Cox Media Group, Inc., a subsidiary of Atlanta-based Cox Enterprises, is an integrated broadcasting, publishing and digital media company that also includes the direct marketing company Valpak and the national advertising rep firms of Cox Reps. The company operations include 15 broadcast television stations and one local cable channel, 86 radio stations, four metro newspapers, more than a dozen non-daily publications and more than 100 digital services. Cox Media Group is headquartered at 6205 Peachtree Dunwoody Road in Atlanta, Georgia.

In December 2008, Cox Enterprises created Cox Media Group (CMG) by merging Cox Newspapers,Cox Radio and Cox Television into one integrated digital media company. The creation of Cox Media Group was a departure from grouping subsidiaries based solely on publishing medium.

In August 2009, Cox Enterprises realigned its radio, television, newspaper/publishing, and digital assets into the same division. Under the new structure, while the local brands remain independent, they share resources and some management. Dayton, Ohio, was considered the prototype for the media group, where radio, television, newspaper, and direct mail were all in the same market and were combined into a new building. In other markets where the facilities aren't as close together, they do share some senior management; for example Houston & San Antonio Radio and the Austin American-Statesman newspaper all fall under the same regional vice president. In addition to the radio/TV stations and newspapers, Cox Media Group encompasses Cox Digital Solutions (digital sales for both Cox and non-Cox online and mobile properties), Cox Reps (national TV sales for station groups such as Gray and Gannett), Kudzu.com, Savings.com, and Valpak direct mail.

The surname Cox is of English or Welsh origin, and may have originated independently in several places in Great Britain, with the variations arriving at a standard spelling only later. There are also two native Irish surnames which were anglicised into Cox.

An early record of the surname dates from 1556 with the marriage of Alicea Cox at St. Martin in the Fields, Westminster, London. Cox is the 69th-most common surname in the United Kingdom.

Origin

One possibility of the origin is that it is a version of the Old English cocc which means "the little", and was sometimes put after the name of a leader or chieftain as a term of endearment. Surnames such as Wilcox, Willcocks and Willcox are examples of this practice: all are composed of the name William and the archaic word cocc, coming together to mean "little William". The suggestion is that only the element -cox may have endured as a surname for some families.

Another opinion is that the name is derived from the Old English cock, which means a "heap" or "mound", and was a topographic name for a man living near any heap, hill or other bundle. Names like Haycock or Haycox come from such practice, meaning from "the hay mounds" or "the hay fields". Again, the element -cox may have only been carried on in some families.

Cytochrome c oxidase subunit 2, also known as cytochrome c oxidase polypeptide II, is a protein that in humans is encoded by the MT-CO2 gene.

Cytochrome c oxidase subunit II, abbreviated COXII, COX2, COII, or MT-CO2, is the second subunit of cytochrome c oxidase.

Structure

Cytochrome c oxidase (EC 1.9.3.1) is an oligomeric enzymatic complex which is a component of the respiratory chain and is involved in the transfer of electrons from cytochrome c to oxygen. In eukaryotes this enzyme complex is located in the mitochondrial inner membrane; in aerobic prokaryotes it is found in the plasma membrane. The enzyme complex consists of 3-4 subunits (prokaryotes) to up to 13 polypeptides (mammals). In Leigh's disease, there may be an abnormality or deficiency of cytochrome oxidase.

Function

Subunit 2 (COII) transfers the electrons from cytochrome c to the catalytic subunit 1. It contains two adjacent transmembrane regions in its N-terminus and the major part of the protein is exposed to the periplasmic or to the mitochondrial intermembrane space, respectively. COII provides the substrate-binding site and contains a copper centre called Cu(A) (see IPR001505), probably the primary acceptor in cytochrome c oxidase. An exception is the corresponding subunit of the cbb3-type oxidase which lacks the copper A redox-centre. Several bacterial COII have a C-terminal extension that contains a covalently bound haem c.

Cyclooxygenase-1 (COX-1), also known as prostaglandin G/H synthase 1, prostaglandin-endoperoxide synthase 1 or prostaglandin H2 synthase 1, is an enzyme that in humans is encoded by the PTGS1 gene.

History

Cyclooxygenase (COX) is the central enzyme in the biosynthetic pathway to prostaglandins from arachidonic acid. This protein was purified more than 20 years ago and cloned in 1988.

Gene and isozymes

There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described.

Born to Die is the second studio album and major-label debut by American singer and songwriter Lana Del Rey. It was released on January 27, 2012 by Interscope Records, Polydor Records, and Stranger Records. Del Rey collaborated with producers including Patrik Berger, Jeff Bhasker, Chris Braide, Emile Haynie, Justin Parker, Rick Nowels, Robopop, and Al Shux to achieve her desired sound. Their efforts resulted in a primarily baroque pop record, which sees additional influences from alternative hip hop, indie pop and trip hop music.

Contemporary music critics were divided in their opinions of Born to Die; some commended its distinctive production, while its repetitiveness and melodramatic tendencies were a recurring complaint. The record debuted at number two on the U.S. Billboard 200 with first-week sales of 77,000 copies; it was later certified platinum by the Recording Industry Association of America (RIAA) after moving one million units. Born to Die reached the peak position on eleven international record charts, and has sold 8.5 million copies worldwide as of May 2015.

"Radio" is a song co-written and recorded by American country music artist Darius Rucker. It was released on July 22, 2013 as the third single from his album True Believers. Rucker wrote the song with Luke Laird and Ashley Gorley.

Content

The song is a reflection on the narrator's teenage years: specifically, of borrowing his mother's car to take his girlfriend for a ride, and listening to songs on the radio while doing so.

Critical reception

The song generally received favorable reviews. Bobby Peacock of Roughstock gave the song four and a half stars out of five, saying that "it sounds like the kind of fun song you would want to hear on the radio at a memorable moment." Peacock praised Rucker's "all-smiles delivery" and the song's "incredibly catchy melody and tight production." He also compared its theme to "I Watched It All (On My Radio)" by Lionel Cartwright. Tammy Ragusa of Country Weekly gave the song an A grade, calling it "the perfect marriage of an artist’s effervescent personality with an upbeat song, this one about the love of music." Billy Dukes of Taste of Country gave the song two and a half stars out of five, writing that "the uptempo tribute to young love, open roads and, of course, the radio is familiar and easy to fall for, especially when powered by Rucker’s unequaled exuberance." However, Dukes also called the song "a little fluffy" and "not difficult to forget."

X-Dream are Marcus Christopher Maichel (born May 1968) and Jan Müller (born February 1970); they are also known as Rough and Rush. They are some of the cult hit producers of psychedelic trance music and hail from Hamburg, Germany.

The latest X-Dream album, We Interface, includes vocals from American singer Ariel Electron.

First work

Muller was educated as a sound engineer. Maichel was a musician familiar with techno and reggae, and was already making electronic music in 1986. In 1989 the pair first met when Marcus was having problems with his PC and someone sent Jan to help fix it. That same year they teamed up to work on a session together. Their first work concentrated on a sound similar to techno with some hip hop elements which got some material released on Tunnel Records.

Trance

During the early 1990s they were first introduced to the trance scene in Hamburg and decided to switch their music to this genre. From 1993 they began releasing several singles on the Hamburg label Tunnel Records, as X-Dream and under many aliases, such as The Pollinator. Two albums followed on Tunnel Records, Trip To Trancesylvania and We Created Our Own Happiness, which were much closer to the original formula of psychedelic trance, although featuring the unmistakable "trippy" early X-Dream sound.