Cell to cell junctions direct endothelial responses both in quiescent and angiogenic vessels.
Endothelial cells express both tight and adherens junctions. Although different in their
specific molecular composition, these junctional complexes present a relatively similar
structural and functional arrangement. Transmembrane adhesive proteins that bind
homophilically identical molecules on adjacent cells represent the core component in both
types of junctions. This intercellular recognition starts a sequence of signaling events. Signal …