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CERN Document Server Encontrados 13 registros  1 - 10siguiente  ir al registro: La búsqueda tardó 1.87 segundos. 
1.
Relative Biological Effectiveness of Antiprotons the AD-4/ACE Experiment / Holzscheiter, Michael ; Alsner, Jan ; Bassler, Niels ; Knudsen, Helge ; Sellner, Stefan ; Sørensen, Brita Singers /AD-4/ACE
Particle beam cancer therapy was introduced by Robert R. Wilson in 1947 based on the advantageous depth dose profile of a particle beam in human-like targets (water) compared to X-rays or electrons. [...]
2017 - 10 p. - Published in : JPS Conf. Proc. 18 (2017) 011039 External link: Fulltext
In : 12th International Conference on Low Energy Antiproton Physics, Kanazawa, Japan, 6 - 11 Mar 2016, pp.011039
2.
Bubble detector measurements of a mixed radiation field from antiproton annihilation / Bassler, Niels (Aarhus U. ; Aarhus U. Hospital) ; Knudsen, Helge (Aarhus U.) ; Møller, Søren Pape (Aarhus U., ISA) ; Petersen, Jørgen B. (Aarhus U. Hospital) ; Rahbek, Dennis (Aarhus U.) ; Uggerhøj, Ulrik I. (Aarhus U.) /AD-4/ACE collaboration
In the light of recent progress in the study of the biological potential of antiproton tumour treatment it is important to be able to characterize the neutron intensity arising from antiproton annihilation using simple, compact and reliable detectors. The intensity of fast neutrons from antiproton annihilation on polystyrene has been measured with bubble detectors and a multiplicity has been derived as well as an estimated neutron equivalent dose. [...]
2006 - 4 p. - Published in : Nucl. Instrum. Methods Phys. Res., B 251 (2006) 269–273
3.
Antiproton radiotherapy / ACE Collaboration
Antiprotons are interesting as a possible future modality in radiation therapy for the following reasons: When fast antiprotons penetrate matter, protons and antiprotons have near identical stopping powers and exhibit equal radiobiology well before the Bragg-peak. But when the antiprotons come to rest at the Bragg-peak, they annihilate, releasing almost 2 GeV per antiproton–proton annihilation. [...]
2008 - 5 p. - Published in : Radiother. Oncol. 86 (2008) 14-19
4.
The antiproton depth–dose curve measured with alanine detectors / Bassler, Niels (Aarhus U., University hospital ; Deutsches Krebsforsch., Heidelberg) ; Hansen, Johnny W (Vejle Hospital, Denmark) ; Palmans, Hugo (Teddington, Natl. Phys. Lab) ; Holzscheiter, Michael H (UNM, Albuquerque) ; Kovacevic, Sandra (Montenegro U.) /AD-4/ACE Collaboration
n this paper we report on the measurement of the antiproton depth–dose curve, with alanine detectors. The results are compared with simulations using the particle energy spectrum calculated by FLUKA, and using the track structure model of Hansen and Olsen for conversion of calculated dose into response. [...]
2008 - 7 p. - Published in : Nucl. Instrum. Methods Phys. Res., B 266 (2008) 929-936
5.
Antiproton Radiotherapy Peripheral Dose from Secondary Neutrons produced in the Annihilation of Antiprotons in the Target / Fahimian, Benjamin P (UCLA, Los Angeles, radiation oncology) ; DeMarco, John J (UCLA, Los Angeles, radiation oncology) ; Keyes, Roy (New Mexico U.) ; Bassler, Niels (Heidelberg, Inst. Radiology) ; Iwamoto, Keisuke S (UCLA, Los Angeles, radiation oncology) ; Zankl, Maria (Helmholtz Zentrum Munchen, Neuherberg) ; Holzscheiter, Michael H (New Mexico U.)
The AD-4/ACE collaboration studies the biological effects of antiprotons with respect to a possible use of antiprotons in cancer therapy. In vitro experiments performed by the collaboration have shown an enhanced biological effectiveness for antiprotons relative to protons. [...]
2009 - 5 p. - Published in : Hyperfine Interact. 194 (2009) 313–318
6.
Calculated LET spectrum from antiproton beams stopping in water / Bassler, Niels (Aarhus U. Hospital ; Deutsches Krebsforsch., Heidelberg) ; Holzscheiter, Michael (UNM, Albuquerque)
Antiprotons have been proposed as a potential modality for radiotherapy because the annihilation at the end of range leads to roughly a doubling of physical dose in the Bragg peak region. So far it has been anticipated that the radiobiology of antiproton beams is similar to that of protons in the entry region of the beam, but very different in the annihilation region, due to the expected high-LET components resulting from the annihilation. [...]
2009 - 3 p. - Published in : Acta Oncologica 48 (2009) 223-226
7.
Biological effectiveness of antiproton annihilation / Holzscheiter, Michael H. (Pbar Medical, Newport Beach) ; Agazaryan, Nzhde (UCLA, Los Angeles (main)) ; Bassler, Niels (Aarhus U. (main)) ; Beyer, Gerd (Geneva, U. Medical Ctr.) ; De Marco, John J. (UCLA, Los Angeles (main)) ; Doser, Michael (CERN) ; Ichioka, Toshiyasu (Aarhus U. (main)) ; Iwamoto, Keisuke S. (UCLA, Los Angeles (main)) ; Knudsen, Helge V. (Aarhus U. (main)) ; Landua, Rolf (CERN) et al.
We describe an experiment designed to determine whether or not the densely ionizing particles emanating from the annihilation of antiprotons produce an increase in “biological dose” in the vicinity of the narrow Bragg peak for antiprotons compared to protons. This experiment is the first direct measurement of the biological effects of antiproton annihilation. [...]
2004 - Published in : Nucl. Instrum. Methods Phys. Res., B 221 (2004) 210-214
In : 12th International Workshop on Low Energy Positron and Positronium Physics, Sandbjerg, Denmark, 19 - 21 Jul 2003, pp.210-214
8.
Biological Effects of Antiprotons Are Antiprotons a Candidate for Cancer Therapy? / ACE Collaboration
2009 Status Report of AD-4 Experiment
CERN-SPSC-2010-001 ; SPSC-SR-054.
- 2010.
Fulltext
9.
Status Report for Experiment AD-4/ACE Biological Effectiveness of Antiproton Annihilation / ACE Collaboration
Status report for experiment AD-4/ACE showing recent progress in RBE measurements for V79 Chinese Hamster cells irradiated with antiprotons. [...]
CERN-SPSC-2009-002 ; SPSC-SR-039.
- 2009.
Fulltext
10.
Antiproton therapy / ACE Collaboration
Radiotherapy is one of the most important means we have for the treatment of localised tumours. It is therefore essential to optimize the technique, and a lot of effort goes into this endeavour. [...]
2008 - 5 p. - Published in : Nucl. Instrum. Methods Phys. Res., B 266 (2008) 530-534

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