capability to capture underlying similarities despite variations in surface characteristics within the same category.</p>
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14 pages, 4458 KiB  
Article
Development of Conductive Antibacterial Coatings on Cotton Fabrics via Polyphenol-Mediated Silver Mirror Reaction
by Yixiao Wu, Chenlin Fu, Jiaxin Xin, Lin Yang, Chong Zhao and Kun Yan
Polymers 2024, 16(23), 3244; https://doi.org/10.3390/polym16233244 - 22 Nov 2024
Abstract
Herein, this study reports the development of a multifunctional conductive antibacterial cotton fabric through the utilization of the natural polyphenol-mediated silver mirror reaction. The experimental results demonstrate that polyphenols can effectively facilitate the deposition of silver nanoparticles (AgNPs), resulting in a uniform and [...] Read more.
Herein, this study reports the development of a multifunctional conductive antibacterial cotton fabric through the utilization of the natural polyphenol-mediated silver mirror reaction. The experimental results demonstrate that polyphenols can effectively facilitate the deposition of silver nanoparticles (AgNPs), resulting in a uniform and durable hybrid nanocoating on the cotton fabric. The effects of polyphenol’s molecular weights on the coating structures and stabilities have been revealed via two distinct approaches: washing resistance and electrochemical testing systems. It has been concluded that lower-molecular-weight phenols induce a compact and dense coating structure, whereas polyphenols such as tannic acid exhibit relatively high stability, achieving an excellent conductivity of 0.2 S/cm and a good washing resistance of 67% over five cycles. The underlying mechanism has been further confirmed by the cyclic voltammetry measurements, suggesting that polyphenols play a significant role in stabilizing AgNPs and preventing their dissolution. Furthermore, the Ag-doped polyphenol-coated fabrics exhibit notable antibacterial properties. By coupling natural polyphenols with typical silver mirror reactions, this study not only offers a sustainable alternative to synthetic chemicals but also presents a promising method to endow cotton textiles with the dual properties of conductivity and antibacterial activity. Full article
(This article belongs to the Special Issue Biomaterials Modification, Characterization and Applications)
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<p>(<b>a</b>) The chemical structures of natural polyphenols and the effects of their molecular weights on the structures of polyphenol@Ag nanocoatings. (<b>b</b>) The schematic illustrates the preparation processes and polyphenol-mediated self-assembly of AgNPs on the cotton fabric.</p>
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<p>(<b>a</b>) Optical and SEM images of the cotton fabrics before and after modification with different natural polyphenols and AgNPs. (<b>b</b>) The schematic illustrates the possible structures of nanocoatings prepared from natural polyphenols with different molecular weights.</p>
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<p>(<b>a</b>) Optical images, (<b>b</b>) water contact angles, (<b>c</b>) crystalline structures (XRD), and (<b>d</b>) mechanical properties of the cotton fabrics decorated with different components.</p>
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<p>(<b>a</b>) Photothermal images of the as-prepared fabrics irradiated with an infrared (IR) lamp for 5 min; the power density is about 0.5 W cm<sup>−2</sup>. (<b>b</b>) The surface temperature as a function of irradiation time and the compositions of the fabrics. (<b>c</b>) Photo-heating rates of the fabrics with different nanocoating treatments.</p>
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<p>(<b>a</b>) Conductivities of the fabrics before and after being washed in water at 60 °C for five cycles (each cycle lasting about 1 min, stirring speed: 1500 r/min). (<b>b</b>) Assessment of the stability of the fabric’s conductivity after five rounds of washing; the inserted images indicate the high conductivity that allowed the fabric to light up a LED light. (<b>c</b>) Surface morphologies of the fabrics before and after washing treatments.</p>
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<p>(<b>a</b>) The cyclic voltammetry (CV) measurements were conducted using conductive fabrics as the working electrodes in a distilled water (DI) solution (20 mV/s). (<b>b</b>) The peak currents as a function of the square root of the scan rate and the corresponding linear fitting results. (<b>c</b>) Schematic illustration of the mechanisms of the electrochemical tests used to reveal the relationship between ionic conductivity and coating stability. (<b>d</b>) The cyclic voltammetry curves of the conductive fabrics over 12 rounds.</p>
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<p>Antibacterial tests of the fabrics against two commonly used bacterial strains: <span class="html-italic">S. aureus</span> and <span class="html-italic">E. coli</span>. (<b>a</b>) Agar plate tests of different fabrics co-cultured with the two bacteria at 37 °C for 24 h. Inhibition zone diameters of the fabrics decorated with (<b>b</b>) natural polyphenols and (<b>c</b>) natural polyphenol/nanometal composites.</p>
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16 pages, 2636 KiB  
Review
Suspended Particles in Water and Energetically Sustainable Solutions of Their Removal—A Review
by Štěpán Zezulka, Blahoslav Maršálek, Eliška Maršálková, Klára Odehnalová, Marcela Pavlíková and Adéla Lamaczová
Processes 2024, 12(12), 2627; https://doi.org/10.3390/pr12122627 - 22 Nov 2024
Viewed by 95
Abstract
Solid particles (SP) suspended in water represent a common contamination that degrades the water quality, not only in drinking water sources. Particles differ in size, nature, and related features like surface charge. Thus, various methods can be utilized for their removal—physical approaches including [...] Read more.
Solid particles (SP) suspended in water represent a common contamination that degrades the water quality, not only in drinking water sources. Particles differ in size, nature, and related features like surface charge. Thus, various methods can be utilized for their removal—physical approaches including settling or filtration, chemical coagulation/flocculation, biological microbial degradation, and others. This paper aims to summarize currently available methods for SP removal with special attention devoted to alternative, cost-effective, sustainable, and eco-friendly approaches with low energetic demands where the power of renewable energy sources can be utilized. Besides SP properties, the selection of the proper method (or a sequence of methods) for their separation also depends on the purpose of water treatment. Drinking water production demands technologies with immediate effect and high throughputs, like conventional filtration and coagulation/flocculation (electro- or chemical with alternative coagulant/flocculant agents) or some hybrid approaches to ensure quick and cost-effective decontamination. Such technologies usually imply heavy machinery with high electricity consumption, but current progress allows the construction of smaller facilities powered by solar or wind power plant systems. On the other hand, water decontamination in rivers or ponds can include slower processes based on phytoremediation, being long-term sustainable with minimal energy and cost investments. Full article
(This article belongs to the Special Issue Energy and Water Treatment Processes)
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<p>Illustration of the number of scientific works focused on suspended solid particles in water and related topics according to the Core Collection database (September 2024, Web of Science, Clarivate).</p>
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<p>Example of suspended solids from sediment; sand (S) and clay (C) particles on a scanning electron microscopy photograph.</p>
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<p>General scheme of coagulation and flocculation processes using coagulant and flocculant agents to interact with suspended particles and other impurities. In alternative approaches, chemical coagulants and flocculants can be replaced by natural products (starch, ash, etc.) or produced in situ in an electrochemical way from electrode material.</p>
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<p>Illustration of approaches based on phytoremediation, utilizing constructed wetlands, riparian vegetation stripes, and vegetated floating islands. Submersed parts of plants (especially roots or stems) can provide a place for microbial biofilm formation.</p>
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23 pages, 5342 KiB  
Article
Optimization of CO2 Capture Using a New Aqueous Hybrid Solvent (MDEA-[TBPA][TFA]) with a Low Heat Capacity: Integration of COSMO-RS and RSM Approaches
by Fairuz Liyana Mohd Rasdi, Revathi Jeyaseelan, Mohd Faisal Taha and Mohamad Amirul Ashraf Mohd Razip
Processes 2024, 12(12), 2626; https://doi.org/10.3390/pr12122626 - 22 Nov 2024
Viewed by 104
Abstract
This study aims to evaluate the performance of a new hybrid solvent, comprising aqueous MDEA and tetrabutylphosphonium trifluoroacetate ([TBP][TFA]), for CO2 capture and to optimize its CO2 absorption efficiency. First, this study focused on predicting the thermodynamic properties of aqueous MDEAs [...] Read more.
This study aims to evaluate the performance of a new hybrid solvent, comprising aqueous MDEA and tetrabutylphosphonium trifluoroacetate ([TBP][TFA]), for CO2 capture and to optimize its CO2 absorption efficiency. First, this study focused on predicting the thermodynamic properties of aqueous MDEAs and [TBP][TFA] and their interaction energy with CO2 using COSMO-RS. Based on the prediction, it aligns with the principle that CO2 solubility in the MDEA-[TBP][TFA] hybrid solvent decreases as the Henry’s Law constant increases, with the interactions primarily governed by van der Waals forces and hydrogen bonding. The aqueous MDEA-[TBP][TFA] hybrid solvent was prepared in two steps: synthesizing and blending [TBP][TFA] with aqueous MDEAs. The formation and purity of [TBP][TFA] were confirmed through NMR, FT-IR, and Karl Fischer. The heat capacity of the hybrid solvents was lower than their aqueous MDEA solutions. The performance and optimization of CO2 capture were studied using RSM-FC-CCD design, with the optimal value obtained at 50 wt.% MDEA, 20 wt.% [TBP][TFA], 30 °C, and 30 bar (12.14 mol/kg), aligning with COSMO-RS predictions. A 26% reduction in the heat capacity was achieved with the optimal ratio (wt.%) of the hybrid solvent. These findings suggest that the aqueous MDEA-[TBP][TFA] hybrid solvent is a promising alternative for CO2 capture, providing a high removal capacity and lower heat capacity for more efficient regeneration compared to commercial aqueous MDEA solutions. Full article
(This article belongs to the Section Chemical Processes and Systems)
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<p>The schematic diagram of the CO<sub>2</sub> absorption system.</p>
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<p>Solubility of CO<sub>2</sub> in ionic liquid [TBP][TFA], aqueous MDEA (10, 30, and 50 wt.%) at a CO<sub>2</sub> partial pressure range of 2–20 bar at 298.15 K.</p>
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<p>The comparison of Henry’s Law constant value for ionic liquid [TBP][TFA] and aqueous MDEA (10, 30, and 50 wt.%) at 298.15 K.</p>
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<p>Sigma profiles of aqueous MDEA, [TBP][TFA], and CO<sub>2</sub>.</p>
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<p>Sigma potentials of aqueous MDEA, [TBP][TFA], and CO<sub>2</sub>.</p>
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<p>Preparative scheme for [TBP][TFA] ionic liquid.</p>
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<p>(<b>a</b>) <sup>1</sup>H NMR spectrum of [TBP][TFA] and (<b>b</b>) <sup>13</sup>C NMR spectrum of [TBP][TFA] ionic liquid. The letters correspond to their respective peaks, with each peak labeled using the same alphabet.</p>
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<p>FT−IR spectrum of [TBP][TFA] ionic liquid.</p>
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<p>Densities of (<b>a</b>) 10 wt.% aqueous MDEA–[TBP][TFA], (<b>b</b>) 30 wt.% aqueous MDEA–[TBP][TFA], and (<b>c</b>) 50 wt.% aqueous MDEA–[TBP][TFA] containing different [TBP][TFA] concentrations at the temperature range of 20–80 °C.</p>
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<p>Viscosities of (<b>a</b>) 10 wt.% aqueous MDEA–[TBP][TFA], (<b>b</b>) 30 wt.% aqueous MDEA– [TBP][TFA], and (<b>c</b>) 50 wt.% aqueous MDEA–[TBP][TFA] containing different [TBP][TFA] concentrations at the temperature range of 20–80°C.</p>
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<p>Three-dimensional RSM plots illustrating the impact of various parameters on the CO<sub>2</sub> removal capacity: (<b>a</b>) MDEA (wt.%) vs. IL (wt.%); (<b>b</b>) temperature (°C) vs. pressure (bar); (<b>c</b>) MDEA (wt.%) vs. pressure (bar); (<b>d</b>) IL (wt.%) vs. pressure (bar); (<b>e</b>) IL (wt.%) vs. temperature (°C); (<b>f</b>) MDEA (wt.%) vs. temperature (°C). The colors in the 3D RSM plot represent the response values, with colors like blue and green indicating lower values and red indicating higher values. The red and yellow dots in the 3D RSM plot represent specific experimental runs, highlighting critical and intermediate response values.</p>
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<p>Three-dimensional RSM plots illustrating the impact of various parameters on the CO<sub>2</sub> removal capacity: (<b>a</b>) MDEA (wt.%) vs. IL (wt.%); (<b>b</b>) temperature (°C) vs. pressure (bar); (<b>c</b>) MDEA (wt.%) vs. pressure (bar); (<b>d</b>) IL (wt.%) vs. pressure (bar); (<b>e</b>) IL (wt.%) vs. temperature (°C); (<b>f</b>) MDEA (wt.%) vs. temperature (°C). The colors in the 3D RSM plot represent the response values, with colors like blue and green indicating lower values and red indicating higher values. The red and yellow dots in the 3D RSM plot represent specific experimental runs, highlighting critical and intermediate response values.</p>
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<p>Comparison of CO<sub>2</sub> removal capacity and heat capacity at optimum temperatures and pressures.</p>
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16 pages, 4866 KiB  
Article
Emotion Recognition Based on a EEG–fNIRS Hybrid Brain Network in the Source Space
by Mingxing Hou, Xueying Zhang, Guijun Chen, Lixia Huang and Ying Sun
Brain Sci. 2024, 14(12), 1166; https://doi.org/10.3390/brainsci14121166 - 22 Nov 2024
Viewed by 95
Abstract
Background/Objectives: Studies have shown that emotion recognition based on electroencephalogram (EEG) and functional near-infrared spectroscopy (fNIRS) multimodal physiological signals exhibits superior performance compared to that of unimodal approaches. Nonetheless, there remains a paucity of in-depth investigations analyzing the inherent relationship between EEG [...] Read more.
Background/Objectives: Studies have shown that emotion recognition based on electroencephalogram (EEG) and functional near-infrared spectroscopy (fNIRS) multimodal physiological signals exhibits superior performance compared to that of unimodal approaches. Nonetheless, there remains a paucity of in-depth investigations analyzing the inherent relationship between EEG and fNIRS and constructing brain networks to improve the performance of emotion recognition. Methods: In this study, we introduce an innovative method to construct hybrid brain networks in the source space based on simultaneous EEG-fNIRS signals for emotion recognition. Specifically, we perform source localization on EEG signals to derive the EEG source signals. Subsequently, causal brain networks are established in the source space by analyzing the Granger causality between the EEG source signals, while coupled brain networks in the source space are formed by assessing the coupling strength between the EEG source signals and the fNIRS signals. The resultant causal brain networks and coupled brain networks are integrated to create hybrid brain networks in the source space, which serve as features for emotion recognition. Results: The effectiveness of our proposed method is validated on multiple emotion datasets. The experimental results indicate that the recognition performance of our approach significantly surpasses that of the baseline method. Conclusions: This work offers a novel perspective on the fusion of EEG and fNIRS signals in an emotion-evoked experimental paradigm and provides a feasible solution for enhancing emotion recognition performance. Full article
(This article belongs to the Section Neurotechnology and Neuroimaging)
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<p>Experimental setup for EEG–fNIRS data acquisition. (<b>a</b>) Experimental scenario; (<b>b</b>) positions of EEG electrodes and fNIRS optodes.</p>
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<p>Emotion-evoked experimental paradigm.</p>
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<p>The overall flowchart of our approach.</p>
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<p>The schematic diagram of the DKT atlas. (<b>a</b>) Superior view; (<b>b</b>) basal view; (<b>c</b>) lateral view.</p>
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<p>The overall process of calculating a coupling matrix.</p>
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<p>SVM recognition confusion matrices of three brain networks. (<b>a</b>) SG; (<b>b</b>) SC; (<b>c</b>) SG_SC.</p>
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<p>Samples distribution in 2-D feature space. (<b>a</b>) SG; (<b>b</b>) SC; (<b>c</b>) SG_SC.</p>
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<p>Emotion recognition accuracies (%) of SG and EG from three datasets.</p>
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37 pages, 2077 KiB  
Article
Enhancing Cancerous Gene Selection and Classification for High-Dimensional Microarray Data Using a Novel Hybrid Filter and Differential Evolutionary Feature Selection
by Arshad Hashmi, Waleed Ali, Anas Abulfaraj, Faisal Binzagr and Entisar Alkayal
Cancers 2024, 16(23), 3913; https://doi.org/10.3390/cancers16233913 - 22 Nov 2024
Viewed by 140
Abstract
Background: In recent years, microarray datasets have been used to store information about human genes and methods used to express the genes in order to successfully diagnose cancer disease in the early stages. However, most of the microarray datasets typically contain thousands of [...] Read more.
Background: In recent years, microarray datasets have been used to store information about human genes and methods used to express the genes in order to successfully diagnose cancer disease in the early stages. However, most of the microarray datasets typically contain thousands of redundant, irrelevant, and noisy genes, which raises a great challenge for effectively applying the machine learning algorithms to these high-dimensional microarray datasets. Methods: To address this challenge, this paper introduces a proposed hybrid filter and differential evolution-based feature selection to choose only the most influential genes or features of high-dimensional microarray datasets to improve cancer diagnoses and classification. The proposed approach is a two-phase hybrid feature selection model constructed using selecting the top-ranked features by some popular filter feature selection methods and then further identifying the most optimal features conducted by differential evolution (DE) optimization. Accordingly, some popular machine learning algorithms are trained using the final training microarray datasets with only the best features in order to produce outstanding cancer classification results. Four high-dimensional cancerous microarray datasets were used in this study to evaluate the proposed method, which are Breast, Lung, Central Nervous System (CNS), and Brain cancer datasets. Results: The experimental results demonstrate that the classification accuracy results achieved by the proposed hybrid filter-DE over filter methods increased to 100%, 100%, 93%, and 98% on Brain, CNS, Breast and Lung, respectively. Furthermore, applying the suggested DE-based feature selection contributed to removing around 50% of the features selected by using the filter methods for these four cancerous microarray datasets. The average improvement percentages of accuracy achieved by the proposed methods were up to 42.47%, 57.45%, 16.28% and 43.57% compared to the previous works that are 41.43%, 53.66%, 17.53%, 61.70% on Brain, CNS, Lung and Breast datasets, respectively. Conclusions: Compared to the previous works, the proposed methods accomplished better improvement percentages on Brain and CNS datasets, comparable improvement percentages on Lung dataset, and less improvement percentages on Breast dataset. Full article
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<p>The methodology of improving cancer classification in Microarray data using the proposed hybrid filter and differential evolution-based feature selection.</p>
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<p>Comparison of machine learning accuracy on the Brain dataset using all features, filter features, and hybrid filter-DE methods.</p>
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<p>Comparison of machine learning accuracy on the CNS dataset using all features, filter features, and hybrid filter-DE methods.</p>
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<p>Comparison of machine learning accuracy on the Lung dataset using all features, filter features, and hybrid filter-DE features.</p>
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<p>Comparison of accuracy results on the Breast dataset using all features, filter approaches, and the suggested hybrid filter-DE method.</p>
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<p>Comparison of the best accuracy results achieved by filter methods and the proposed hybrid filter-DE feature selection method.</p>
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<p>Comparison of the best results of features selected by filter methods and the proposed hybrid filter-DE feature selection method.</p>
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19 pages, 14784 KiB  
Article
A Data-Driven-Based Grounding Fault Location Method for the Auxiliary Power Supply System in an Electric Locomotive
by Xinyao Hou, Yang Meng and Qiang Ni
Machines 2024, 12(12), 836; https://doi.org/10.3390/machines12120836 - 22 Nov 2024
Viewed by 156
Abstract
Grounding faults are a common type of fault in train auxiliary power supply systems (APS). Timely identification and localization of these faults are crucial for ensuring the stable operation of electric locomotives and the safety of passengers. Therefore, this paper proposes a fault [...] Read more.
Grounding faults are a common type of fault in train auxiliary power supply systems (APS). Timely identification and localization of these faults are crucial for ensuring the stable operation of electric locomotives and the safety of passengers. Therefore, this paper proposes a fault diagnosis method for grounding faults (GFs) that integrates mechanistic insights with data-driven feature extraction. Firstly, this paper analyzes the mechanisms of grounding faults and summarizes the characteristics of their time–frequency distribution. Then, a Short-Time Fourier Transform (STFT) is employed to derive a frequency signature vector enabling classification into three principal categories. Concurrently, a time series sliding window approach is applied to extract time domain indicators for further subdivision of fault types. Finally, a time–frequency hybrid-driven diagnostic model framework is constructed by integrating the frequency distribution with the spatiotemporal map, and validation is conducted using an experimental platform that replicates system fault scenarios with a hardware-in-the-loop (HIL) simulation and executes the real-time diagnostic frameworks on a DSP diagnostic board card. The results demonstrate that the proposed method can detect and accurately locate grounding faults in real time. Full article
(This article belongs to the Section Electrical Machines and Drives)
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<p>The main circuit of a power supply system.</p>
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<p>The principle of the STFT.</p>
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<p>STFT time−frequency analysis of five types of grounding faults. (<b>a</b>) The time−frequency characteristics of fault <span class="html-italic">F</span><sub>1</sub>. (<b>b</b>) The time−frequency characteristics of fault <span class="html-italic">F</span><sub>2</sub>. (<b>c</b>) The time−frequency characteristics of fault <span class="html-italic">F</span><sub>3</sub>. (<b>d</b>) The time−frequency characteristics of fault <span class="html-italic">F</span><sub>4</sub>. (<b>e</b>) The time−frequency characteristics of fault <span class="html-italic">F</span><sub>5</sub>.</p>
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<p>The principle of the time domain feature.</p>
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<p>Schematic diagram of ground fault location and identification.</p>
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<p>The experimental platform.</p>
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<p>Frequency−domain characteristics under different loads: (<b>a</b>) 9 kW load; (<b>b</b>) 100 kW load; (<b>c</b>) 400 kW load.</p>
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<p>The diagnostic accuracy rates of different regional division methods: (<b>a</b>) five types of grounding faults; (<b>b</b>) three categories of fault areas.</p>
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<p>Time−domain characteristics of different grounding faults: (<b>a</b>) time domain characteristics of <span class="html-italic">F</span><sub>1</sub>; (<b>b</b>) time domain characteristics of <span class="html-italic">F</span><sub>2</sub>; (<b>c</b>) time domain characteristics of <span class="html-italic">F</span><sub>4</sub>; and (<b>d</b>) time domain characteristics of <span class="html-italic">F</span><sub>5</sub>.</p>
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<p>The online experimental results of <span class="html-italic">F</span><sub>4</sub>: (<b>a</b>) the original data and grounding anomaly detection; (<b>b</b>) frequency domain characteristics and grounding fault area label; (<b>c</b>) time domain feature variables and grounding fault location label.</p>
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<p>The online experimental results of <span class="html-italic">F</span><sub>4</sub>: (<b>a</b>) the original data and grounding anomaly detection; (<b>b</b>) frequency domain characteristics and grounding fault area label; (<b>c</b>) time domain feature variables and grounding fault location label.</p>
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28 pages, 4540 KiB  
Article
A Novel Hybrid Approach: Integrating Bayesian SPDE and Deep Learning for Enhanced Spatiotemporal Modeling of PM2.5 Concentrations in Urban Airsheds for Sustainable Climate Action and Public Health
by Daniel Patrick Johnson, Niranjan Ravi, Gabriel Filippelli and Asrah Heintzelman
Sustainability 2024, 16(23), 10206; https://doi.org/10.3390/su162310206 - 22 Nov 2024
Viewed by 220
Abstract
This study introduces a novel hybrid model combining Bayesian Stochastic Partial Differential Equations (SPDE) with deep learning, specifically Convolutional Neural Networks (CNN) and Deep Feedforward Neural Networks (DFFNN), to predict PM2.5 concentrations. Traditional models often fail to account for non-linear relationships and [...] Read more.
This study introduces a novel hybrid model combining Bayesian Stochastic Partial Differential Equations (SPDE) with deep learning, specifically Convolutional Neural Networks (CNN) and Deep Feedforward Neural Networks (DFFNN), to predict PM2.5 concentrations. Traditional models often fail to account for non-linear relationships and complex spatial dependencies, critical in urban settings. By integrating SPDE’s spatial-temporal structure with neural networks’ capacity for non-linearity, our model significantly outperforms standalone methods. Accurately predicting air pollution supports sustainable public health strategies and targeted interventions, which are critical for mitigating the adverse health effects of PM2.5, particularly in urban areas heavily impacted by climate change. The hybrid model was applied to the Pleasant Run Airshed in Indianapolis, Indiana, utilizing a comprehensive dataset that included PM2.5 sensor data, meteorological variables, and land-use information. By combining SPDE’s ability to model spatial-temporal structures with the adaptive power of neural networks, the model achieved a high level of predictive accuracy, significantly outperforming standalone methods. Additionally, the model’s interpretability was enhanced through the use of SHAP (Shapley Additive Explanations) values, which provided insights into the contribution of each variable to the model’s predictions. This framework holds the potential for improving air quality monitoring and supports more targeted public health interventions and policy-making efforts. Full article
(This article belongs to the Special Issue Sustainable Climate Action for Global Health)
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<p>Pleasant Run Airshed (PRAS) is located in Indianapolis, Indiana (Marion County, IN, USA), Black points represent PM sensor locations.</p>
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<p>Land cover of the PRAS with PM<sub>2.5</sub> sensor locations highlighted [<a href="#B23-sustainability-16-10206" class="html-bibr">23</a>].</p>
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<p>Wind rose of the PRAS wind data during the study period. Data sourced from the North American Land Data Assimilation System (NLDAS) and the MODIS satellite system [<a href="#B24-sustainability-16-10206" class="html-bibr">24</a>,<a href="#B25-sustainability-16-10206" class="html-bibr">25</a>].</p>
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<p>CNN model diagram showing all layers.</p>
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<p>Highlighted average weekly PM<sub>2.5</sub> levels across all sensors (μg/m<sup>3</sup>) with values at individual sensors subdued. Note: values were missing for most of February due to sensor malfunctions.</p>
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<p>Posterior mean and posterior standard deviation of the spatial random field (μg/m<sup>3</sup>).</p>
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<p>SHAP model output values for each instance (230 from the test set).</p>
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<p>Summary plots of SHAP values for included variables after 999 permutations Base Value = 15.85.</p>
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<p>Variable importance after 999 Permutations (Base Value = 15.85).</p>
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<p>Estimated PM<sub>2.5</sub> concentration using the hybridized Bayesian SPDE—CNN model. Mean RMSE = 2.92 μg/m<sup>3</sup>.</p>
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23 pages, 9394 KiB  
Article
Nonlinear Dynamics and Machine Learning for Robotic Control Systems in IoT Applications
by Vesna Antoska Knights, Olivera Petrovska and Jasenka Gajdoš Kljusurić
Future Internet 2024, 16(12), 435; https://doi.org/10.3390/fi16120435 - 21 Nov 2024
Viewed by 272
Abstract
This paper presents a novel approach to robotic control by integrating nonlinear dynamics with machine learning (ML) in an Internet of Things (IoT) framework. This study addresses the increasing need for adaptable, real-time control systems capable of handling complex, nonlinear dynamic environments and [...] Read more.
This paper presents a novel approach to robotic control by integrating nonlinear dynamics with machine learning (ML) in an Internet of Things (IoT) framework. This study addresses the increasing need for adaptable, real-time control systems capable of handling complex, nonlinear dynamic environments and the importance of machine learning. The proposed hybrid control system is designed for a 20 degrees of freedom (DOFs) robotic platform, combining traditional nonlinear control methods with machine learning models to predict and optimize robotic movements. The machine learning models, including neural networks, are trained using historical data and real-time sensor inputs to dynamically adjust the control parameters. Through simulations, the system demonstrated improved accuracy in trajectory tracking and adaptability, particularly in nonlinear and time-varying environments. The results show that combining traditional control strategies with machine learning significantly enhances the robot’s performance in real-world scenarios. This work offers a foundation for future research into intelligent control systems, with broader implications for industrial applications where precision and adaptability are critical. Full article
(This article belongs to the Special Issue Machine Learning for Blockchain and IoT Systems in Smart City)
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<p>Architecture of the IoT and a robot.</p>
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<p>Architecture of mobile robot and code for generating flier object.</p>
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<p>Command and control process flowchart for robotic operations.</p>
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<p>Hybrid control architecture workflow for robotic systems.</p>
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<p>Neural network-based dynamic control system for robotic actuation.</p>
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<p>Neural network framework for solving nonlinear dynamics optimization in robotic control.</p>
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<p>Block diagram of the control architecture for a mobile robot.</p>
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<p>Hybrid control system integrating neural network and traditional control methods.</p>
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<p>Distribution of orientation, velocity, and acceleration features in training and test datasets.</p>
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<p>Distribution of engineered features reflecting robot dynamics in training and test datasets.</p>
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<p>Correlation matrix of orientation, angular velocity, and linear acceleration parameters.</p>
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<p>Structure of the neural network model.</p>
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<p>Evolution of training metrics over a series of epochs with accuracy and loss.</p>
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<p>Position of the robot’s joints during a cart motion with a trapezoidal velocity profile with a distance of 1 m and a time period of T = 3.5 s.</p>
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<p>Tracking errors during the cart motion with a trapezoidal velocity profile with a distance of 1 m and a time period of T = 3.5 s.</p>
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<p>A detailed visual representation of the simulation: reference ψ<sub>d</sub> and actual ψ course angles and tracking error e<sub>ψ</sub> during the robot’s cart motion with a trapezoidal velocity profile movement.</p>
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<p>Position of the robot’s joints during the circular motion with a radius of 1 m and a time period of T = 3.5 s.</p>
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<p>Tracking errors during the circular motion with a radius of 1 m and a time period of T = 3.5 s.</p>
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<p>A detailed visual representation of the simulation: references and actual trajectories during the robot’s circular motion.</p>
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32 pages, 7951 KiB  
Article
Hybrid Machine Learning for Stunting Prevalence: A Novel Comprehensive Approach to Its Classification, Prediction, and Clustering Optimization in Aceh, Indonesia
by Novia Hasdyna, Rozzi Kesuma Dinata, Rahmi and T. Irfan Fajri
Informatics 2024, 11(4), 89; https://doi.org/10.3390/informatics11040089 - 21 Nov 2024
Viewed by 236
Abstract
Stunting remains a significant public health issue in Aceh, Indonesia, and is influenced by various socio-economic and environmental factors. This study aims to address key challenges in accurately classifying stunting prevalence, predicting future trends, and optimizing clustering methods to support more effective interventions. [...] Read more.
Stunting remains a significant public health issue in Aceh, Indonesia, and is influenced by various socio-economic and environmental factors. This study aims to address key challenges in accurately classifying stunting prevalence, predicting future trends, and optimizing clustering methods to support more effective interventions. To this end, we propose a novel hybrid machine learning framework that integrates classification, predictive modeling, and clustering optimization. Support Vector Machines (SVM) with Radial Basis Function (RBF) and Sigmoid kernels were employed to improve the classification accuracy, with the RBF kernel outperforming the Sigmoid kernel, achieving an accuracy rate of 91.3% compared with 85.6%. This provides a more reliable tool for identifying high-risk populations. Furthermore, linear regression was used for predictive modeling, yielding a low Mean Squared Error (MSE) of 0.137, demonstrating robust predictive accuracy for future stunting prevalence. Finally, the clustering process was optimized using a weighted-product approach to enhance the efficiency of K-Medoids. This optimization reduced the number of iterations from seven to three and improved the Calinski–Harabasz Index from 85.2 to 93.7. This comprehensive framework not only enhances the classification, prediction, and clustering of results but also delivers actionable insights for targeted public health interventions and policymaking aimed at reducing stunting in Aceh. Full article
(This article belongs to the Section Health Informatics)
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<p>The proposed hybrid machine learning framework.</p>
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<p>Framework for Support Vector Machines (SVM).</p>
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<p>The linear regression (LR) framework.</p>
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<p>K-Medoids framework.</p>
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<p>Framework for K-Medoids optimization using the weighted-product method.</p>
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<p>The results of the 10-fold cross-validation process for the RBF kernel in the SVM. (<b>a</b>) Fold-1 results for the RBF kernel in the SVM. (<b>b</b>) Fold-2 results for the RBF kernel in the SVM. (<b>c</b>) Fold-3 results for the RBF kernel in the SVM. (<b>d</b>) Fold-4 results for the RBF kernel in the SVM. (<b>e</b>) Fold-5 results for the RBF kernel in the SVM. (<b>f</b>) Fold-6 results for the RBF kernel in the SVM. (<b>g</b>) Fold-7 results for the RBF kernel in the SVM. (<b>h</b>) Fold-8 results for the RBF kernel in the SVM. (<b>i</b>) Fold-9 results for the RBF kernel in the SVM. (<b>j</b>) Fold-10 results for the RBF kernel in the SVM.</p>
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<p>The results of the 10-fold cross-validation process for the RBF kernel in the SVM. (<b>a</b>) Fold-1 results for the RBF kernel in the SVM. (<b>b</b>) Fold-2 results for the RBF kernel in the SVM. (<b>c</b>) Fold-3 results for the RBF kernel in the SVM. (<b>d</b>) Fold-4 results for the RBF kernel in the SVM. (<b>e</b>) Fold-5 results for the RBF kernel in the SVM. (<b>f</b>) Fold-6 results for the RBF kernel in the SVM. (<b>g</b>) Fold-7 results for the RBF kernel in the SVM. (<b>h</b>) Fold-8 results for the RBF kernel in the SVM. (<b>i</b>) Fold-9 results for the RBF kernel in the SVM. (<b>j</b>) Fold-10 results for the RBF kernel in the SVM.</p>
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<p>Confusion matrices for the RBF kernel.</p>
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<p>Performance of the SVM model using the RBF kernel.</p>
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<p>The results of the 10-fold cross-validation for the Sigmoid kernel in the SVM. (<b>a</b>) Fold-1 results for the Sigmoid kernel in the SVM. (<b>b</b>) Fold-2 results for the Sigmoid kernel in the SVM. (<b>c</b>) Fold-3 results for the Sigmoid kernel in the SVM. (<b>d</b>) Fold-4 results for the Sigmoid Kernel in the SVM. (<b>e</b>) Fold-5 results for the Sigmoid kernel in the SVM. (<b>f</b>) Fold-6 results for the Sigmoid kernel in the SVM. (<b>g</b>) Fold-7 results for the Sigmoid kernel in the SVM. (<b>h</b>) Fold-8 results for the Sigmoid kernel in the SVM. (<b>i</b>) Fold-9 results for the Sigmoid kernel in the SVM. (<b>j</b>) Fold-10 results for the Sigmoid kernel in the SVM.</p>
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<p>The results of the 10-fold cross-validation for the Sigmoid kernel in the SVM. (<b>a</b>) Fold-1 results for the Sigmoid kernel in the SVM. (<b>b</b>) Fold-2 results for the Sigmoid kernel in the SVM. (<b>c</b>) Fold-3 results for the Sigmoid kernel in the SVM. (<b>d</b>) Fold-4 results for the Sigmoid Kernel in the SVM. (<b>e</b>) Fold-5 results for the Sigmoid kernel in the SVM. (<b>f</b>) Fold-6 results for the Sigmoid kernel in the SVM. (<b>g</b>) Fold-7 results for the Sigmoid kernel in the SVM. (<b>h</b>) Fold-8 results for the Sigmoid kernel in the SVM. (<b>i</b>) Fold-9 results for the Sigmoid kernel in the SVM. (<b>j</b>) Fold-10 results for the Sigmoid kernel in the SVM.</p>
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<p>Confusion matrices for the Sigmoid kernel.</p>
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<p>Performance of the SVM model using the Sigmoid kernel.</p>
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<p>The results of the prediction of stunting prevalence in Aceh, Indonesia, using LR.</p>
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<p>The results of the prediction of stunting prevalence in Aceh, Indonesia using LR.</p>
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<p>Comparison of iteration counts between the WP+K-Medoids and conventional K-Medoids methods.</p>
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<p>Comparison of Calinski–Harabasz scores.</p>
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<p>Regions categorized by stunting prevalence in Aceh, Indonesia. (<b>a</b>) The regions categorized under C-0. (<b>b</b>) The regions categorized under C-1. (<b>c</b>) The regions categorized under C-2.</p>
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<p>The clustering results of regions in Aceh based on stunting prevalence.</p>
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Article
Benchmark Dose of Urinary Cadmium for Assessing Renal Tubular and Glomerular Function in a Cadmium-Polluted Area of Japan
by Takuya Hayashi, Kazuhiro Nogawa, Yuuka Watanabe, Teruhiko Kido, Masaru Sakurai, Hideaki Nakagawa and Yasushi Suwazono
Toxics 2024, 12(12), 836; https://doi.org/10.3390/toxics12120836 - 21 Nov 2024
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Abstract
The aim of the present study was to apply an updated benchmark dose (BMD) approach to estimate reference urinary cadmium (U-Cd) for renal tubular and glomerular effects. This cross-sectional survey was conducted 30 years ago in 30 men and 44 women living in [...] Read more.
The aim of the present study was to apply an updated benchmark dose (BMD) approach to estimate reference urinary cadmium (U-Cd) for renal tubular and glomerular effects. This cross-sectional survey was conducted 30 years ago in 30 men and 44 women living in a Cd-polluted area and in 18 men and 18 women living in a non-polluted area. We applied an updated hybrid approach to estimate the BMDs and 95% lower confidence limits (BMDLs) of U-Cd for creatinine (Cr) clearance (CrCl), estimated glomerular filtration rate (eGFR), β2-microglobulin (β2-MG), and β2-MG tubular reabsorption (%TRβ2-MG). Using a benchmark response (BMR) of 5%, we estimated the BMDLs of U-Cd for adverse renal effect markers to be 2.9 (eGFR), 1.8 (β2-MG), 1.8 (%TRβ2-MG < 95%), and 3.6 μg/g Cr (%TRβ2-MG < 90%) in men, and 3.5 (CrCl), 2.5 (β2-MG), 2.6 (%TRβ2-MG < 95%), and 3.9 μg/g Cr (%TRβ2-MG < 90%) in women. The obtained BMDLs for tubular effects were 1.8–3.6 µg/g Cr and for glomerular effects were 2.9–3.5 µg/g Cr; these are not very high compared to the exposure levels in the general population. The BMDLs calculated in this study provide important information for measures regarding protecting general inhabitants or workers from the adverse health effects of Cd exposure. Full article
(This article belongs to the Special Issue Cadmium Pollution and Occupational Exposure)
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<p>Associations between U-Cd and age-adjusted (70 years) markers of renal function, according to the results of multiple regression analyses (significant items only).</p>
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