An integrated analysis of vaginal bleeding patterns in clinical trials of Implanon®
B Affandi - Contraception, 1998 - Elsevier
The vaginal bleeding patterns observed during the use of the single-rod progestin-only
implant, Implanon®, compared with those seen during the use of the six-capsule implant,
Norplant®, have been analyzed. The acceptability of these bleeding patterns was also
assessed. An integrated analysis of 13 different trials was done, studying reference periods
(RP) of 90 days. These trials included totals of 1716 Implanon users and 689 Norplant users.
There were statistically significant lower mean values over RP 2–8 (the range over RP 2–8 …
implant, Implanon®, compared with those seen during the use of the six-capsule implant,
Norplant®, have been analyzed. The acceptability of these bleeding patterns was also
assessed. An integrated analysis of 13 different trials was done, studying reference periods
(RP) of 90 days. These trials included totals of 1716 Implanon users and 689 Norplant users.
There were statistically significant lower mean values over RP 2–8 (the range over RP 2–8 …