Persuasive technologies for healthcare have great potential to beneficially impact the well-being of individuals with chronic disease, support self-care, and encourage adherence to correct treatment guidelines by non-physician care providers such as medics and community health workers. However healthcare poses special challenges with respect to design and development of persuasive applications. We describe GuideView, a system now undergoing beta testing, that enables interactive, structured, multi-modal delivery of clinical advice and the authoring of such content. Information and advice is presented simultaneously using voice, pictures, video, and animation. GuideView is multi-platform, executing on desktops, over the web, on Pocket PCs, and on Windows Mobile cell-phones.