[HTML][HTML] Molecular characterization of exosomes and their microRNA cargo in human follicular fluid: bioinformatic analysis reveals that exosomal microRNAs control …
M Santonocito, M Vento, MR Guglielmino, R Battaglia… - Fertility and sterility, 2014 - Elsevier
Objective To characterize well-represented microRNAs in human follicular fluid (FF) and to
ascertain whether they are cargo of FF exosomes and whether they are involved in the
regulation of follicle maturation. Design FF exosomes were characterized by nanosight, flow
cytometry, and exosome-specific surface markers. Expression microRNA profiles from total
and exosomal FF were compared with those from plasma of the same women. Setting
University laboratory and an IVF center. Patient (s) Fifteen healthy women who had …
ascertain whether they are cargo of FF exosomes and whether they are involved in the
regulation of follicle maturation. Design FF exosomes were characterized by nanosight, flow
cytometry, and exosome-specific surface markers. Expression microRNA profiles from total
and exosomal FF were compared with those from plasma of the same women. Setting
University laboratory and an IVF center. Patient (s) Fifteen healthy women who had …