Ketamolol
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| Nazivi | |
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| IUPAC naziv
2-[2-[3-(tert-Butilamino)-2-hidroksipropoksi]fenoksi]-N-metilacetamid
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| Identifikacija | |
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3D model (Jmol)
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| ChemSpider | |
| KEGG[1] | |
| UNII |
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| Svojstva | |
| C16H26N2O4 | |
| Molarna masa | 310,39 g·mol−1 |
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa). | |
| Reference infokutije | |
Ketamolol je beta adrenergički antagonist, specifičnije β1-adrenergični blokator.[4]
Sinteza
[уреди | уреди извор]
Reference
[уреди | уреди извор]- ^ Joanne Wixon; Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast. 17 (1): 48—55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
- ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.
- ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.
- ^ Klausner, MA; Irwin, C; Mullane, JF; Shand, DG; Leese, PT; Arnold, JD; Wollberg, W; Wagner, NB; Wagner, GS (1988). „Effect of cetamolol on epinephrine-induced hypokalemia”. Journal of Clinical Pharmacology. 28 (8): 751—6. PMID 2905711. S2CID 30767741. doi:10.1002/j.1552-4604.1988.tb03210.x.
- ^ GB 1458392, "Optically-active 1-aryloxy-2,3-epoxypropane derviatives", published 1976-12-15, assigned to Imperial Chemical Industries Ltd.
- ^ BE 767781, "Alkanolamines", published 1971-11-29, assigned to Imperial Chemical Industries Ltd.
- ^ D. J. Lecount, C. J. Squire, U.S. Patent 4.059.622 (1977 to ICI).