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C h a p t e r 20 The Heart PowerPoint® Lecture Slides prepared by Jason LaPres Lone Star College - North Harris Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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Introduction to Cardiovascular System
The Pulmonary Circuit Carries blood to and from gas exchange surfaces of lungs The Systemic Circuit Carries blood to and from the body Blood alternates between pulmonary circuit and systemic circuit Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System Heartbeat A single contraction of the heart
The entire heart contracts in series First the atria Then the ventricles Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System A system of specialized cardiac muscle cells
Initiates and distributes electrical impulses that stimulate contraction Automaticity Cardiac muscle tissue contracts automatically Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System Structures of the Conducting System
Sinoatrial (SA) node - wall of right atrium Atrioventricular (AV) node - junction between atria and ventricles Conducting cells - throughout myocardium Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System Conducting Cells Interconnect SA and AV nodes
Distribute stimulus through myocardium In the atrium Internodal pathways In the ventricles AV bundle and the bundle branches Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System Heart Rate
SA node generates 80–100 action potentials per minute Parasympathetic stimulation slows heart rate AV node generates 40–60 action potentials per minute Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System The Sinoatrial (SA) Node
In posterior wall of right atrium Contains pacemaker cells Connected to AV node by internodal pathways Begins atrial activation (Step 1) Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System Figure 20–13 Impulse Conduction through the Heart Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System The Atrioventricular (AV) Node
In floor of right atrium Receives impulse from SA node (Step 2) Delays impulse (Step 3) Atrial contraction begins Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System Figure 20–13 Impulse Conduction through the Heart Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System Figure 20–13 Impulse Conduction through the Heart Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System The AV Bundle In the septum
Carries impulse to left and right bundle branches Which conduct to Purkinje fibers (Step 4) And to the moderator band Which conducts to papillary muscles Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System Figure 20–13 Impulse Conduction through the Heart Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System Purkinje Fibers
Distribute impulse through ventricles (Step 5) Atrial contraction is completed Ventricular contraction begins Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System Figure 20–13 Impulse Conduction through the Heart Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System Abnormal Pacemaker Function
Bradycardia: abnormally slow heart rate Tachycardia: abnormally fast heart rate Ectopic pacemaker Abnormal cells Generate high rate of action potentials Bypass conducting system Disrupt ventricular contractions Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System Electrocardiogram (ECG or EKG)
A recording of electrical events in the heart Obtained by electrodes at specific body locations Abnormal patterns diagnose damage Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System Features of an ECG P wave QRS complex T wave
Atria depolarize QRS complex Ventricles depolarize T wave Ventricles repolarize Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System Time Intervals Between ECG Waves P–R interval
From start of atrial depolarization To start of QRS complex Q–T interval From ventricular depolarization To ventricular repolarization Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System Contractile Cells
Purkinje fibers distribute the stimulus to the contractile cells, which make up most of the muscle cells in the heart Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Cardiac Cycle Cardiac cycle = The period between the start of one heartbeat and the beginning of the next Includes both contraction and relaxation Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Conducting System The Cardiac Cycle
Begins with action potential at SA node Transmitted through conducting system Produces action potentials in cardiac muscle cells (contractile cells) Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Cardiac Cycle Phases of the Cardiac Cycle Within any one chamber
Systole (contraction) Diastole (relaxation) Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Cardiac Cycle Cardiac Cycle and Heart Rate At 75 beats per minute
Cardiac cycle lasts about 800 msecs When heart rate increases All phases of cardiac cycle shorten, particularly diastole Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Cardiac Cycle Eight Steps in the Cardiac Cycle Atrial systole
Atrial contraction begins Right and left AV valves are open Atria eject blood into ventricles Filling ventricles Atrial systole ends AV valves close Ventricles contain maximum blood volume Known as end-diastolic volume (EDV) Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Cardiac Cycle Eight Steps in the Cardiac Cycle Ventricular systole
Isovolumetric ventricular contraction Pressure in ventricles rises AV valves shut Ventricular ejection Semilunar valves open Blood flows into pulmonary and aortic trunks Stroke volume (SV) = 60% of end-diastolic volume Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Cardiac Cycle Eight Steps in the Cardiac Cycle
Ventricular pressure falls Semilunar valves close Ventricles contain end-systolic volume (ESV), about 40% of end-diastolic volume Ventricular diastole Ventricular pressure is higher than atrial pressure All heart valves are closed Ventricles relax (isovolumetric relaxation) Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Cardiac Cycle Eight Steps in the Cardiac Cycle
Atrial pressure is higher than ventricular pressure AV valves open Passive atrial filling Passive ventricular filling Cardiac cycle ends The Heart: Cardiac Cycle Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Cardiac Cycle Blood Pressure In any chamber
Rises during systole Falls during diastole Blood flows from high to low pressure Controlled by timing of contractions Directed by one-way valves Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Cardiac Cycle Heart Sounds S1 S2 S3, S4 Loud sounds
Produced by AV valves S2 Produced by semilunar valves S3, S4 Soft sounds Blood flow into ventricles and atrial contraction Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Cardiac Cycle Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Cardiac Cycle Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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The Cardiac Cycle Heart Murmur
Sounds produced by regurgitation through valves Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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Cardiodynamics The movement and force generated by cardiac contractions End-diastolic volume (EDV) End-systolic volume (ESV) Stroke volume (SV) SV = EDV – ESV Cardiac output (CO) The volume pumped by left ventricle in 1 minute Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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Cardiodynamics Cardiac Output CO = HR X SV
CO = cardiac output (mL/min) HR = heart rate (beats/min) SV = stroke volume (mL/beat) Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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Cardiodynamics Factors Affecting Cardiac Output Cardiac output
Adjusted by changes in heart rate or stroke volume Heart rate Adjusted by autonomic nervous system or hormones Stroke volume Adjusted by changing EDV or ESV Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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Cardiodynamics Atrial Reflex Also called Bainbridge reflex
Adjusts heart rate in response to venous return Stretch receptors in right atrium Trigger increase in heart rate Through increased sympathetic activity Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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Cardiodynamics Hormonal Effects on Heart Rate
Increase heart rate (by sympathetic stimulation of SA node) Epinephrine (E) Norepinephrine (NE) Thyroid hormone Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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Cardiodynamics Factors Affecting the Stroke Volume
The EDV: amount of blood a ventricle contains at the end of diastole Filling time: duration of ventricular diastole Venous return: rate of blood flow during ventricular diastole Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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Cardiodynamics The EDV and Stroke Volume At rest With exercise
EDV is low Myocardium stretches less Stroke volume is low With exercise EDV increases Myocardium stretches more Stroke volume increases Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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Cardiodynamics The Frank–Starling Principle Physical Limits
As EDV increases, stroke volume increases Physical Limits Ventricular expansion is limited by Myocardial connective tissue The cardiac (fibrous) skeleton The pericardial sac Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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Cardiodynamics End-Systolic Volume (ESV)
The amount of blood that remains in the ventricle at the end of ventricular systole is the ESV Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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Cardiodynamics Afterload
Is increased by any factor that restricts arterial blood flow As afterload increases, stroke volume decreases Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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Cardiodynamics Heart Rate Control Factors Autonomic nervous system
Sympathetic and parasympathetic Circulating hormones Venous return and stretch receptors Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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Cardiodynamics Stroke Volume Control Factors EDV ESV Filling time
Rate of venous return ESV Preload Contractility Afterload Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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Cardiodynamics Cardiac Reserve
The difference between resting and maximal cardiac output Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
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Cardiodynamics The Heart and Cardiovascular System
Cardiovascular regulation Ensures adequate circulation to body tissues Cardiovascular centers Control heart and peripheral blood vessels Cardiovascular system responds to Changing activity patterns Circulatory emergencies Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
CHAPTER 12 CARDIOVASCULAR SYSTEM
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Introduction to Cardiac Cycle and Cardiac Output
C h a p t e r 20 The Heart PowerPoint® Lecture Slides prepared by Jason LaPres Lone Star College - North Harris Copyright © 2009 Pearson Education, Inc.,
The Cardiovascular System: Cardiac Function
Chapter 20, part 1 The Heart.
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The Cardiovascular System: The Heart Lab 4. Cardiac Muscle Contraction Heart muscle: –Is stimulated by nerves and is self-excitable (automaticity) –Contracts.
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