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5-Metiluridin trifosfat

5-Metiluridin trifosfat je organsko jedinjenje, koje sadrži 10 atoma ugljenika i ima molekulsku masu od 498,168 Da.

5-Metiluridin trifosfat
Klinički podaci
AHFS/Drugs.com triphosphate.html Monografija
Identifikatori
CAS broj ?
ATC kod ?
ChEMBL[1] CHEMBL607677 DaY
Hemijski podaci
Formula C10H17N2O15P3 
Mol. masa 498,168
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

Osobine

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Osobina Vrednost
Broj akceptora vodonika 15
Broj donora vodonika 7
Broj rotacionih veza 8
Particioni koeficijent[2] (ALogP) -2,6
Rastvorljivost[3] (logS, log(mol/L)) 1,5
Polarna površina[4] (PSA, Å2) 288,3

Reference

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  1. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
  2. Ghose, A.K., Viswanadhan V.N., and Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A 102: 3762-3772. DOI:10.1021/jp980230o. 
  3. Tetko IV, Tanchuk VY, Kasheva TN, Villa AE. (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488-1493. DOI:10.1021/ci000392t. PMID 11749573. 
  4. Ertl P., Rohde B., Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714-3717. DOI:10.1021/jm000942e. PMID 11020286. 

Literatura

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Spoljašnje veze

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