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Technological Advances in Oral and Maxillofacial Surgery for Diagnosis

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 1802

Special Issue Editor


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Guest Editor
Maxillofacial Surgery Unit, Department of Experimental and Clinical Medicine, Renato Dulbecco Hospital, Magna Graecia University of Catanzaro, Catanzaro, Italy
Interests: head, neck, and oral cavity oncology; oral and maxillo-facial traumatology; salivary gland oncology; oral health in patients with a history of head and neck cancer; role of prognosis factors in head, neck, and oral cavity tumors
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Special Issue Information

Dear Colleagues,

Due to the latest developments in the digitalization of healthcare, the future of medicine is becoming increasingly clear. Developing new technologies has improved the management of pediatric and adult patients, hospital practices, and the targeting of state-of-the-art medical devices. Keeping up with technological progress is necessary to ensure that human beings control technology, not vice versa. The technological revolution in healthcare could transform obsolete practices into more modern techniques and provide cheaper, faster, and more effective solutions against diseases. Numerous new devices are released and promoted worldwide each year, but little is known about their performance and clinical effects. This Special Issue aims to focus on recent advances in medical devices from the following wide range of perspectives:

- Artificial intelligence;

- Health trackers, sensors, and wearables;

- Three-dimensional printers;

- Virtual and augmented reality;

- Nanotechnologies;

- Robotics;

- DNA sequencing.

Through original contributions and review articles, this Special Issue aims to provide evidence of the continuous technological advances made in diagnostic methods for the pathology of maxillofacial surgery, which will offer a unique opportunity in future clinical care.

This Special Issue’s purpose from Diagnostics is to collect the most original articles and review articles on recent technological advances in oral and maxillofacial surgery. In particular, we encourage young specialists (maxillofacial surgeons, ENT, plastic surgeons, neurosurgeons, neuroradiologists) to submit interdisciplinary work and multi-country collaborative research, as well as narrative and systematic reviews and meta-analyses.

Dr. Maria Giulia Cristofaro
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral and maxillofacial surgery
  • oral cancers
  • maxillofacial trauma
  • surgical and informatics technology
  • intraoperative navigation
  • robotic surgery
  • oral and maxillofacial surgery reconstruction
  • nanotechnologies
  • DNA sequencing

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Published Papers (2 papers)

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Research

13 pages, 1341 KiB  
Article
Functional Outcomes and Self-Reported Quality of Life in Patients with Facial Nerve Impairment Following Vestibular Schwannoma Surgery
by Leonardo Franz, Silvia Montino, Anna Agostinelli, Giulia Tealdo, Diego Cazzador, Elisabetta Zanoletti and Gino Marioni
Diagnostics 2024, 14(21), 2387; https://doi.org/10.3390/diagnostics14212387 - 26 Oct 2024
Viewed by 586
Abstract
Objective: The aim of this observational retrospective study was to report quality of life (QoL) in patients with postoperative facial nerve (FN) palsy after vestibular schwannoma (VS) surgery, investigating clinical factors related to functional outcomes. Methods: Forty-eight consecutive patients (M:F 25:23; median age: [...] Read more.
Objective: The aim of this observational retrospective study was to report quality of life (QoL) in patients with postoperative facial nerve (FN) palsy after vestibular schwannoma (VS) surgery, investigating clinical factors related to functional outcomes. Methods: Forty-eight consecutive patients (M:F 25:23; median age: 52.5 years) with facial palsy following surgery for sporadic VS were considered retrospectively. FN palsy was graded by using the Sunnybrook facial grading system (SBFGS), while postoperative QoL and subjective functional aspects were assessed by using the Penn Acoustic Neuroma Quality of Life (PANQOL) Scale, the Synkinesis Assessment Questionnaire, and questions on eating and drinking. Results: A significant correlation emerged between all Sunnybrook scores and median PANQOL domain regarding facial function. Increasing overall SBFGS scores were associated with reduced risk of slow chewing on the affected side (p = 0.004), lack of masticatory strength (p = 0.025), masticatory fatigue (p < 0.001), accumulation of food in the oral vestibule (p < 0.001), difficulty in drinking from a glass (p = 0.019), and fluid spillage while drinking (p = 0.016). Conclusions: This study suggests that the clinical evaluation of patients with FN palsy after VS surgery should be integrated with patient reports about functional outcomes and perceived QoL to help clinicians guide rehabilitation choices. Full article
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<p>(<b>A</b>) Violin plot showing the distribution of overall Sunnybrook scores of patients who underwent facial nerve graft and those who did not; (<b>B</b>) correlation between tumor size and Sunnybrook score (Spearman’s rho: −0.3898; <span class="html-italic">p</span> = 0.0081).</p>
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<p>Correlation between all Sunnybrook scores and the specific PANQOL domain regarding facial function: (<b>A</b>) Sunnybrook total (Spearman’s rho: 0.6150, <span class="html-italic">p</span> &lt; 0.001); (<b>B</b>) symmetry at rest score (Spearman’s rho: −0.5744, <span class="html-italic">p</span> &lt; 0.001); (<b>C</b>) movement symmetry score (Spearman’s rho: 0.6014, <span class="html-italic">p</span> &lt; 0.001); (<b>D</b>) synkinesis score (Spearman’s rho: −0.2899, <span class="html-italic">p</span> = 0. 0457). (<b>E</b>) correlation between overall Sunnybrook score and specific PANQOL domain regarding general health perception (Spearman’s rho: 0.2619, <span class="html-italic">p</span> = 0. 0721).</p>
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14 pages, 4973 KiB  
Article
Classical Orbital Floor Post-Traumatic Reconstruction vs. Customized Reconstruction with the Support of “In-House” 3D-Printed Models: A Retrospective Study with an Analysis of Volumetric Measurement
by Elvis Kallaverja, Ida Barca, Francesco Ferragina and Maria Giulia Cristofaro
Diagnostics 2024, 14(12), 1248; https://doi.org/10.3390/diagnostics14121248 - 13 Jun 2024
Cited by 1 | Viewed by 866
Abstract
Background: Orbital floor fractures (OFFs) represent an interesting chapter in maxillofacial surgery, and one of the main challenges in orbit reconstruction is shaping and cutting the precise contour of the implants due to its complex anatomy. Objective: The aim of the retrospective study [...] Read more.
Background: Orbital floor fractures (OFFs) represent an interesting chapter in maxillofacial surgery, and one of the main challenges in orbit reconstruction is shaping and cutting the precise contour of the implants due to its complex anatomy. Objective: The aim of the retrospective study was to demonstrate, through pre- and postoperative volumetric measurements of the orbit, how the use of a preformed titanium mesh based on the stereolithographic model produced with 3D printers (“In-House” reconstruction) provides a better reconstruction volumetric compared to the intraoperatively shaped titanium mesh. Materials and Methods: The patients with OFF enrolled in this study were divided into two groups according to the inclusion criteria. In Group 1 (G1), patients surgically treated for OFF were divided into two subgroups: G1a, patients undergoing orbital floor reconstruction with an intraoperatively shaped mesh, and G1b, patients undergoing orbital floor reconstruction with a preoperative mesh shaped on a 3D-printed stereolithographic model. Group 2 (G2) consisted of patients treated for other traumatic pathologies (mandible fractures and middle face fractures not involving orbit). Pre- and postoperative orbital volumetric measurements were performed on both G1 and G2. The patients of both groups were subjected to the measurement of orbital volume using Osirix software (Pixmeo SARL, CH-1233 Bernex, Switzerland) on the new CT examination. Both descriptive (using central tendency indices such as mean and range) and regressive (using the Bravais–Pearson index, calculated using the GraphPad program) statistical analyses were performed on the recorded data. Results: From 1 January 2017 to 31 December 2021, of the 176 patients treated for OFF at the “Magna Graecia” University Hospital of Catanzaro 10 fulfilled the study’s inclusion criteria: 5 were assigned to G1a and 5 to G1b, with a total of 30 volumetric measurements. In G2, we included 10 patients, with a total of 20 volumetric measurements. From the volumetric measurements and statistical analysis carried out, it emerged that the average of the volumetric differences of the healthy orbits was ±0.6351 cm3, the standard deviation of the volumetric differences was ±0.3383, and the relationship between the treated orbit and the healthy orbit was linear; therefore, the treated orbital volumes tend to approach the healthy ones after surgical treatment. Conclusion: This study demonstrates that if the volume is restored within the range of the standardized mean, the diplopia is completely recovered already after surgery or after one month. For orbital volumes that do not fall within this range, functional recovery could occur within 6 months or be lacking. The restoration of the orbital volume using pre-modeled networks on the patient’s anatomical model, printed internally in 3D, allows for more accurate reconstructions of the orbital floor in less time, with clinical advantages also in terms of surgical timing. Full article
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<p>Measurement landmarks.</p>
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<p>(<b>A</b>) Preoperative orbital volume measurement including herniated soft tissues. (<b>B</b>) Postoperative orbital volume measurement.</p>
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<p>Volume calculation.</p>
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<p>(<b>A</b>) DICOM file of a 3D reconstruction, using Radiant. (<b>B</b>) Meshmixer solid stereolithographic file. (<b>C</b>) Ultimaker CURA 3D printing file. (<b>D</b>) Titanium mesh shaped on the 3D printed patient anatomical model.</p>
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<p>Comparison of the differences in preoperative and postoperative volumes.</p>
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<p>Comparison of the difference in recovery volumes.</p>
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<p>Graph showing the linear relationship between healthy orbital volumes and treated orbital volumes.</p>
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<p>Comparison of surgical timing between G1a an G1b.</p>
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