John Woodworth Wilce (May 12, 1888 – May 17, 1963) was an American football player and coach, physician, and university professor. He served as the head football coach at Ohio State University from 1913 to 1928, compiling a record of 78–33–9. Wilce is best known for coaching the great Chic Harley and leading Ohio State to their first win over archrival Michigan in 1919. He was inducted into the College Football Hall of Fame as a coach in 1954.