dbo:abstract
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- In molecular biology, a carbohydrate-binding module (CBM) is a protein domain found in carbohydrate-active enzymes (for example glycoside hydrolases). The majority of these domains have carbohydrate-binding activity. Some of these domains are found on cellulosomal scaffoldin proteins. CBMs were previously known as cellulose-binding domains. CBMs are classified into numerous families, based on amino acid sequence similarity. There are currently (June 2011) 64 families of CBM in the CAZy database. CBMs of microbial glycoside hydrolases play a central role in the recycling of photosynthetically fixed carbon through their binding to specific plant structural polysaccharides. CBMs can recognise both crystalline and amorphous cellulose forms. CBMs are the most common non-catalytic modules associated with enzymes active in plant cell-wall hydrolysis. Many putative CBMs have been identified by amino acid sequence alignments but only a few representatives have been shown experimentally to have a carbohydrate-binding function. (en)
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dbo:symbol
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- CBM27
- CBM49
- CBM_1
- CBM_10
- CBM_11
- CBM_14
- CBM_15
- CBM_17_28
- CBM_19
- CBM_2
- CBM_20
- CBM_21
- CBM_25
- CBM_3
- CBM_48
- CBM_4_9
- CBM_5_12
- CBM_6
- Chitin_bind_1
- Chitin_bind_3
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dbo:thumbnail
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dbo:wikiPageExternalLink
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dbo:wikiPageID
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dbo:wikiPageLength
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- 40624 (xsd:nonNegativeInteger)
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dbo:wikiPageRevisionID
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dbo:wikiPageWikiLink
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dbp:caption
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- three-dimensional structures of three engineered cellulose-binding domains of cellobiohydrolase i from trichoderma reesei, nmr, 18 structures (en)
- crystal structure analysis of crosslinked-wga3/glcnacbeta1,4glcnac complex (en)
- glucoamylase, granular starch-binding domain complex with cyclodextrin, nmr, minimized average structure (en)
- interactions of a family 18 chitinase with the designed inhibitor hm508, and its degradation product, chitobiono-delta-lactone (en)
- cbm4 structure and function (en)
- structure of cbm25 from bacillus halodurans amylase in complex with maltotetraose (en)
- solution structure of type x cbm (en)
- crystal structure of glycosyltrehalose trehalohydrolase from sulfolobus solfataricus (en)
- xylan-binding module cbm15 (en)
- solution structure of a cellulose binding domain from cellulomonas fimi by nuclear magnetic resonance spectroscopy (en)
- family 11 carbohydrate-binding module of cellulosomal cellulase lic26a-cel5e of clostridium thermocellum (en)
- structural and thermodynamic dissection of specific mannan recognition by a carbohydrate-binding module, tmcbm27 (en)
- cbm6ct from clostridium thermocellum in complex with xylopentaose (en)
- crystal structure of the serratia marcescens chitin-binding protein cbp21 y54a mutant. (en)
- crystal structure of a family iiia cbd from clostridium cellulolyticum (en)
- solution structure of the cbm_21 domain from human protein phosphatase 1, regulatory subunit 3b (en)
- structure of fam17 carbohydrate binding module from clostridium cellulovorans (en)
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dbp:cazy
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- CBM2 (en)
- CBM3 (en)
- CBM1 (en)
- CBM10 (en)
- CBM11 (en)
- CBM12 (en)
- CBM14 (en)
- CBM15 (en)
- CBM18 (en)
- CBM19 (en)
- CBM20 (en)
- CBM21 (en)
- CBM22 (en)
- CBM25 (en)
- CBM28 (en)
- CBM33 (en)
- CBM48 (en)
- CBM6 (en)
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dbp:interpro
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- IPR000254 (en)
- IPR001002 (en)
- IPR001919 (en)
- IPR001956 (en)
- IPR002044 (en)
- IPR002557 (en)
- IPR002883 (en)
- IPR003305 (en)
- IPR003610 (en)
- IPR004193 (en)
- IPR004302 (en)
- IPR005036 (en)
- IPR005084 (en)
- IPR005085 (en)
- IPR005086 (en)
- IPR005087 (en)
- IPR005088 (en)
- IPR005089 (en)
- IPR015295 (en)
- IPR019028 (en)
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dbp:name
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- CBM27 (en)
- CBM49 (en)
- CBM_1 (en)
- CBM_10 (en)
- CBM_11 (en)
- CBM_14 (en)
- CBM_15 (en)
- CBM_17/28 (en)
- CBM_19 (en)
- CBM_2 (en)
- CBM_20 (en)
- CBM_21 (en)
- CBM_25 (en)
- CBM_3 (en)
- CBM_4/9 (en)
- CBM_48 (en)
- CBM_5/12 (en)
- CBM_6 (en)
- Chitin_bind_1 (en)
- Chitin_bind_3 (en)
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dbp:pfam
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- PF00187 (en)
- PF00553 (en)
- PF00686 (en)
- PF00734 (en)
- PF00942 (en)
- PF01607 (en)
- PF02013 (en)
- PF02018 (en)
- PF02839 (en)
- PF02922 (en)
- PF03067 (en)
- PF03370 (en)
- PF03422 (en)
- PF03423 (en)
- PF03424 (en)
- PF03425 (en)
- PF03426 (en)
- PF03427 (en)
- PF09212 (en)
- PF09478 (en)
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dbp:pfamClan
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- CL0202 (en)
- CL0369 (en)
- CL0203 (en)
- CL0155 (en)
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dbp:prosite
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- PDOC00025 (en)
- PDOC00485 (en)
- PDOC00486 (en)
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dbp:scop
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dbp:symbol
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- CBM27 (en)
- CBM49 (en)
- CBM_1 (en)
- CBM_10 (en)
- CBM_11 (en)
- CBM_14 (en)
- CBM_15 (en)
- CBM_17_28 (en)
- CBM_19 (en)
- CBM_2 (en)
- CBM_20 (en)
- CBM_21 (en)
- CBM_25 (en)
- CBM_3 (en)
- CBM_48 (en)
- CBM_4_9 (en)
- CBM_5_12 (en)
- CBM_6 (en)
- Chitin_bind_1 (en)
- Chitin_bind_3 (en)
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dbp:wikiPageUsesTemplate
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dcterms:subject
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rdf:type
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rdfs:comment
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- In molecular biology, a carbohydrate-binding module (CBM) is a protein domain found in carbohydrate-active enzymes (for example glycoside hydrolases). The majority of these domains have carbohydrate-binding activity. Some of these domains are found on cellulosomal scaffoldin proteins. CBMs were previously known as cellulose-binding domains. CBMs are classified into numerous families, based on amino acid sequence similarity. There are currently (June 2011) 64 families of CBM in the CAZy database. (en)
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rdfs:label
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- Carbohydrate-binding module (en)
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