We present a new software package called Focus that interfaces cryo-transmission electron
microscopy (cryo-EM) data collection with computer image processing. Focus creates a user-
friendly environment to import and manage data recorded by direct electron detectors and
perform elemental image processing tasks in a high-throughput manner while new data is
being acquired at the microscope. It provides the functionality required to remotely monitor
the progress of data collection and data processing, which is essential now that automation …