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1.
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The SPES Laser Ion Source: Time Structure and Laser Enhancement Measurements with Sm$^{+}$ beam
/ Khwairakpam, O S (Siena U. ; INFN, Legnaro) ; Mancheva, R (CERN ; KU Leuven, Dept. Phys. Astron.) ; Au, M (CERN) ; Bernerd, C (CERN ; KU Leuven, Dept. Phys. Astron.) ; Centofante, L (INFN, Legnaro) ; Chrysalidis, K (CERN) ; Crepieux, B (CERN) ; Fedosseev, V N (CERN) ; Heinke, R (CERN) ; Marchi, T (INFN, Legnaro) et al.
A two-step resonance photo-ionization scheme has been used to ionize samarium atoms in the SPES tantalum hot-cavity ion source. The effect of the ion load on the ion beam time structure and the laser enhancement of the ion yield has been studied at different ion source temperatures. [...]
2024 - 6 p.
- Published in : J. Phys. : Conf. Ser. 2743 (2024) 012066
Fulltext: PDF;
In : 20th International Conference on Ion Sources (ICIS 2023), Victoria, BC, Canada, 17 - 22 Sep 202, pp.012066
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2.
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Target Development towards First Production of High-Molar- Activity $^{44g}$Sc and $^{47}$Sc by Mass Separation at CERN-MEDICIS
/ Mamis, Edgars (CERN ; Latvia U.) ; Duchemin, Charlotte (CERN) ; Berlin, Valentina (CERN) ; Bernerd, Cyril (CERN) ; Bovigny, Mathieu (CERN) ; Chevallay, Eric (CERN) ; Crepieux, Bernard (CERN) ; Gadelshin, Vadim Maratovich (Mainz U., Inst. Phys.) ; Heinke, Reinhard (CERN) ; Hernandez, Ronaldo Mendez (CERN ; Havana, ISCTN) et al.
The radionuclides 43Sc, 44g/mSc, and 47Sc can be produced cost-effectively in sufficient yield for medical research and applications by irradiating natTi and natV target materials with protons. Maximizing the production yield of the therapeutic 47Sc in the highest cross section energy range of 24–70 MeV results in the co-production of long-lived, high-γ-ray-energy 46Sc and 48Sc contaminants if one does not use enriched target materials. [...]
2024 - 28 p.
- Published in : Pharmaceuticals 17 (2024) 390
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3.
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Scandium thermal release from activated natTi and natV target materials in mixed particle fields: Investigation of parameters relevant for isotope mass separation
/ Mamis, E (CERN ; Latvia U.) ; Kalnina, P (CERN ; Latvia U.) ; Duchemin, C (CERN) ; Lambert, L (CERN) ; Conan, N (CERN) ; Deschamps, M (CERN) ; Dorsival, A (CERN) ; Froeschl, R (CERN) ; Ruiz, F Ogallar (CERN) ; Theis, C (CERN) et al.
Scandium (Sc) has gained significant interest in nuclear medicine due to its 43Sc, 44g/mSc, and 47Sc radioactive isotopes being suitable for cancer diagnostics and therapy, offering a promising avenue for theranostics. Various production methods, including irradiation of enriched or naturally abundant calcium (Ca), titanium (Ti), and vanadium (V) materials with different particle beams, have been investigated to produce 43Sc, 44g/mSc, and 47Sc. [...]
2024 - 10 p.
- Published in : Nucl. Instrum. Methods Phys. Res., B 553 (2024) 165400
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Production of $^{{129} \textrm{m}}$Xe and $^{{131} \textrm{m}}$Xe via neutron activation of $^{128}$Xe and $^{130}$Xe at ILL-RHF and NCBJ-MARIA high-flux reactors
/ Chojnacki, M (CERN ; Geneva U.) ; Kulesz, K (CERN ; Geneva U.) ; Michelon, I (CERN ; INFN, Padua) ; Azaryan, N (CERN ; Mickiewicz U., Poznan) ; Barbero, E (CERN) ; Crepieux, B (CERN) ; Lica, R (CERN ; Bucharest, IFIN-HH) ; Murawski, Ł (NCBJ, Swierk) ; Ziemba, M (NCBJ, Swierk) ; Piersa-Siłkowska, M (CERN) et al.
The long-lived xenon isomers $^{{129} \textrm{m}}$Xe and $^{{131} \textrm{m}}$Xe are of interest for the GAMMA-MRI project, which aims at developing a novel imaging modality based on magnetic resonance of polarized unstable tracers. Here, we present the steps leading to and following the production of these two isomers via neutron irradiation of highly-enriched $^{128}$Xe and $^{130}$Xe gas samples at two high-flux reactors, the High-Flux Reactor (Réacteur à haut flux, RHF) at the Institut Laue-Langevin (ILL) and the MARIA reactor at the National Centre for Nuclear Research (NCBJ). [...]
2024 - 8 p.
- Published in : Appl. Radiat. Isot. 205 (2024) 111174
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The SPES laser ion source: Time structure, laser enhancement and efficiency measurements with gallium at ISOLDE Offline 2
/ Khwairakpam, O S (Siena U. ; Marseille, CPT ; INFN, Legnaro) ; Mancheva, R (CERN ; KU Leuven, Dept. Phys. Astron.) ; Au, M (CERN) ; Bernerd, C (CERN ; KU Leuven, Dept. Phys. Astron.) ; Centofante, L (INFN, Legnaro) ; Chrysalidis, K (CERN) ; Crepieux, B (CERN) ; Fedosseev, V N (CERN) ; Heinke, R (CERN) ; Marchi, T (INFN, Legnaro) et al.
The SPES laser ion source has been tested at ISOLDE Offline 2, CERN. A two-step single resonance photo-ionization scheme has been used to ionize gallium atoms in the SPES tantalum hot-cavity ion source. [...]
2024 - 10 p.
- Published in : Nucl. Instrum. Methods Phys. Res., B 548 (2024) 165249
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Targets and ion sources at CERN-ISOLDE — Facilities and developments
/ Rothe, S (CERN) ; Au, M (CERN ; Mainz U.) ; Ballof, J (CERN ; Mainz U.) ; Barbero, E (CERN) ; Bissell, M (CERN) ; Boucherie, A (CERN) ; Bovigny, M (CERN) ; Chrysalidis, K (CERN) ; Crepieux, B (CERN) ; Cruikshank, J (CERN) et al.
At the CERN-ISOLDE radioactive ion beam facility, thick targets are irradiated using a beam of 1.4-GeV protons. One of ISOLDE’s key features is the large choice of ion source types and target materials available, enabling us to select the ideal combination for optimal intensity and purity of the isotopes requested by ISOLDE users. [...]
2023 - 7 p.
- Published in : Nucl. Instrum. Methods Phys. Res., B 542 (2023) 38-44
In : 19th International Conference on Electromagnetic Isotope Separators and Related Topics (EMIS 2022), Daejeon, Korea, 3 - 7 Oct 2022, pp.38-44
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7.
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8.
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10.17181/CERN-OPEN-2022-015
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9.
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CERN-MEDICIS: A Review Since Commissioning in 2017
/ MEDICIS Collaboration
The CERN-MEDICIS (MEDical Isotopes Collected from ISolde) facility has delivered its first radioactive ion beam at CERN (Switzerland) in December 2017 to support the research and development in nuclear medicine using non-conventional radionuclides. Since then, fourteen institutes, including CERN, have joined the collaboration to drive the scientific program of this unique installation and evaluate the needs of the community to improve the research in imaging, diagnostics, radiation therapy and personalized medicine. [...]
2021 - 11 p.
- Published in : Frontiers in Medicine 8 (2021) 693682
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First laser ions at the CERN-MEDICIS facility
/ MEDICIS Collaboration
The CERN-MEDICIS facility aims to produce emerging medical radionuclides for the theranostics approach in nuclear medicine with mass separation of ion beams. To enhance the radioisotope yield and purity of collected samples, the resonance ionization laser ion source MELISSA was constructed, and provided the first laser ions at the facility in 2019. [...]
2020 - 9 p.
- Published in : Hyperfine Interact. 241 (2020) 55
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