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- Yuehchukene is a dimeric indole alkaloid natural product that possesses anti-fertility and estrogenic activities. Yuehchukene is isolated from the roots of Murraya paniculata and other species of the plant genus Murraya. Its natural abundance is in the range of 10-52 ppm. Yuehchukene consists of a tetracyclic unit with a C6 indole substituent. Since its discovery no other natural product of similar structure has been found. Particularly, yuehchukene differs from other natural bis-indole alkaloids because it does not seem to be derived from tryptophan. The steric environments of the two nitrogen atoms are very different. One nitrogen is part of a rigid ring system and is shielded by the C6 indole. The other is part of the freely rotating indole making it readily assessable and therefore more reactive. (en)
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- (6S,6aS,10aR)-6-(1H-Indol-3-yl)-7,7,9-trimethyl-5,6,6a,7,8,10a-hexahydroindeno[2,1-b]indole (en)
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- 7859 (xsd:nonNegativeInteger)
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- Chemical structure of yuehchukene (en)
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- Yuehchukene is a dimeric indole alkaloid natural product that possesses anti-fertility and estrogenic activities. Yuehchukene is isolated from the roots of Murraya paniculata and other species of the plant genus Murraya. Its natural abundance is in the range of 10-52 ppm. Yuehchukene consists of a tetracyclic unit with a C6 indole substituent. Since its discovery no other natural product of similar structure has been found. Particularly, yuehchukene differs from other natural bis-indole alkaloids because it does not seem to be derived from tryptophan. (en)
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