The Kushan Empire (Bactrian: Κυϸανο, Kushano; Sanskrit: कुषाण राजवंश Kuṣāṇ Rājavaṃśa; BHS: Guṣāṇa-vaṃśa; Parthian: 𐭊𐭅𐭔𐭍 𐭇𐭔𐭕𐭓 Kušan-xšaθr) was a syncretic Empire formed by Yuezhi in the Bactrian territories in the early 1st century. It spread to encompass much of Afghanistan, and then the northern parts of the Indian subcontinent at least as far as Saketa and Sarnath near Varanasi (Benares), where inscriptions have been found dating to the era of the Kushan emperor Kanishka the Great. Emperor Kanishka was a great patron of Buddhism; however, as Kushans expanded southward, the deities of its later coinage came to reflect its new Hindu majority.

The Kushans were one of five branches of the Yuezhi confederation, a possibly Iranian or Tocharian,Indo-European nomadic people who migrated from the Tarim Basin (modern Xinjiang) and settled in ancient Bactria. The Kushans possibly used the Greek language initially for administrative purposes, but soon began to use Bactrian language. Kanishka sent his armies north of the Karakoram mountains, capturing territories as far as Kashgar, Khotan and Yarkant, in the Tarim Basin of modern-day Xinjiang, China. A direct road from Gandhara to China remained under Kushan control for more than a century, encouraging travel across the Karakoram and facilitating the spread of Mahayana Buddhism to China.