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Proceedings
Background: Urinary tract infections (UTIs) are considered common facilitating factors along with other infections in triggering febrile seizures (FS). The main purpose of our study was to identify specific patterns of UTIs, using a combination of inflammatory biomarkers, in order to differentiate UTIs from other bacterial diseases triggering FS. Method: This study included a number of 197 distinct FS events from patients hospitalized in the Pediatric Clinical Hospital Sibiu, among which 10.2% were diagnosed with UTIs. Results: In one-third of the patients with UTI, the symptoms were limited to fever and FS. Using Two-Step cluster analysis, a distinct inflammatory pattern has emerged: higher platelet distribution of the population (PDW), platelet large cell ratio (P-LCR), mean platelet volume (MPV), C-Reactive Protein (CRP), and neutrophil to lymphocyte ratio (NLR). This pattern was associated mainly with bacterial lower respiratory infections. UTIs were highly unlikely in the patie...
Journal of Comprehensive Pediatrics, 2018
Journal of Nephropathology, 2019
Introduction: Febrile convulsion (FC) is the most common seizure disorder in childhood. Few studies focused on epidemiologic characteristics of urinary tract infections accompanied by FC. Objectives: To evaluate prevalence and incidence rates of FC among children with urinary tract infection. Patients and Methods: An observational study in epidemiology was performed in nephrology clinic of a tertiary children hospital from June 2002 to 2016. Totally 1242 cases were followed and those aged 6-60 months enrolled in the study. Demographic characteristics were compared between patients with and without FC. Results: 784 cases including 704 girls (89.8%) and 80 boys (10.2%) enrolled. Twenty-five patients (3.18%) presented with FC. FC occurred in 25 of 503 cases (5%) with febrile urinary tract infection. Twenty girls and 5 boys were in FC and 684 girls and 75 boys were in non-FC groups (P= 0.1). The average age in FC and non-FC groups were 15.52±8.4 and 25.16± 16 months respectively (P=0.00...
International Journal of Contemporary Medical Research [IJCMR], 2019
Open Access Macedonian Journal of Medical Sciences, 2021
BACKGROUND: The occurrence of febrile seizure is affected by numerous factors, but some studies indicated that inflammatory cytokines might contribute to the development of febrile seizure. In resource limited settings, complete blood count (CBC) might serve as potential indices for inflammatory response. AIM: The aim of the present study was to determine the role of mean platelet ratio and neutrophil to lymphocyte ratio (NLR) on the risk of febrile seizures in children aged 6–24 months and 25–59 months at S.K. Lerik Regional Public Hospital in Kupang City, East Nusa Tenggara, Indonesia. METHODS: A case-control study was carried out in 104 patients (52 in the case group and 52 in the control group) aged 6–59 months. The CBC tests were taken on the first visit in the emergency room at S.K. Lerik Regional Public Hospital. RESULTS: Our study found that the odds for experiencing febrile seizure in younger children aged 6–24 months were 3.281 (95% confidence interval 1.470, 7.324) times ...
Medico-Legal Update, 2020
Introduction: Bacterial meningitis (BM) is a serious infection characterized by inflammation of themeninges, causing a high rate of acute complications in children. This research aimed to explain the effect ofprocalcitonin (PCT) in BM and its correlation with the others some inflammatory biomarkers.Method: The case-control study included Fifty children who were diagnosed with suspected bacterialmeningitis associated with febrile seizure according to the clinical investigation by specialized pediatricianand analysis of CSF and Forty children were enrolled as healthy control. The inflammatory biomarkersprocalcitonin, Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) were estimated for eachparticipants in addition to measurement of CBC(complete blood count) by using an automated instrument.Results: Patients have significantly higher serum levels of PRO, CRP, ESR, total WBC count, ANC, andNLR than the control group. Elevating serum PRO and CRP levels in patients group were ...
Annals of Medical Research, 2021
Children
With limited sample sizes and varying study outcomes regarding complete blood count (CBC)-associated biomarkers and their febrile seizure (FS) classification, along with limited research on osmolarity, this study aims to evaluate CBC-associated biomarkers, including osmolarity, for a comprehensive view of their diagnostic value. This single-center retrospective study used data from 364 children (aged 5–60 months) diagnosed with FS. The patients were categorized into simple FS (n = 221) and complex FS (n = 143) groups. CBC and biochemical tests, including sodium, potassium, chloride, glucose, blood urea nitrogen, and C-reactive protein levels, were evaluated. The neutrophil-to-lymphocyte ratio (NLR), mean platelet volume-to-lymphocyte ratio, and osmolarity were calculated and compared between FS types and the number of seizures. Receiver operating characteristic (ROC) curve analysis was conducted to assess the predictive utility of these markers. Inflammatory markers, including NLR, ...
Scholars Journal of Applied Medical Sciences
Background: A febrile seizure is the most common seizure disorder in the pediatric age group. Various extra cranial infections are associated with febrile seizures. For proper management, the underlying infection causing febrile illness has to be sorted out. This associated illness plays an important role in the outcome. Objective: The main objective of this study was to find out infections associated with febrile seizures in children and find out the common type and site of infection were also found. Method and Materials: It was a cross-sectional study. This study was carried out in Dhaka Medical College Hospital, Dhaka for 6 months from 1st January 2018 to 30th June 2018. This study included 60 patients with febrile seizures aged 6 months to 60 months. A detailed history was taken and a thorough clinical examination was done. Appropriate investigations were done to support or exclude other diagnoses and to find out associated infections. Twenty patients were excluded as their clin...
Brain Sciences, 2021
Background: Inflammatory markers association with many diseases is the subject of many articles and reviews. This study presents a comprehensive bibliometric review and visualization analysis of inflammatory biomarkers (IB) in the context of febrile seizure (FS) patients. Methods: The study focused on IB in FS using (1) bibliometric analysis specific indicators and maps in order to analyze and present the network of authors, journals, universities, and countries, and (2) automated literature screening and unsupervised clustering approach for filtering and topic cluster identification. Results: We conducted a literature mining search on FS research, specifically IB in the context of FS, using the automated tools VOSviewer and Bibliometrix. Indices of the inflammatory response (in the context of febrile seizures) identified by the literature mining are (pro/anti-inflammatory) cytokines, such as interleukin IL-1β, IL-6, IL-8, I-10, IL-22, tumor necrosis factor (TNF-α), neutrophil-to-ly...
African Journal of Paediatric Nephrology, 2014
Perspectivas de las ciencias sociales aplicadas: reflexiones sobre la sociedad y el cambio 3 (Atena Editora), 2024
Education Sciences, 2024
Meeting for a Fraternal Dialogue - Caserta on Friday 18 and Saturday 19 October 2024.
ГРАНИЦА ДРЕВНОСТИ И СРЕДНЕВЕКОВЬЯ НА СРЕДНЕМ ЕНИСЕЕ , 2023
Reflexivity analysis for the systematic literature review of the causes and conditions of the constitutional crisis in Poland, 2024
Journal of Animal and Poultry Production
TEMATICS: Technology Management and Informatics Research Journals
Revista Brasileira de Saúde Materno Infantil, 2006
Irish Journal of Psychological Medicine, 2017
The Seventeenth Century, 2019
Geological Society of America Bulletin, 2018
European Journal of Medical Genetics and Clinical Biology, 2024
International Journal of Engineering and Management Kesearch, 2013
Modern Applied Science, 2016