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The 2022 MLS Expansion Draft was a special draft for the Major League Soccer expansion team St. Louis City SC that was held on November 11, 2022. The list of exposed players was revealed on November 10, 2022. The picks were made on November 11, 2022 at 6:30 PM ET with St. Louis City SC selecting Nicholas Gioacchini, Indiana Vassilev, Jonathan Bell, John Nelson, and Jake LaCava.