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About: P19 cell

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P19 cells is an embryonic carcinoma cell line derived from an embryo-derived teratocarcinoma in mice. The cell line is pluripotent and can differentiate into cell types of all three germ layers. Also, it is the most characterized embryonic carcinoma (EC) cell line that can be induced into cardiac muscle cells and neuronal cells by different specific treatments. Indeed, exposing aggregated P19 cells to dimethyl sulfoxide (DMSO) induces differentiation into cardiac and skeletal muscle. Also, exposing P19 cells to retinoic acid (RA) can differentiate them into neuronal cells.

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  • P19 cells is an embryonic carcinoma cell line derived from an embryo-derived teratocarcinoma in mice. The cell line is pluripotent and can differentiate into cell types of all three germ layers. Also, it is the most characterized embryonic carcinoma (EC) cell line that can be induced into cardiac muscle cells and neuronal cells by different specific treatments. Indeed, exposing aggregated P19 cells to dimethyl sulfoxide (DMSO) induces differentiation into cardiac and skeletal muscle. Also, exposing P19 cells to retinoic acid (RA) can differentiate them into neuronal cells. (en)
  • P19是一種源自小鼠胚胎生殖細胞瘤的胚胎性癌細胞系，可以分化為三個胚層的細胞類型，並且是最具特徵性的胚胎性癌細胞系，可以通過不同的特異性治療方法，誘導為心肌細胞和神經元細胞，例如將密集的P19細胞暴露於二甲基亞碸（DMSO）時會誘導其分化為心肌和骨骼肌細胞，而將P19細胞暴露於視黃酸（RA）時，則可以將其分化為神經元細胞。 (zh)
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  • P19 cells is an embryonic carcinoma cell line derived from an embryo-derived teratocarcinoma in mice. The cell line is pluripotent and can differentiate into cell types of all three germ layers. Also, it is the most characterized embryonic carcinoma (EC) cell line that can be induced into cardiac muscle cells and neuronal cells by different specific treatments. Indeed, exposing aggregated P19 cells to dimethyl sulfoxide (DMSO) induces differentiation into cardiac and skeletal muscle. Also, exposing P19 cells to retinoic acid (RA) can differentiate them into neuronal cells. (en)
  • P19是一種源自小鼠胚胎生殖細胞瘤的胚胎性癌細胞系，可以分化為三個胚層的細胞類型，並且是最具特徵性的胚胎性癌細胞系，可以通過不同的特異性治療方法，誘導為心肌細胞和神經元細胞，例如將密集的P19細胞暴露於二甲基亞碸（DMSO）時會誘導其分化為心肌和骨骼肌細胞，而將P19細胞暴露於視黃酸（RA）時，則可以將其分化為神經元細胞。 (zh)
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  • P19 cell (en)
  • P19细胞 (zh)
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