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About: Omarigliptin

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Omarigliptin (MK-3102) is a potent, long-acting oral antidiabetic drug of the DPP-4 inhibitor class used for once-weekly treatment of type 2 diabetes and currently under development by Merck & Co. It inhibits DPP-4 to increase incretin levels (GLP-1 and GIP), which inhibit glucagon release, which in turn increases insulin secretion, decreases gastric emptying and decreases blood glucose levels.

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dbo:abstract
  • Omarigliptin (MK-3102) is a potent, long-acting oral antidiabetic drug of the DPP-4 inhibitor class used for once-weekly treatment of type 2 diabetes and currently under development by Merck & Co. It inhibits DPP-4 to increase incretin levels (GLP-1 and GIP), which inhibit glucagon release, which in turn increases insulin secretion, decreases gastric emptying and decreases blood glucose levels. (en)
  • 奥格列汀，即Omarigliptin (MK-3102) ，是一种强效且长效的口服用抗糖尿病药，是一类DPP-4抑制剂。该药物致力于使得2型糖尿病患者能够将用药频率降低到一周一次。该药物由默克藥廠开发。该药物通过抑制DPP-4来提升水平(GLP-1和)，从而抑制胰高血糖素释放，使得胰岛素分泌增加，减缓胃排空，降低血糖水平。 (zh)
dbo:casNumber
  • 1226781-44-7
dbo:chEMBL
  • 2105762
dbo:fdaUniiCode
  • CVP59Q4JE1
dbo:kegg
  • D10317
dbo:pubchem
  • 46209133
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  • None (en)
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  • 17 (xsd:integer)
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  • 1226781 (xsd:integer)
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  • 20 (xsd:integer)
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dbp:kegg
  • D10317 (en)
dbp:legalStatus
  • Developing (en)
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  • 4 (xsd:integer)
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  • 3 (xsd:integer)
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  • 46209133 (xsd:integer)
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  • Oral (en)
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  • 1 (xsd:integer)
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  • CSn1cc2cCN[C@@H]3C[C@@H]N (en)
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  • 1 (xsd:integer)
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  • MKMPWKUAHLTIBJ-ISTRZQFTSA-N (en)
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  • MK-3102 (en)
dbp:unii
  • CVP59Q4JE1 (en)
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rdfs:comment
  • Omarigliptin (MK-3102) is a potent, long-acting oral antidiabetic drug of the DPP-4 inhibitor class used for once-weekly treatment of type 2 diabetes and currently under development by Merck & Co. It inhibits DPP-4 to increase incretin levels (GLP-1 and GIP), which inhibit glucagon release, which in turn increases insulin secretion, decreases gastric emptying and decreases blood glucose levels. (en)
  • 奥格列汀，即Omarigliptin (MK-3102) ，是一种强效且长效的口服用抗糖尿病药，是一类DPP-4抑制剂。该药物致力于使得2型糖尿病患者能够将用药频率降低到一周一次。该药物由默克藥廠开发。该药物通过抑制DPP-4来提升水平(GLP-1和)，从而抑制胰高血糖素释放，使得胰岛素分泌增加，减缓胃排空，降低血糖水平。 (zh)
rdfs:label
  • Omarigliptin (en)
  • 奥格列汀 (zh)
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