The CART gene: structure and regulation

G Dominguez - Peptides, 2006 - Elsevier
CART peptides are important neuropeptides that are involved in a variety of physiologic
processes. The regulation of the CART gene is critical since peptides are regulated and
secreted in response to specific stimuli. CART mRNA must also be controlled in order to
respond to specific stimuli such as psychostimulant drugs and leptin. The regulation of the
CART gene is central to maintaining homeostasis of peptide production. The 5′ upstream
region of the CART gene contains powerful regulatory elements that must be involved in …