The results of speckle interferometric observations at the 4.1 m Southern Astrophysical Research Telescope in 2020, as well as earlier unpublished data, are given, totaling 1735 measurements of 1288 resolved pairs and nonresolutions of 1177 targets. We resolved for the first time 59 new pairs or subsystems in known binaries, mostly among nearby dwarf stars. This work continues our long-term speckle program. Its main goal is to monitor orbital motion of close binaries, including members of high-order hierarchies and Hipparcos pairs in the solar neighborhood. We also report observations of 892 members of young moving groups and associations, where we resolved 103 new pairs.