Aaron Ciechanover ( pronunciation  ah-hah-ROHN chee-HAH-noh-vehr; אהרן צ'חנובר; born October 1, 1947) is an Israeli biologist, who won the Nobel prize in Chemistry for characterizing the method that cells use to degrade and recycle proteins using ubiquitin.

Biography

Ciechanover was born in Haifa, a year before the establishment of Israel. He is the son of Bluma (Lubashevsky), a teacher of English, and Yitzhak Ciechanover, an office worker. His family were Jewish immigrants from Poland before World War II.

He earned a master's degree in science in 1971 and graduated from Hadassah Medical School in Jerusalem in 1974. He received his doctorate in biochemistry in 1981 from the Technion – Israel Institute of Technology in Haifa before conducting postdoctoral research in the laboratory of Harvey Lodish at the Whitehead Institute at MIT from 1981-1984. He is currently a Technion Distinguished Research Professor in the Ruth and Bruce Rappaport Faculty of Medicine and Research Institute at the Technion.

In the Hebrew Bible and the Quran, Aaron אַהֲרֹן (UK /ˈɛərən/, US /ˈærən/) was the older brother of Moses (Exodus 6:16-20, 7:7; Qur'an 28:34) and a prophet of God. Unlike Moses, who grew up in the Egyptian royal court, Aaron and his elder sister Miriam remained with their kinsmen in the eastern border-land of Egypt (Goshen). When Moses first confronted the Egyptian king about the Israelites, Aaron served as his brother's spokesman ("prophet") to Pharaoh. (Exodus 7:1) Part of the Law (Torah) that Moses received from God at Sinai granted Aaron the priesthood for himself and his male descendants, and he became the first High Priest of the Israelites. Various dates for his life have been proposed, ranging from approximately 1600 to 1200 BC. Aaron died before the Israelites crossed the Jordan river and he was buried on Mount Hor (Numbers 33:39; Deuteronomy 10:6 says he died and was buried at Moserah). Aaron is also mentioned in the New Testament of the Bible.

Account in the Hebrew Bible

Aaron Scotus, Irish abbot and musician, fl. late 10th century – 14 December 1052.

Background

Aaron was an Irish abbot and music theorist, the term Scotus at the time denoting Irish (person).

St. Martin's of Cologne

A Benedictine, Scotus was the abbot of St. Martin, Cologne, Germany in the year 1042. He pilgrimaged in his youth to Colonia to the Gaelic-Irish convent of St. Martin. He became abbot of the same in 1042. He was identified with Aaron, abbot of St. Pantaleon. Today historians reject this identification.

Work as a composer

It is believed that he first introduced the Gregorian evening service (nocturns) into Germany. He authored two historically important treaties: De utilitate cantus vocalis et de modo cantandi atque psallendi and De regulis tonorum et symphoniarum. The library of St. Martin, Cologne conserves his work Tractatum de utilitate cantus vocalis et de modo cantandi atque psallendi. He wrote three musical treatises, all of which have been lost.

Aaron died on December 14, 1052.

The characters from the American drama/adventure television series Lost were created by Damon Lindelof and J. J. Abrams. The series follows the lives of plane crash survivors on a mysterious tropical island, after a commercial passenger jet from the fictional Oceanic Airlines crashes somewhere in the South Pacific. Each episode typically features a primary storyline on the island as well as a secondary storyline, a flashback from another point in a character's life.

Out of the 324 people on board Oceanic Flight 815, there are 71 initial survivors (70 humans and one dog) spread across the three sections of the plane crash. The opening season featured 14 regular speaking roles, making it the largest cast in American prime time television when it premiered.

Casting and development