José de Jesús Amezcua Contreras (born c. 1975, along with his brothers Adán and Luis, was a leader of the Colima Cartel, a Mexican methamphetamine and meth-precursor smuggling organization. The Colima cartel has become a branch of the Sinaloa Cartel as are the Milenio Cartel, Guadalajara Cartel, and Sonora Cartels.